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GLP-1s are breaking life insurance

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Re: GLP-1s are breaking life insurance

#551

Post by jtrn »

geye1234 wrote: post #546
jtrn wrote: post #536

Earlier quoted context omitted.

Reminds me of a client I had once. He said that the only thing that made him reset was to "pig out" with a carb-overdose, then just sit in front of the TV with a sugar high. Incidentally, I had been nagging him about trying ANYTHING (in addition to the therapy we were doing to find a life goal he believes in) that might help him get SOME help. Be it Adderall or Ozempic. But people are complex, and at best, a person i…

Do you have any thoughts on GLP-1s for ADHD? I have tried the stimulants (legally) without success, and am reluctant to try the non-stimulants since their success rate seems pretty poor and side effects seem worse.

I answered it a couple of places in this thread already, but the short answer is yes, and GLP1 is not usually a good way to core ADHD treatment.

However, if you tried stimulants without success, this would be my descending list of things that need to be sorted out:

- Have you tried multiple types of medication? A lot of people give up after 1 or 2 different types. But I have seen MANY people who get completely new lives, but only after the 5th type they tried that matched their biology. - Do a diagnostic re-evaluation to make sure that one is not misdiagnosing ADHD (the most common confusion is anxiety and personality). - Map out the life situation. Circumstances might be a stronger explanation of the situation than internal psychological vulnerabilities. - Make sure that you get a blood-mirror (Norwegian concept) so you know you have proper absorption/amount in blood.

Re: GLP-1s are breaking life insurance

#552

Post by jtrn »

glp1guide wrote: post #273
jtrn wrote: post #226

Earlier quoted context omitted.

For semaglutide, the newest and most potent GLP1. United States: The main patent is expected to expire around 2032. Monthly Price: $950 - $1,350+ (cash price without insurance) Norway: The main patent is expected to expire around 2031. Monthly Price: $109 - $301 (cash price equivalent in USD)

> For semaglutide, the newest and most potent GLP1. Tirzepatide is the most potent GLP1 https://glp1.guide/content/semaglutide-vs-tirzepatide-clinic...

This is where I failed as a psychologist because I don't have extensive training in pharmacodynamics, so I forgot that "potent" is a specific term in that world. What I meant was: I subjectively believe that Semaglutide is the best choice for weight loss, given the overall profile and response in my subjective clinical experience.

A fancy way of saying: I *think* Semaglutide is best.

Re: GLP-1s are breaking life insurance

#554

Post by glp1guide »

jtrn wrote: post #552
glp1guide wrote: post #273

Earlier quoted context omitted.

> For semaglutide, the newest and most potent GLP1. Tirzepatide is the most potent GLP1 https://glp1.guide/content/semaglutide-vs-tirzepatide-clinic...

This is where I failed as a psychologist because I don't have extensive training in pharmacodynamics, so I forgot that "potent" is a specific term in that world. What I meant was: I subjectively believe that Semaglutide is the best choice for weight loss, given the overall profile and response in my subjective clinical experience. A fancy way of saying: I *think* Semaglutide is best.

Ah -- the linked research trial contains evidence that it is not the best, Tirzepatide is more effective.

Unless you mean that Semaglutide worked best for you, right now the research points at Tirzepatide being most effective for weight loss (says nothing about t2d though).

Re: GLP-1s are breaking life insurance

#555

Post by gangstead »

helicalmix wrote: post #484
altcognito wrote: post #323

Earlier quoted context omitted.

If you were guaranteed 5% over the total cost of the medical services provided as profit, would you want people to have expensive or cheap medical. Are?

can you explain this statement to me more? I think i'm missing something

The health insurance companies are paid as a percentage of the amount of care that flows through them. So healthier customers means their profit is 5% of SMALLER_NUMBER.

Re: GLP-1s are breaking life insurance

#556

Post by glp1guide »

hippich wrote: post #427
glp1guide wrote: post #273

Earlier quoted context omitted.

> For semaglutide, the newest and most potent GLP1. Tirzepatide is the most potent GLP1 https://glp1.guide/content/semaglutide-vs-tirzepatide-clinic...

Can't find the post on Reddit right now, but someone broke all three down and it is more nuanced. They act slightly differently in different areas. Before I started experiments on "my lab rat" with retatrutide, I found that combination of the about half max dose of semaglutide and 1/3 of Max dose of tirzepatide had the best combination of losing weight and lowering side effects. But another "lab rat" did not respond…

Retatrutide looks to be very effective, but it's not possible to get legally/safely at this point. TONS of experience/knowledge in the r/retatrutide subreddit though, a lot of pretty conscientious consumers in there that have done their research, but obviously impossible to recommend outside of finding a sanctioned study to join.

