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I have tinnitus, which is pretty annoying. Very excited to see the possibility of treatment for this.
Some generators on https://mynoise.net/ have strong anecdotal evidence of at least temporary clearing of tinnitus. There's even https://mynoise.net/Albums/view.php?album=TinnitusRelief YMMV.
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I’d love to know what silence is like.
Same. Doesn't bother me at all, it's just background noise, but it's not true silence.
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Same. Doesn't bother me at all, it's just background noise, but it's not true silence.
I used to play in bands and go to a lot of concerts without earplugs (mistakes of youth). I’ve had tinnitus for almost 20 years, and I am so used to it now that it’s a non issue. That said, it drove me crazy in the beginning.
I guess I'm just lucky, or my hearing is just so sensitive that what I consider "loud" is actually fairly quiet. I know that I've had problems actually hearing sounds in band practice without using earplugs - I'd just hear a bunch of noise, and often lose the beat because of the inability to hear other musicians clearly.
Hearing is complicated, this is a repost and it's believed many components need to be fixed in order to hear again. A drug (FX-322) was pulled recently after reaching stage 2 clinical trials and had good evidence of regenerating hair cells via progenitors in mice and cadaver.
Hair cells are not even considered the first thing to be damaged when one notices hearing loss. It's considered neurons connecting the audiotry nerve to and from the hair cell via the spiral ganglion cell are lost (both neuron and eventually the cell after a few months/years).
There is currently no way of reconnecting these or regenerating the SG cell.
I also think funding in this area is extremely low (looking at DoD and UK govs commitment's). Given the funding available I think researchers have done great but more money is needed.
We are a long way from a cure. Hearing is complicated, this is a repost and it's believed many components need to be fixed in order to hear again. A drug (FX-322) was pulled recently after reaching stage 2 clinical trials and had good evidence of regenerating hair cells via progenitors in mice and cadaver. Hair cells are not even considered the first thing to be damaged when one notices hearing loss. It's considered…
The subreddit r/tinnitusresearch has good coverage of the scientific efforts. Which as you mentioned are not that many.
We are a long way from a cure. Hearing is complicated, this is a repost and it's believed many components need to be fixed in order to hear again. A drug (FX-322) was pulled recently after reaching stage 2 clinical trials and had good evidence of regenerating hair cells via progenitors in mice and cadaver. Hair cells are not even considered the first thing to be damaged when one notices hearing loss. It's considered…
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I used to play in bands and go to a lot of concerts without earplugs (mistakes of youth). I’ve had tinnitus for almost 20 years, and I am so used to it now that it’s a non issue. That said, it drove me crazy in the beginning.
I used to play in bands and go to concerts without earplugs too, and one of my favorite pastimes is listening to music on loud volumes. Yet I've never developed tinnitus. I guess I'm just lucky, or my hearing is just so sensitive that what I consider "loud" is actually fairly quiet. I know that I've had problems actually hearing sounds in band practice without using earplugs - I'd just hear a bunch of noise, and ofte…
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My hearing is not particularly bad, and my tinnitus tends to come and go depending on the environment. Still, I would love to resolve it once and for all. It's a pretty common condition too.
tinnitus is not always related to hearing, I got mine after my jaw dislocated, I still got my hearing checked just in case and it was completely OK.
We are a long way from a cure. Hearing is complicated, this is a repost and it's believed many components need to be fixed in order to hear again. A drug (FX-322) was pulled recently after reaching stage 2 clinical trials and had good evidence of regenerating hair cells via progenitors in mice and cadaver. Hair cells are not even considered the first thing to be damaged when one notices hearing loss. It's considered…
> The new cells contained transduction channels that relay sound signals and the ability to form connections with auditory neurons — processes essential to hearing.