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Ozempic drug supresses desire to smoke, drink and more?

theatlantic.com

61–70 of 504 posts

Re: Ozempic drug supresses desire to smoke, drink and more?

#61
What happens when you reach your target weight with drugs like this?

After having learned potentionally nothing about nutrition, exercise, and self-control, are you stuck on these meds for life out of fear of binge-eating back to your original weight?

FWIW I'm on a hundred-pound roller coaster ride from 300lbs to 200lbs; currently ~215. I've learned a lot about discipline and sustainable habits along the way.

Re: Ozempic drug supresses desire to smoke, drink and more?

#63
post #5

A drug that promotes weight loss, lessens the desire to smoke, drink, etc...sounds too good to be true? From what I have heard, all of these issues come back as soon as someone comes off the drug. So either a person is committing to a lifetime of being dependent on this drug, or a person is committing to some period of time of ideal living, followed by a possible time of depression after reverting to the status quo.

The first days, weeks and months are often the hardest time when quitting a substance. If this drug helps a smoker not smoke for 3 months, by that time the nicotine addiction has weakened considerably. They've gotten past the hardest part. I see no downside to that. Similarly, if a person loses 30 pounds on this drug, then stops using the drug and reverts to normal habits, it will take a while to regain those 30 poun…

This is what I thought as well, that the habits that drive some of these activities would be dramatically weakened, but it looks like the body is not actually re-aligning to a new homeostatis level, so when a person gets off the drug, the body is trying to get back to the old level. I don't think it all comes back to habits, often your body is working really hard against you to get back a level it feels is right(whether that level is 'healthy' or not).

Re: Ozempic drug supresses desire to smoke, drink and more?

#64

Earlier quoted context omitted.

This is exactly what happened to me. The clinic I went to recommended starting out with 1/10 the normal dose for the first month to make sure I would tolerate it. Then we would move up each month. It worked so well I didn't want to move up so for month 2 I stuck with 1/10th the amount. During that month the effects wore off so I had to take more to get the same impact. I chose to just quit. 2 months after quiting I a…

> I am really concerned this is going to lead to a bigger health crises than the one it purported to solve. A lot of diabetics taking it to regulate blood sugar (particular the feedback loop with insulin and hunger) have said it's changed their life... but for people who are merely overweight I think the benefits may not always be worth the side effects. IMO the correlation between weight and health is not as strong…

I think weight is the wrong thing to target for gauging health, but it is the thing that is in everyone's face and easy to see. Undernourishment is just a big of a problem as over-nourishment. Targeting the four horsemen(t2 diabetes, Alzheimer's, heart disease, cancer) is a better use of time and money, but they are relatively much harder to identify early.

Re: Ozempic drug supresses desire to smoke, drink and more?

#65
post #5

A drug that promotes weight loss, lessens the desire to smoke, drink, etc...sounds too good to be true? From what I have heard, all of these issues come back as soon as someone comes off the drug. So either a person is committing to a lifetime of being dependent on this drug, or a person is committing to some period of time of ideal living, followed by a possible time of depression after reverting to the status quo.

For a lot of people, it's kind of a choice of which substance you are going to be dependent on. It's all expensive and sad, but between Ozempic and cigarettes, alcohol, or overeating, Ozempic has got to be healthier, and quite possibly cheaper in the long run.

Healthier in what sense? There is little knowledge of long term side effects and it isn't even approved for weight loss, it is specifically for people with diabetes.

Re: Ozempic drug supresses desire to smoke, drink and more?

#66
post #30

[flagged]

Unfortunately, suggesting that people eat less and exercise more doesn’t seem to actually work that well. We’ve been trying that for decades and the obesity epidemic just keeps getting worse.

Have we though? I seriously doubt doctors are aggressively pushing eating well and exercising. Has anyone ever received a workout plan from their doctor besides some generic PT exercises? Do they develop nutrition plans tailored to you? Do they track your progress? Do they have any incentive for you to actually get better? Do they require regular blood tests and include all the tests that might actually tell them something?

