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This is truly amazing work, and I hope they are able to achieve their goals. The future of humanity depends on it. If you want to help, they need someone to crack a rar file containing the Chematica data (which was acquired by Merck pharmaceuticals) https://twitter.com/MichaelSLaufer/status/102263726560276889...
>After Four Thieves synthesized cabotegravir, it was just a matter of convincing at-risk populations to use it. According to Laufer, some Four Thieves affiliates began partnering with heroin dealers to cut their product with the cabotegravir.
I know nothing about chemistry/medicine, but this seems stupidly dangerous. There are good reasons to be patient and wait for drugs to go through the phase trials.
It also seems stupidly dangerous to allow uneducated/untrained people to make their own drugs at home by following directions. What if they unknowingly miss a step? For instance, the article is stating that opioids are needed to create Naloxone. That would be a costly mistake to make. They should never release this particular recipe.
These are truly brilliant people who probably have not spent a lot of time hanging around the average person. One reason governments and systems are in place is to prevent the non-well-rounded geniuses from giving an untrained mind an opportunity to make a devastating mistake.
EDIT: This reminds me of the guy who attempted to develop a nuclear reactor in his parents shed. https://en.wikipedia.org/wiki/David_Hahn
> “...the price of Daraprim hasn’t changed,” he said. He reached into his pocket and produced a handful of white pills. “I guess I better hand out some more,” Laufer said as he tossed the Daraprim into the audience. I found it hard to keep reading after that. What's it called when people get so emotional about a cause they just start acting irrationally and doing more harm than good?
> “...the price of Daraprim hasn’t changed,” he said. He reached into his pocket and produced a handful of white pills. “I guess I better hand out some more,” Laufer said as he tossed the Daraprim into the audience. I found it hard to keep reading after that. What's it called when people get so emotional about a cause they just start acting irrationally and doing more harm than good?
I'm not sure I understand what harm was done here?
In the long term, bring drugs to people without thorough testing and regulations. It's one thing for e.g. stage 4 cancer. It's another to let a Vioxx get through.
Strict regulations around the development and testing of drugs exist because no human is capable of evaluating efficacy for themselves, absent stringently controlled testing processes.
We laugh about "snake oil salesmen", but given the amount of money in nutriceuticals, GNC, and the like... I'd say the only damn holding back the torrent on the unsuspecting is the FDA.
> After a few minutes of gloating about pharma bro Martin Shkreli “rotting at Fort Dix” for raising the price of Daraprim Except that’s totally unrelated to why he’s in prison.
Yeah, and Al Capone just went to jail for "tax evasion"...
He brought attention to his tax evasion for other reasons... but is it difficult to acknowledge that the direct legal cause of his jail time was evasion?
> “...the price of Daraprim hasn’t changed,” he said. He reached into his pocket and produced a handful of white pills. “I guess I better hand out some more,” Laufer said as he tossed the Daraprim into the audience. I found it hard to keep reading after that. What's it called when people get so emotional about a cause they just start acting irrationally and doing more harm than good?
I'm not sure I understand what harm was done here?
>Although the initial clinical results with cabotegravir were extremely promising, Four Thieves grew impatient with waiting for it to become commercially available. (The drug is currently undergoing Phase III FDA trials, which means it’s being clinically tested on a large cohort of human subjects.) >After Four Thieves synthesized cabotegravir, it was just a matter of convincing at-risk populations to use it. Accordin…
Making the drug and trying it on yourself is one thing. Sharing it with someone else who understands you and how you made it is somewhat similar. Convincing random people who don't know you to take it is crossing some sort of line, and setting up a situation where people are taking your homemade version of a non approved medication without even knowing it is just plain wrong. I know they are already taking heroin, but these are still people and not your lab rats. You shouldn't be making their decisions for them about what goes in their body.
In their do it yourself lab, what are they doing to remove stereoisomers?
Earlier quoted context omitted.
Yeah, and Al Capone just went to jail for "tax evasion"...
He did go to jail for that, unless I'm confused. He brought attention to his tax evasion for other reasons... but is it difficult to acknowledge that the direct legal cause of his jail time was evasion?
This was true years ago but not anymore. CVS sells a generic epipen two-pack for $109 [1]. Still not cheap, but let’s not pretend that these cost $300 and are not even available. I wanted to like this article but when I read this it made me think either reading journalist didn’t check his facts or is more invested in the narrative than reality.
1: https://www.cvs.com/content/epipen-alternative
Edit: I posted this even though I figured it would attract downvotes. I’m curious if downvoters think my claims are untrue or don’t like the way I’ve phrased my comment.
To me, an article I can’t trust is basically worthless, which is why I pointed these inaccurate facts out.