I'm sure anyone here who has set up a PiHole ad-blocking DNS server at home has run into these random domain requests and wondered what was going on. At first I thought one of my devices had a virus on it or something until I did a few searches and discovered it was Chrome being ludicrous. (Next topic: Getting Chrome to actually use the DNS provider that you specify and nothing else...)
Would these have occurred on a sever that has unbound as its upstream?
Chrome doesn't care what DNS server software is in use (even if it could figure that out), it cares whether it's behaving properly or not.