The answer is a resounding no. None of that. Even if you request a blood test, they will include the absolute bare minimum and fight you when you request something like vitamin D or testosterone. General healthcare in the US is farce. You must be your own doctor, do your own research and fight for the care you need and also tolerate doctors telling you that you don't know what you're talking about. Besides being prescribed antibiotics, no doctor has ever fixed any problem I've ever had. I had to do it myself.

Re: Ozempic drug supresses desire to smoke, drink and more?

#67

Earlier quoted context omitted.

This is exactly what happened to me. The clinic I went to recommended starting out with 1/10 the normal dose for the first month to make sure I would tolerate it. Then we would move up each month. It worked so well I didn't want to move up so for month 2 I stuck with 1/10th the amount. During that month the effects wore off so I had to take more to get the same impact. I chose to just quit. 2 months after quiting I a…

> I am really concerned this is going to lead to a bigger health crises than the one it purported to solve. A lot of diabetics taking it to regulate blood sugar (particular the feedback loop with insulin and hunger) have said it's changed their life... but for people who are merely overweight I think the benefits may not always be worth the side effects. IMO the correlation between weight and health is not as strong…

Obesity is the number one cause of heart disease, which is the number one killer in this country. No, its health effects are not being overstated.

Re: Ozempic drug supresses desire to smoke, drink and more?

#68
post #5

A drug that promotes weight loss, lessens the desire to smoke, drink, etc...sounds too good to be true? From what I have heard, all of these issues come back as soon as someone comes off the drug. So either a person is committing to a lifetime of being dependent on this drug, or a person is committing to some period of time of ideal living, followed by a possible time of depression after reverting to the status quo.

I'm not sure why "it stops working when you stop taking it" is used as an argument against these new peptides. This is the way almost every medication we encounter works. Tylenol might get rid of your headache, but that headache can come back tomorrow. Stop taking birth control and you might get pregnant. Stop taking Claritin and your allergies return. Stop taking insulin, and, as with these new peptides, you lose co…

I am not holding Ozempic to needing to be the cure for anything. My point is that people without diabetes are looking to this drug for weight loss, at which point they create a dangerous dependency, with no hard evidence that their actual health improves. This is opposed to coming up with long term solutions that involve re-evaluating daily decisions that lead to some of these diseases in the first place. If Ozempic is a good treatment for blood sugar control, which could be a good factor to consider in weight fluctuation, maybe reduce the amount of sugar one eats?

Re: Ozempic drug supresses desire to smoke, drink and more?

#69

Earlier quoted context omitted.

Sometimes I see people have written a bug in code and I wonder why they didn't just do the obvious and write it without the bug. Personally, every time I'm about to introduce a bug I just choose to not do it.

I mean if you know ahead of time the thing you're doing is going to produce buggy code then yep your analogy holds.

Yeah, it's weird, right? But people keep putting use-after-free bugs everywhere. Like, do the OpenBSD guys not know that this is a bug (and worse, a security bug)? They keep putting them everywhere. A few years ago they stuck one in OpenSMTPD.

Theo de Raadt would benefit from reading some Hacker News.

Re: Ozempic drug supresses desire to smoke, drink and more?

#70
post #17

Earlier quoted context omitted.

Is a drug or drug-like-food (ie, sugar) dependency really the only option?

Most research indicates "yes", conditioned on the consensus of what comprises the modern lifestyle. I've been trying to understand what changed to create the obesity epidemic. Many things contribute, but it's hard to identify the smoking gun. My understanding is that one major lever seems to be the advent of snacks, refrigeration, and microwaves. Drastically reduced food prep overhead has radically alerted eating pat…

It seems pretty obvious that the massive injection of sugar in the 60s and 70s into diets paved the way for pretty much everything else that followed(snacks, fast food, convenient food, etc). I guess we can all ignore that diabetes is driven by insulin resistance and the body's inability to process glucose, which is conveniently also the predominant thing in our food today, because we would rather look the other way and continue living in a fairy tale...that is until we are disease ridden in our 40s, at which point we can live out the rest of our lives on meds and in the hospital.
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