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Covid vaccine: First ‘milestone’ vaccine offers 90% protection

bbc.co.uk

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Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#592

I'm feeling a deep-seated wave of relief that I never thought possible. Like waking up from a year-long nightmare. Thank God.

> Thank God. God also gave us this virus, if we stick to the religious logic.

I thought it was bush meat. So human decided to eat something that they shouldn't. Geniuinly asking.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#593
post #17

Seems like a good time to buy shares in whoever manufactures industrial sized extra cold freezers.

Dry ice manufacturers may be a better bet. Hard to change -70C/-80C freezer manufacturing capacity, but pretty easy to pump out more dry ice or LN2 for storage.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#596
post #584

Good: + ~90% of individuals achieve immunity. + no significant side-effects. Not so good: - two doses needed, 3 weeks apart, immunity after one month from first dose. Slow rollout. - -80C storage and transport needed. Challenging, but doable in developed countries, but still may slow down mass rollout. Not feasible in many developing countries. I still wonder about long-term immunity. Anyone can share any insight?

Also bad: What did they use to stabilize the mRNA? If they’re managing to do it with just temperature and maybe glycerol, that’s great. If it’s RNAlater, then that’s going to have safety issues. If it’s something else, how was the additive tested for long term safety? (Vaccines like this have been in the works for a long time. There has been time for safety studies.) Edit: RNAlater MSDS sheet: https://tools.thermofis…

What is wrong with RNAlater? Seems like it is just EDTA and Sodium Citrate and Ammonium Sulfate.

https://www.protocols.io/view/RNAlater-Recipe-c56y9d

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#597

Earlier quoted context omitted.

I think we can eradicate it by contact tracing. With 90% efficiency it will be extremely tough for the virus to spread. For any new cases you simply test everyone in the vicinity of the infected person. But I don't think even that will be necessary. 90% efficiency reduces R so much, it will probably die out on its own. The real problem is mutations that are not covered by the vaccine. If it mutates as efficiently as…

I haven't seen much chatter about it, but this will only be prescribed for adults (18+) correct?

Yes, and only/primarily/first at-risk groups, incl. at risk to themselves or others because of workplace in healthcare/residential home/etc. - but nothing firm I don't think.

https://www.gov.uk/government/publications/priority-groups-f...

We're still months away from all 20M (of a >60M population) people that vaccines have been ordered for being administered with them, (BBC reports 'up to' 10M doses 'may' be 'delivered' this year, i.e. 5M people max) so I suppose they still have plenty of time to decide the most effective pecking order.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#598

Earlier quoted context omitted.

They're already manufacturing millions of doses of the drug and have been for months. The military already has an action plan for distributing it nation wide. Realistically they're ready to go right now they are just waiting for FDA approval.

Lol you vastly overestimate the capabilities of the US Gov and Military. I wouldn't be remotely surprised if you can't get a dose if you want one until well into 2021.

The US military is (to make up a number) 85% logistics. Supply chain management is the one thing they absolutely excel at. We can move troops and keep them supplied even in the most remote, most dangerous areas of the world. It's what the military does.

What makes you say this, other than a knee-jerk 'US-bad'?

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#600

I'm feeling a deep-seated wave of relief that I never thought possible. Like waking up from a year-long nightmare. Thank God.

This is not a panacea, it will still take time to fully vet the data and it will likely be months before doses start going out and even more months after that until sufficiently large numbers of people have been inoculated before we can even approach normality.

"it will likely be months before doses start going"

Where do you get that it will take "months" between emergency approval and actual vaccinations? The communications out of the leading vaccine teams clearly state otherwise.

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