Earlier quoted context omitted.
Is that time a typo? Are you saying that there is only a 5 hour block of the day when you eat? (From 3pm to 8pm.)
Correct. That's what IF means.
^ IF == Intermittent Fasting
Aspirin May Prevent Cancer from Spreading, New Research Shows
61–70 of 122 posts
Re: Aspirin May Prevent Cancer from Spreading, New Research Shows
#62Earlier quoted context omitted.
Even a small amount of Asprin, if taken regularly, will mess up your stomach in my experience! I guess not everyone is sensitive to it, but for me I've avoided Asprin (and Ibuprofen, another NSAID drug) for years because of this.
What's 'regular?' I use ibprufen exclusively, without stomach issues. But not daily. I probably take it once per week on average. Usually when lacking caffeine has caused a headache. Or eyestrain, occasionally. Those are probably the issues I should fix, though.
In the peak of my "strenuous exercise" and "age" graph, I was taking about 12 advil a day, with Zantac. Eventually that, combined with a bit too much drinking (0-3 drinks a day), culminated in a messed up stomach. But I easily can go 2-4 advil a day without a problem. I avoid it, these days, and typically take 1 or 2 every day or two.
In the military, "Vitamin M" (800mg of motrin/ibuprofen, about 4 advil) used to be heavily given for about anything multiple times per day!
Re: Aspirin May Prevent Cancer from Spreading, New Research Shows
#63Talking about simply accessible products, anybody has knowledge about cannabinoids (specifically cannabidiol, not THC) ?
I've dug as deep as I could from someone out of a lab and found tons of evidence, but the issue is that doctors have each a different point of view on it. So far I got:
- it's innocuous but help opioids for pain
- it's potentially antitumoral but human studies are lacking [0]
- it's been studied and discarded because useless [1]
- cannabis derivatives are toxic [2]
- what's cannibidiol ? oh USA use that, Europe lags behind, I'll see
[1] renowned oncologist opinion, yet so many research on cannabidiol still going ? odd
[2] so far I've yet to find more than one paper listing toxicity (except one talking about accidental overdose on that one hypersensitive person that used her daughter's provider)
I'll take any info just in case.
Re: Aspirin May Prevent Cancer from Spreading, New Research Shows
#64Earlier quoted context omitted.
Even a small amount of Asprin, if taken regularly, will mess up your stomach in my experience! I guess not everyone is sensitive to it, but for me I've avoided Asprin (and Ibuprofen, another NSAID drug) for years because of this.
Given the doctors seem to be telling everyone over 50 to take a daily aspirin, I would think that a goodly chunk of people aren't sensitive. It might be the low dose people are taking.
It's also possible that the heart benefits outweigh the side effects. A lot of medicine is just saying "this sucks but if you don't do it you'll die" and prescribing the least bad option.
Re: Aspirin May Prevent Cancer from Spreading, New Research Shows
#65Earlier quoted context omitted.
What's 'regular?' I use ibprufen exclusively, without stomach issues. But not daily. I probably take it once per week on average. Usually when lacking caffeine has caused a headache. Or eyestrain, occasionally. Those are probably the issues I should fix, though.
In the peak of my "strenuous exercise" and "age" graph, I was taking about 12 advil a day, with Zantac. Eventually that, combined with a bit too much drinking (0-3 drinks a day), culminated in a messed up stomach. But I easily can go 2-4 advil a day without a problem. I avoid it, these days, and typically take 1 or 2 every day or two. In the military, "Vitamin M" (800mg of motrin/ibuprofen, about 4 advil) used to be…
That's a bit scary. Chronic use of NSAIDs has been associated with kidney cancer, and if that doesn't scare you, erectile dysfunction may, if you're a man. I'd go with Tylenol instead (carefully), although that has pretty serious liver risks too.
Re: Aspirin May Prevent Cancer from Spreading, New Research Shows
#66Earlier quoted context omitted.
