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‘Dancing molecules’ successfully repair severe spinal cord injuries

news.northwestern.edu

61–70 of 104 posts

Re: ‘Dancing molecules’ successfully repair severe spinal cord injuries

#61
post #31

Do I want to know how they get mice with severe spinal cord injuries to test on? I'm guessing it's exactly what I think it is, but I'm wondering if there's another way that it happens.

My brother was researching brain regeneration in rats, and he said they used cryogenically induced lesions as a test bed. So probably something similar.

Re: ‘Dancing molecules’ successfully repair severe spinal cord injuries

#62
post #56

Earlier quoted context omitted.

It’s a sanity check. Can we afford to not do X? because thank God there is some commonality in disgust. Clearly not at the moment, but I doubt even the original authors of those comments care more than you do. It’s a feature and not a bug.

The people insisting on this just want to use HN as their megaphone. There is no debate. They have already made up their minds. It comes off about as well as an insufferable teenager at Thanksgiving dinner. Some feature.

I mean, that's 99% of internet comments. There are many topics I disagree with the HN majority (or vocal minority) on, and it becomes tiresome to see the same old stuff rehashed in every article when it's mostly off topic. But if we didn't allow people to comment unless they were genuinely open to having their mind changed about something, there would be no comments.

If you debate someone on the internet, you will never change their mind. But you might influence the opinion of someone else who reads your comments, and that's the best you can hope for.

Also, when a large number of people are wrong about something, there is often an opportunity of some kind associated with that. An investing opportunity, a career opportunity, a startup opportunity. When you see what others don't it can be a big advantage. So, embrace it.

Re: ‘Dancing molecules’ successfully repair severe spinal cord injuries

#63

Recently every thread on HN about life and death has been devolving into a debate with people who insist that these things need to be addressed in the comments and those that simply don't care. It's honestly exhausting. It's sort of like making food and having someone at the table try to discuss the morality of the meat you're using.... Except it's every. single. time. Lab mice are killed off everyday after experimen…

[deleted]

Re: ‘Dancing molecules’ successfully repair severe spinal cord injuries

#64
post #56

Earlier quoted context omitted.

It’s a sanity check. Can we afford to not do X? because thank God there is some commonality in disgust. Clearly not at the moment, but I doubt even the original authors of those comments care more than you do. It’s a feature and not a bug.

The people insisting on this just want to use HN as their megaphone. There is no debate. They have already made up their minds. It comes off about as well as an insufferable teenager at Thanksgiving dinner. Some feature.

You said in your first comment it "devolves into a debate." Now you're saying there is no debate. Poor consistency/word choice also lowers the value of HN discussion.

Re: ‘Dancing molecules’ successfully repair severe spinal cord injuries

#65

Recently every thread on HN about life and death has been devolving into a debate with people who insist that these things need to be addressed in the comments and those that simply don't care. It's honestly exhausting. It's sort of like making food and having someone at the table try to discuss the morality of the meat you're using.... Except it's every. single. time. Lab mice are killed off everyday after experimen…

Who cares if it’s every single time? It’s not exactly a feat of mental endurance to handle it.

I have a mental debate about animal-based testing/clothes/food on a regular basis, as I do about many choices I make that have a potential moral cost. I still often make those choices, and I don’t lose sleep over it. However, I believe regularly questioning one’s own viewpoints, habits and situation is a strength.

The assumption that it’s being done simply to draw attention is an unreasonable and condescending dismissal.

Re: ‘Dancing molecules’ successfully repair severe spinal cord injuries

#66

Earlier quoted context omitted.

The the answer in the science and medical communities is Almost Never "they're just mice, who cares" It is rather that this is an important experiment that can't be done any other way and can have large benefit for humans

"it can't be done any other way" strikes me as pretty thin. Whereas we may not be able to conceive of another way at this point in time, it does no good to imagine that this condition will continue in perpetuity.

Like the bleeding of horseshoe crabs for LAL it's always reevaluated based on current technology.

Re: ‘Dancing molecules’ successfully repair severe spinal cord injuries

#67

Earlier quoted context omitted.

Maybe a dumb question but.... If scar tissue forms after an injury and blocks the area (on both sides of the nerve, I assume), like this ---x x--- . Could you then cut the scarred area away, creating "new" injury that this treatment could cure? ----x x---- ---| |--- ---**---

I remember reading a story many years ago a about a boy that got a nerve severed and later they opened the wound to remove the scar in the nerve and reconnect the nerve, so it regrows. The problem was that after cutting the scar, the nerve was shorter, so they have to take a shortcut in the elbow. I can't find the story, but these links have info that is similar enough to be confident my memory is not too bad. http:/…

Cool! I am glad that it might be possible and that this might even be able to help those who have old injuries then!

My wife has internal scarring and adhesion(filaments of scar tissues) from appendicitis. This causes complications and her intestines can get twisted instead of moving freely over each other like they normally would. I asked if the adhesion could be cut to allow free movement but unfortunately it's sort of like a hydra, you cut one and it will form more/new adhesions.

Re: ‘Dancing molecules’ successfully repair severe spinal cord injuries

#68

Earlier quoted context omitted.

The the answer in the science and medical communities is Almost Never "they're just mice, who cares" It is rather that this is an important experiment that can't be done any other way and can have large benefit for humans

"it can't be done any other way" strikes me as pretty thin. Whereas we may not be able to conceive of another way at this point in time, it does no good to imagine that this condition will continue in perpetuity.

If you feel that the statement needs to be future proofed, feel free to add "at this time" when you read it.

I think the point still stands with this condition and will for the foreseeable future.

Re: ‘Dancing molecules’ successfully repair severe spinal cord injuries

#69

Recently every thread on HN about life and death has been devolving into a debate with people who insist that these things need to be addressed in the comments and those that simply don't care. It's honestly exhausting. It's sort of like making food and having someone at the table try to discuss the morality of the meat you're using.... Except it's every. single. time. Lab mice are killed off everyday after experimen…

Who cares if it’s every single time? It’s not exactly a feat of mental endurance to handle it. I have a mental debate about animal-based testing/clothes/food on a regular basis, as I do about many choices I make that have a potential moral cost. I still often make those choices, and I don’t lose sleep over it. However, I believe regularly questioning one’s own viewpoints, habits and situation is a strength. The assum…

So we shouldn't care that a site for techies has turned into a megaphone for people with obsessive compulsive disorders encouraged by a mob mentality? It's a medical science thread. Why does someone with nerve damage have to justify themselves to you in every single thread about this? Do you go into food related threads and argue with people in there too? These arguments are tone deaf and like I said earlier; exhausting.

They have no place here. Go to /r/philosophy or something.

Re: ‘Dancing molecules’ successfully repair severe spinal cord injuries

#70

Earlier quoted context omitted.

The people insisting on this just want to use HN as their megaphone. There is no debate. They have already made up their minds. It comes off about as well as an insufferable teenager at Thanksgiving dinner. Some feature.

You said in your first comment it "devolves into a debate." Now you're saying there is no debate. Poor consistency/word choice also lowers the value of HN discussion.

Person A: this is not a good venue to have a debate.

Person B: yes it is

debate ensues

Person B: I thought you were against debates.

Picard facepalm

You know I dated someone with bipolar disorder once. It went exactly like this. It's funny that HN threads exhibit the same behaviors.

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