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The Nobel Prize in Chemistry 2020

nobelprize.org

61–70 of 99 posts

Re: The Nobel Prize in Chemistry 2020

#61
post #20

The discovery is beyond doubt deserving of the award. It was also awarded only 8 years after the publication. It's a bit sad though that Virginijus Šikšnys didn't get any credit for the discovery, because his paper sent over a month earlier was rejected by Cell. https://en.wikipedia.org/wiki/Virginijus_%C5%A0ik%C5%A1nys#P... Edit: The Nobel award paper writes this on his findings: https://www.nobelprize.org/uploads/2…

[deleted]

Re: The Nobel Prize in Chemistry 2020

#63
post #20

The discovery is beyond doubt deserving of the award. It was also awarded only 8 years after the publication. It's a bit sad though that Virginijus Šikšnys didn't get any credit for the discovery, because his paper sent over a month earlier was rejected by Cell. https://en.wikipedia.org/wiki/Virginijus_%C5%A0ik%C5%A1nys#P... Edit: The Nobel award paper writes this on his findings: https://www.nobelprize.org/uploads/2…

This is a complex issue. The good news: Dr. S. has certainly received plenty of recognition (e.g., https://www.nature.com/articles/d41586-018-05308-5 ). Would love to hear an interview with him and his thoughts on who should be recognized.

Yeah, the good news is that everyone involved in the CRISPR discoveries has done extremely well both financially and scientifically, even if they're not getting a trip to Stockholm. It definitely shows the limits of the three-person-max approach, however.

Re: The Nobel Prize in Chemistry 2020

#64
post #7

There was a really interesting debate here on who should get credit for the patent (Charpentier & Doudna vs. Feng Zhang and to a lesser extent George Church, i.e. discovery + characterization vs. making things practical). I find it interesting, but not surprising, to see that only the former are getting the Nobel Prize.

It's a reasonably segmented group. Charpentier and Doudna deserve the breakthrough credit they're getting. Individually Feng Zhang did more to push CRISPR forward than anyone else has thus far. And George Church has had his hands all over the space for a very long time, while not fitting into either of the prior two groups.

It's so big it more than requires all of them, contributing in the ways they have (along with countless others, less heralded, at places like Berkeley or Broad).

Re: The Nobel Prize in Chemistry 2020

#65
post #20

The discovery is beyond doubt deserving of the award. It was also awarded only 8 years after the publication. It's a bit sad though that Virginijus Šikšnys didn't get any credit for the discovery, because his paper sent over a month earlier was rejected by Cell. https://en.wikipedia.org/wiki/Virginijus_%C5%A0ik%C5%A1nys#P... Edit: The Nobel award paper writes this on his findings: https://www.nobelprize.org/uploads/2…

> paper sent over a month earlier was rejected by Cell

Cell rejected an almost-nobel-worthy paper? Is this business as usual? Would they maybe have got the nobel price, if they had submitted to a lesser journal instead of Cell?

Can we make a rule of thumb, that in general you should submit your groundbreaking work to the most prestigious journal possible, but if you feel your work is of nobel caliber, then play it safe and submit to a mediocre journal to avoid the high publication threshold of the top level journals?

Re: The Nobel Prize in Chemistry 2020

#67
post #30

Earlier quoted context omitted.

Sorry, I'm out of the loop on this. Can you explain it a bit more? I was aware of the lawsuit between Berkeley and MIT over the patent, but not of the specifics.

For instance, see http://www.michaeleisen.org/blog/?p=1825

Not that Michael is biased at all, either...

Anyway, I'm happy Jennifer and Emmanuelle won over others and thinks this was the right call. The discovery of the idea was the most important part here, bs showing it in human cells (which wasn't that hard afterwards).

Re: The Nobel Prize in Chemistry 2020

#68
post #27
post #20

The discovery is beyond doubt deserving of the award. It was also awarded only 8 years after the publication. It's a bit sad though that Virginijus Šikšnys didn't get any credit for the discovery, because his paper sent over a month earlier was rejected by Cell. https://en.wikipedia.org/wiki/Virginijus_%C5%A0ik%C5%A1nys#P... Edit: The Nobel award paper writes this on his findings: https://www.nobelprize.org/uploads/2…

Why is academia (at least in the physical sciences) so competitive? My partner is a molecular biologist and she can't collaborate with anyone outside of her lab because of the fear that they collaborators will take their research before they get a chance to publish it. It seems this method of performing groundbreaking research and science is horrifically detrimental to our collective progress. There's no reason for t…

"The Double Helix" by Watson delves into the highly competitive nature of this level of research. It is a candid and entertaining portrayal.

Re: The Nobel Prize in Chemistry 2020

#69

There's a documentary on Netflix "Human Nature" that discusses the history of CRISPR and features interviews with both Emmanuelle Charpentier and Jennifer Doudna. [0][1][2] [0] https://www.netflix.com/title/81220944 [1] https://www.youtube.com/watch?v=_1UkCfDnn6c [2] https://en.wikipedia.org/wiki/Human_Nature_(2019_film)

It was also broadcast through PBS NOVA here in the US (and it is available on PBS Passport -- that is how I watched it). In fact, I thought it was a PBS NOVA episode, but it is apparently an independent film.

Re: The Nobel Prize in Chemistry 2020

#70
post #27
post #20

The discovery is beyond doubt deserving of the award. It was also awarded only 8 years after the publication. It's a bit sad though that Virginijus Šikšnys didn't get any credit for the discovery, because his paper sent over a month earlier was rejected by Cell. https://en.wikipedia.org/wiki/Virginijus_%C5%A0ik%C5%A1nys#P... Edit: The Nobel award paper writes this on his findings: https://www.nobelprize.org/uploads/2…

Why is academia (at least in the physical sciences) so competitive? My partner is a molecular biologist and she can't collaborate with anyone outside of her lab because of the fear that they collaborators will take their research before they get a chance to publish it. It seems this method of performing groundbreaking research and science is horrifically detrimental to our collective progress. There's no reason for t…

Well, and what about Francis Mojica who discovered CRISPR in bacteria?! He certainly deserved at least 1/3 of the award.
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