I would go out on a limb and say it's a LOT of Asprin. I usually use "surprising" on HN because anything more specific gets criticized surprisingly often, but that is a ton of asprin
it's a veritable fuck-ton. the usual modern dose is 325mg.
The maximum daily dose is usually around 4g. 325mg is probably the dose in one tablet.
Re: Aspirin May Prevent Cancer from Spreading, New Research Shows
#67Earlier quoted context omitted.
Acetaminophen in particular is somewhat scary. Just 2.5x the recommended maximal daily dose of 4g can lead to complete liver failure. With alcohol, other medication, or existing damage, much less could be enough.
It's arguable that Acetaminophen shouldn't be an OTC drug. And that, had its liver toxicity been fully understood, it probably wouldn't be. At the time, it apparently seemed a good alternative to aspirin which does cause some number of people to have stomach problems. (As well as having a particularly extensive repertoire of only somewhat understood physiological effects, for better or worse.)
And aspirin should never be used in children because its use in children is associated with Reye syndrome.
Re: Aspirin May Prevent Cancer from Spreading, New Research Shows
#68Talking about simply accessible products, anybody has knowledge about cannabinoids (specifically cannabidiol, not THC) ? I've dug as deep as I could from someone out of a lab and found tons of evidence, but the issue is that doctors have each a different point of view on it. So far I got: - it's innocuous but help opioids for pain - it's potentially antitumoral but human studies are lacking [0] - it's been studied an…
Sorry haven't got much time at the moment, here's the paper that got me interested
Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
http://www.nature.com/nm/journal/v6/n3/abs/nm0300_313.html
Put that into Google Scholar (the paper title or just "guzman thc"), then click on the Cited by xxx below in the search results to find newer papers.
GW Pharma is a company doing clinical trials, and i think Canadian licenced producers of cannabis are doing trials as well (though i don't know how many are about cancer/anti-tumoral activity).
Here's a long list of research papers on cannabinoids:
Re: Aspirin May Prevent Cancer from Spreading, New Research Shows
#69Earlier quoted context omitted.
I've fasted from ~8P to ~3P every day for coming up on 2 years and apart from making me more mindful of what I eat and drastically reducing my appetite I've experienced basically no other health benefits. IF is increasingly well studied and it is not especially amazing. (I like it a lot. Just saying.)
Is that time a typo? Are you saying that there is only a 5 hour block of the day when you eat? (From 3pm to 8pm.)
I'm not the person you replied to but I'll churp in. I only eat once a day, at dinner time, so I eat in about a half hour block a day. I've been doing it for years. It's not really that odd once you get used to it. My appetite and food consumption has decreased dramatically and I am full much quicker. My food bill has decreased and it's very, very freeing to only have to worry about eating once a day. It's absolutely amazing for me though certainly not for everyone.
Re: Aspirin May Prevent Cancer from Spreading, New Research Shows
#70Talking about simply accessible products, anybody has knowledge about cannabinoids (specifically cannabidiol, not THC) ? I've dug as deep as I could from someone out of a lab and found tons of evidence, but the issue is that doctors have each a different point of view on it. So far I got: - it's innocuous but help opioids for pain - it's potentially antitumoral but human studies are lacking [0] - it's been studied an…
Sorry haven't got much time at the moment, here's the paper that got me interested Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation http://www.nature.com/nm/journal/v6/n3/abs/nm0300_313.html Put that into Google Scholar (the paper title or just "guzman thc"), then click on the Cited by xxx below in the search results to find newer…
Oh I know that, I mailed Cristina Sanchez about her research. I looked for the GW trial (brain metastasis IIRC) in UK but so far couldn't find any results.
thanks for the other link, I never looked at that website before.
ps: and to add to the theories, Desprez cbd research hints at ID-1 transcription regulation; ID-1 appearing to be a embryogenic-time gene, turning cells into highly mobile and differentiating regime => aggressive tumor. If CBD does interfere with ID-1 expression, it's not implausible that tumors grow much more slowly and locally, which is probably always good.
pps: one more thing, cbd and cannabinoids have a huge image problem; people just dismiss it as hippie shit.