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Why I’m Digging Deep Into Alzheimer’s

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Re: Why I’m Digging Deep Into Alzheimer’s

#61

Post by bitL »

bshimmin wrote: post #52
bitL wrote: post #48

FYI, taking sauna 4x a week seems to lower the risk of developing Alzheimer significantly (at least in Finland). I can also observe myself that taking hot phase 4-5x for 10-15 minutes followed by 2 minutes cold immersion every time in roughly 1.5 hours clears my brain/senses. Maybe the sweating helps overloaded brain drainage as well? I think Bezos must be applying some of these hacks on himself; he got recently in s…

Bill might think about the same as he is visibly deteriorating and his liver seems to be not functioning well (spots on his skin everywhere) I think he's always had freckles, no?

If you see some recent unedited footage of him speaking, it got much worse. I personally know one soon-to-be-a-billionaire that is heavily funding his own biotech/longevity research to buy more time, yet is hopelessly out of shape and doesn't have the same discipline on his own body he has for his companies. It's paradoxical when you think about it, kinda broken feedback loop.

Re: Why I’m Digging Deep Into Alzheimer’s

#62

Post by freeflight »

Filligree wrote: post #27
freeflight wrote: post #24

Earlier quoted context omitted.

Parent merely stated that we are already over-consuming with rather high death rates, not having any deaths at all most certainly wouldn't help with our current unsustainable ways, as we'd most likely overpopulate the planet pretty quickly with all it's resulting woes (even more pollution, killing off the rest of the biosphere). Imho it'd only work the other way around: For us to beat death, we first have to solve ou…

You're making the mistake of changing one parameter, but not projecting the entire world forwards. Immortality would be impossible without massive technological improvements that certainly would have other benefits; you can pretty well assume that both molecular nanotechnology and genetic engineering will be mature by then. In combination, those should dramatically increase the carrying capacity of the world. Ignorin…

> You're making the mistake of changing one parameter, but not projecting the entire world forwards.

I changed only one parameter, while your assumption changes a whole lot of them in a very optimistic way. Which model do you think is more realistic?

> Don't you think it's likely that people will start caring more about the future onceb they know they'll live to see it?

Eh, imho people are too diverse for anything universal like that. Might as well pose the question if life actually still has meaning without death? If there's no end, how do we define the beginning and the different phases that used to be in-between?

Those kinds of questions would probably be way more relevant than "Let's all apply some foresight, now that we don't actually need it anymore due to being immortal!".

Re: Why I’m Digging Deep Into Alzheimer’s

#63

Post by gk1 »

Even younger people can be afflicted with Alzheimer's (called Early-onset Alzheimer's), and it's even more terrible to witness. It's one thing to watch a human mentally deteriorate when they are at the end of their life, it's another thing to watch it happen to someone in their 40's—who should be in the prime of their life and raising their children.

Re: Why I’m Digging Deep Into Alzheimer’s

#64

Post by edanm »

pmelendez wrote: post #16
Filligree wrote: post #15

Earlier quoted context omitted.

The reason doesn't really matter, this is still incredibly valuable work. Death is terrible, and should be eradicated, but Alzheimer's is a few steps above that. There's nothing worse than seeing a loved one be slowly destroyed by that horrific disease, and I'm so glad there are people willing to work on it.

"Death is terrible, and should be eradicated" We are sensitive to death but it is the only mechanism I know that would control overconsumption of natural resources. If nobody dies, then we would deplete the resources in a few decades.

These are hard problems.

The worst solution we can come up with is to literally kill everyone. We can find a better way.

Re: Why I’m Digging Deep Into Alzheimer’s

#65

Post by melling »

coldtea wrote: post #44
Filligree wrote: post #27

Earlier quoted context omitted.

You're making the mistake of changing one parameter, but not projecting the entire world forwards. Immortality would be impossible without massive technological improvements that certainly would have other benefits; you can pretty well assume that both molecular nanotechnology and genetic engineering will be mature by then. In combination, those should dramatically increase the carrying capacity of the world. Ignorin…

> Immortality would be impossible without massive technological improvements that certainly would have other benefits; you can pretty well assume that both molecular nanotechnology and genetic engineering will be mature by then. I don't think we'll see anything like increased exponential progress of the kind that has been (and has already slowed down) during the industrial age. All low hanging fruit have been gathere…

Then we probably won’t cure death without large technological improvements. Problem solved.

