Live data from Hacker News

Long Covid risk falls only slightly after vaccination, study shows

nature.com

61–70 of 170 posts

Re: Long Covid risk falls only slightly after vaccination, study shows

#61
post #7
post #3

Quoted post unavailable.

Quoted post unavailable.

Your risk of heart failure is much greater with infection than with vaccination. It turns out that Covid messes up your immune system and will reinfect you multiple times, so there will be no natural herd immunity. And with each infection , your heart failure chances goes up.

Re: Long Covid risk falls only slightly after vaccination, study shows

#62
It seems like there must be a million confounding factors at thing point. Given that immunity eventually wanes and new variants show up, at what point is a person considered no longer 'vaccinated?' I get that people were excited to not need masks anymore, but I'm hanging on to my n95 in most indoor situations, even in my relatively low-risk region.

Re: Long Covid risk falls only slightly after vaccination, study shows

#63
post #56
post #2

There are no conclusions to draw here. The study doesn't "show" anything -- it indicates a need for further research. I'm disappointed that Nature.com is engaging in this kind of sensational journalism. From their own article: > He praises the study, which was difficult to perform because of the amount and quality of data, but adds that it is limited because it does not break the data down by key factors, such as the…

What medications cause anxiety and depression?

Not exactly a medication but alcohol for one.

But many other drugs can cause these sorts of symptoms too including anti-depressants paradoxically.

Re: Long Covid risk falls only slightly after vaccination, study shows

#64

Earlier quoted context omitted.

That's the impression I get from the media. But if not for the media, I wouldn't know anybody was dying of anything. Nobody in any of my social circles have died in over 3 years. Going off what I've personally observed, I've seen no evidence of either a pandemic or the vaccines being dangerous. To be clear, I don't think it's all made up. Just that it's been blown up, completely out of proportion. All of it.

You either believe the statistics, or you don't - but your anecdata is meaningless. The excess mortality figures tell you need to know.

I don't doubt the statistics. I simply don't think the statistics warrant the level of fear the media tells me I should be experiencing.

Re: Long Covid risk falls only slightly after vaccination, study shows

#65

The problem with a study like this is that they probably aren't doing a good job distinguish true long covid from psychosomatic long covid. And there is a lot of evidence that "long covid" correlates much more highly with pre-existing anxiety levels than disease severity. I think long covid exists I just think there is also a lot of psychosomatic long covid and until we have a good diagnostic criteria to differentiat…

The two most easily diagnosable metrics are a blood test showing reactivated EBV and/or a POTS diagnosis (which involves measurements of how your blood pressure and heart rate change while changing positions). Just because someone doesn't have those doesn't mean they aren't suffering long term effects from COVID.

I've had both consistently for about 2 years now, along with some other neurological symptoms post-covid (no clinical anxiety or depression though). It's made me more of a believer in listening to other people's experiences.

Re: Long Covid risk falls only slightly after vaccination, study shows

#66

I am wondering how much immune "budget" do humans have for vaccines? This topic is left unadressed and is extremely worrying, being an existential risk. Basically, the body has a limited amount of unspecialized naive T cells in its lifetime, mostly located/modulated in the thymus gland, which involute quickly with age. I suppose that 1) vaccines increase the rate of specialisation of naive T cells to mature t cells (…

> I am wondering how much immune "budget" do humans have for vaccines? ... Basically, the body has a limited amount of unspecialized naive T cells in its lifetime I'm not a medical professional, so I suspect that my opinion is just as much gibberish as yours clearly is, but with more self-awareness. Anyway, why would that "budget" be "for vaccines" _only_ ? Vaccines trigger the same mechanism as actual viral attacks,…

> I suspect that my opinion is just as much gibberish as yours clearly is, but with more self-awareness.

OK thank you layman for your ad-hominem, I have extensive expertise in medecine and pharmacology and have extensively studied the thymus, spleen, associated peptides and immune and aging biomarkers, so what seems to you as gibberish is actual valid statements or for a few ones, very reasonable and necessary to be asked speculations. But indeed, an expert is often difficult to distinguish from a bullshitter when the layman lacks discernment, a formation in epistemology nor care to check any of the sourced premises.

