Earlier quoted context omitted.
It's really time to start distributing ES6 via npm. All current browsers support ES6. It's now generally faster than equivalent ES5, it minifies better, tooling is better, etc. It's the app that should compile all the code to run in the target environment if needed. This is what we've done in the new Polymer CLI / polymer-build: we compile all dependencies but only if necessary.
I agree that this is the future. But that will mean telling everyone that they should now run their node_modules through Babel - no inconsequential feat, given the size of the code that must now be transpiled.
Messy.