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In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)

nature.com

61–70 of 170 posts

Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)

#61

I’m no fan of death, but death (by natural causes - age, sickness , accident) has been how different generations have gotten rid some of the worst despots.

Similarly:

"Science progresses one funeral at a time".

https://en.m.wikipedia.org/wiki/Planck%27s_principle

Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)

#63

Earlier quoted context omitted.

Altered Carbon, and to a lesser extend Upload! touch on this dystopian part - the great leveller is that every billionaire will one day die - imagine if that wasn't the case, and they could keep hoarding wealth and having undue political influence.

Would you really want your parents to die, your loved ones, your family, your children, and yourself, all so you could have the satisfaction that at least rich people, and their loved ones, would suffer and die too?

Many people are fundamentally motivated by fairness, and knowing someone else is getting more than they seem to deserve can violate that. Schadenfreude is a thing.

Myself, I think that longevity treatments are unlikely to remain unaffordable to the poor for very long after they are invented — even in a cynical world where the rich are greedy enough to try and keep it for themselves, old-age healthcare is really expensive, so societies which cause this to be cheap will outperform those that keep it for just the powerful.

Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)

#64

Earlier quoted context omitted.

Anti-aging effects in mice*

We've got to be careful or we're going to end up with super-intelligent immortal mice!

Put flowers on their grave

[1] https://en.wikipedia.org/wiki/Flowers_for_Algernon

Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)

#65

I’m no fan of death, but death (by natural causes - age, sickness , accident) has been how different generations have gotten rid some of the worst despots.

Sounds like a self solving problem.

I reckon people will start caring about their despots if they expect to live a millennium under the despots' boot

Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)

#66

I'll be happy if two things happen: 1. I can have "better years" in the same lifespan. Lots of energy at 90 for instance. 2. I can increase the lifespan of my dog by 50 years :)

90 is still an exceptional lifespan even if you take care of yourself. Human system breaks down randomly after the age of 70, and the complete breakdown depends on luck.

Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)

#67
It was a great validation, that reversing epigenetics is possible in the human body, but using Yamanaka factors to do the same thing has much more investment dollars behind it (billions vs millions), so I believe it will be ready on the market faster.

Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)

#68

Earlier quoted context omitted.

Anti-aging effects in mice*

We've got to be careful or we're going to end up with super-intelligent immortal mice!

Super intelligent?

Meh, don’t you mean Hyper-Intelligent pan-dimensional mega beings who commissioned the Earth?

https://www.bbc.co.uk/programmes/profiles/1MmQjXrkwp98jNdc17...

Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)

#69

Am I the only one who thinks immortality is a nightmare? I don't understand people who want to live forever.

One thing I rarely see mentioned in regards to living forever is that during a life you will accumulate mental scars. My wife has lost a sister, and she's witnessed a murder. Neither she nor I are the same after those experiences. I don't think we will ever be. If we lived forever I think we would all become more and more anxious and excentric as time progressed and our souls inevitably became more "scarred". Maybe i…

I agree.

I am starting to think we might reverse biological aging before we resolve psychosocial crises associated with it.

It wouldn't be the first time humanity has introduced physical tools they weren't ready for.

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