> why would that "budget" be "for vaccines" _only_ ?

Well for starters I do not question wether there is a budget limit, there is it is a fact. I even explain in detail that a necessary component in the equation are naive lymphocite T and that aging and environement stressors induce an atrophy (involution/shrinkage) of the thymus and therefore of the total number of differentiated mature lymphocytes T. Also obviously I do not say that this only apply for vaccines, real covid is not much different from the spike protein and in fact induce more damage, however the question has to be asked, regardless.

> consider what answer would have better evolutionary fitness

and yet having a limit is an evolutionary fitness as show the existence of thymus involution, both for reduced energy use and programmed aging evolutionnary benefits as shows the many papers on the topic. Obviously, as you should have guessed, the limit only matter to not be reached before the age of reproduction, which is < 20 years old

Re: Long Covid risk falls only slightly after vaccination, study shows

#67

Earlier quoted context omitted.

That's the impression I get from the media. But if not for the media, I wouldn't know anybody was dying of anything. Nobody in any of my social circles have died in over 3 years. Going off what I've personally observed, I've seen no evidence of either a pandemic or the vaccines being dangerous. To be clear, I don't think it's all made up. Just that it's been blown up, completely out of proportion. All of it.

You either believe the statistics, or you don't - but your anecdata is meaningless. The excess mortality figures tell you need to know.

No, they tell you there’s excess mortality. They don’t tell you if it is a result of Covid, of skipping medical care, of lockdowns, of substance abuse, etc.

Some countries experienced essentially no excess death even without vaccines, and some experienced non-Covid attributed excess death independent of vaccines. You really can’t read anything off excess death, except that it exists (where it exists)

Re: Long Covid risk falls only slightly after vaccination, study shows

#68

Is there any evidence that "long covid" is actually a thing?

It sure seems like a lot of people in the medical community are taking it pretty seriously. Given the quantity of medical journal articles discussing long covid, I'm going to go with YES

Re: Long Covid risk falls only slightly after vaccination, study shows

#69

Is there any evidence that "long covid" is actually a thing?

People definitely report it and genuinely believe they have it.. but similar problems occur in a small subset of all people who recover from infectious diseases.

So it may not be covid specific but it does seem to exist and with a wide ranging illness such as covid then obviously more overall people have it than from say pneumonia.

Re: Long Covid risk falls only slightly after vaccination, study shows

#70

Earlier quoted context omitted.

I would love to compare these rates against other common respiratory viruses. Long term effects from viral infections is not unique to covid. The only thing unique about covid is we are watching it 1000x more than anything previous to it. ... if you look for something, you'll find it. Test everybody with a pulse for the flu and then track the long term effects the same way we are with covid and I'm sure you'll see a…

COVID virus spike protein attaches directly to ACE2 receptors which are found all over the blood vessels in the body. It is uniquely evolved to target and damage the vascular system in the body. edit: And people ARE tracking things like flu vs. COVID statistics. So far COVID-19 is roughly 10x as deadly as a bad flu year. Ten times...

> It is uniquely evolved to target and damage the vascular system in the body.

There is so much panic, hysteria and just mythos around covid that I have a hard time believing this. Calling this thing "novel" gave some of these experts a hell of a lot of artistic liberty in how they describe covid.

> And people ARE tracking things like flu vs. COVID statistics. So far COVID-19 is roughly 10x as deadly as a bad flu year. Ten times...

I'm still not fully convinced that due to the massive amount of surveillance we've built around covid, it is even fair to compare the IFR of the flu vs. covid. We've never measured the progress of any virus to this degree. If we tracked the flu the same way we tracked covid, what kinds of numbers would we be getting for that virus?

We have a massive river of data coming in for covid. Vastly more data about it than any other virus in human history. I don't think anybody knows how to process all of it in a way that lets us meaningfully compare it to anything prior.

Post reply on HN