This conversation is going in circles. Has anyone brought up “death gives life meaning”?

https://h4labs.wordpress.com/2017/03/28/stories-that-should-...

Re: Why I’m Digging Deep Into Alzheimer’s

#66

Post by folli »

pmelendez wrote: post #16
Filligree wrote: post #15

Earlier quoted context omitted.

The reason doesn't really matter, this is still incredibly valuable work. Death is terrible, and should be eradicated, but Alzheimer's is a few steps above that. There's nothing worse than seeing a loved one be slowly destroyed by that horrific disease, and I'm so glad there are people willing to work on it.

"Death is terrible, and should be eradicated" We are sensitive to death but it is the only mechanism I know that would control overconsumption of natural resources. If nobody dies, then we would deplete the resources in a few decades.

I'd rather willingly visit Futurama's suicide booth than slowly deteriorate due to Alzheimer's.

Re: Why I’m Digging Deep Into Alzheimer’s

#67

Post by autonomy77 »

gk1 wrote: post #63

Even younger people can be afflicted with Alzheimer's (called Early-onset Alzheimer's), and it's even more terrible to witness. It's one thing to watch a human mentally deteriorate when they are at the end of their life, it's another thing to watch it happen to someone in their 40's—who should be in the prime of their life and raising their children.

>>It's one thing to watch a human mentally deteriorate when they are at the end of their lifeAlzheimers is terrible to witness at any age - the elderly included. While it's certainly tragic to see in younger people, it's no less tragic to see older people in a state of fear and panic, when they should be enjoying their twilight years.

Re: Why I’m Digging Deep Into Alzheimer’s

#68

Post by yeukhon »

gk1 wrote: post #63

Even younger people can be afflicted with Alzheimer's (called Early-onset Alzheimer's), and it's even more terrible to witness. It's one thing to watch a human mentally deteriorate when they are at the end of their life, it's another thing to watch it happen to someone in their 40's—who should be in the prime of their life and raising their children.

Yes. The thing is once you are an Alzheimer's patient, you are doomed because your brain basically stop being able to function at the very end. It's like a death kiss from the above. Unlike cancer, which is scary as hell, and has a high death rate, has better chance of surviving. The pressure on Alzheimer's patient and on the family is just unbearable. While there are some treatments to slow down the progress, we are far from understanding the disease itself, let alone knows how to combat the plaque and tangles effectively. Right now I think one of the best treatments is let patients be more active, whether it's playing chess or gardening, while receiving family support. The more positive we are the better we are overall health wise. This is evident in patients who suffered depression.

Re: Why I’m Digging Deep Into Alzheimer’s

#69

Post by tallanvor »

bitL wrote: post #48

FYI, taking sauna 4x a week seems to lower the risk of developing Alzheimer significantly (at least in Finland). I can also observe myself that taking hot phase 4-5x for 10-15 minutes followed by 2 minutes cold immersion every time in roughly 1.5 hours clears my brain/senses. Maybe the sweating helps overloaded brain drainage as well? I think Bezos must be applying some of these hacks on himself; he got recently in s…

Liver spots are the result of aging sun exposure. A long time ago they were thought to indicate an issue with the liver, but there is no connection between the two. They are not at all an indicator of health. The only affect they have medically is that they can make it harder to detect skin cancer when doing a visual exam.

Re: Why I’m Digging Deep Into Alzheimer’s

#70

Post by pyreton »

taf2 wrote: post #22
bflesch wrote: post #20

It's great to see more investment into this disease. When my grandma fought Alzheimer's over the span of a decade it was very striking to see that the effect of a lack of hydration and the disease itself kind of overlapped. When she had a particularly bad day we used to give her a saline IV and you could immediately notice how she cleared up and regained her brain powers after each IV. I'm not up to date on current r…

I think the toilet in general could use an upgrade... for how many years have they been built exactly the same way? Has anyone ever done a study of the flow as urine impacts the toilet and bounces back? Or as we learn more about the importance of stomach bacteria, can our toilet start to do more monitoring of the bacteria in our stomach? Love your idea of hydration monitoring and think the application is probably mor…

Here's an article on "Smart Toilets": https://singularityhub.com/2009/05/12/smart-toilets-doctors-...
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