That said, Reta is a triple agonist[0] and it seems to be quite amazing with good muscle retention as well -- it's unclear if this is just the people who are taking it being more likely to be gym goers. Up until now the only formulation I've seen that specifically targets preserving muscle is GLP1s in combination with bimagrumab[1].

[0]: https://glp1.guide/content/a-new-glp1-retatrutide/

[1]: https://glp1.guide/content/preserving-muscle-glp1s-with-bima...

Re: GLP-1s are breaking life insurance

#557

Post by mattmanser »

Auracle wrote: post #362
mattmanser wrote: post #88

Earlier quoted context omitted.

There's often side effects, including nausea, diarrhea, headaches, bloating, discomfort, etc. As far as I can tell from forums, it's not like 5% have the side effects, it's like 80-90%. But for the first time in decades, I felt full. I didn't want to finish a meal, it was too much. My body regulated my food intake in what felt like a natural way. I hadn't even realized my body had somehow lost that fundamental mechan…

I’m sorry, but as one of the rare (decently) fit & nondiabetic people that have taken these drugs I’m going to call out your comment a bit. While I have no doubt that obese people have gradually made appetite control harder for themselves, the full feeling you get on GLP meds is in no way the way us normal-weight people feel. I too, could easy eat a whole bag of doritos after some pizza and then decide I want ice cre…

What's with the body shaming mate?

I literally have no feeling of 'full'. I used to. I have no idea when it stopped working, but it definitely stopped working.

You can't know what I feel. I can't know what you feel. I'm fit, I have zero appetite control.

If I stop doing tons of exercise, boom, problems. I got old, I stopped moving as much, boom, problems.

People like you are part of the problem, not the solution.

Honestly, you wouldn't say this shit to someone's face.

It was honestly hard enough posting this here in the first place and then a dick like you comes along.

Cheers thanks for ruining my day you prat.

Re: GLP-1s are breaking life insurance

#558

Post by freeplay »

Spivak wrote: post #528
freeplay wrote: post #513

Earlier quoted context omitted.

"We've tried nothing and we're all out of ideas" The obesity trend has happened almost in lockstep with the proliferation of highly processed foods. Butter and animal fats being replaced with low quality, hydrogenated vegetable oils. Cane sugar being replaced with high fructose corn syrup and other highly processed sweeteners. Sodas and sugary juices replacing water. Food like substances with little to no nutritional…

I agree with every word of your analysis and I agree that we've tried basically nothing. But this is why I talked about political capital—every one of your suggestions has been available for the last twenty years and nothing has come of it and the problem continues to get worse. When you say something like, "healthy food should be more affordable and readily available" you'll get a lot of nods of agreement but when i…

> healthy food should be more affordable and readily available

I think there's more than one way to achieve that. It doesn't have to be bans or subsidies. A lot of it has to do with education and competition. Unfortunately, they are kind of a circular dependency.

- There's so much cheap, highly processed food out there. The companies pay for prime real estate on the shelves and expensive marketing. It is chemically engineered to exploit your pleasure senses when you eat it. That is a hard beast to fight without proper education. And not just the food pyramid, but in depth explanations on why you should avoid it and what to eat instead. There are large groups of the population that have no idea that pop tart or cereal are not a healthy breakfast option.

- If there were more companies creating and promoting healthy, less-processed food options, the price would naturally comedown due to competition. But without the education, these products just do not sell as well. If I gave you some natural peanut butter or almond butter (just almonds or peanuts - 1 ingredient) and I gave you a jar of a more common peanut butter like JIF (sugar + hydrogenated oil for better consistency) and you had no other information at all, you're choosing JIF 10 out of 10 times. It's cheaper, it taste better, and you don't have to stir it. These megacorps prey on that lack of knowledge.

More education -> make better choices when buying -> more companies selling those choices -> cheaper prices on those choices.

Re: GLP-1s are breaking life insurance

#559

Post by SirMaster »

unethical_ban wrote: post #502
SirMaster wrote: post #476

Earlier quoted context omitted.

You think that controlling your anxiety and controlling what you put into your mouth are equal things? I would say that controlling what you put into your mouth is easier than controlling your anxiety.

When "putting something in your mouth" is the result of a mental component, is there a difference?

I think there is a big difference when one still ultimately requires a physical act in the end and one is all mental.

You can much more easily use the physicality of your surroundings to physically deny yourself the food than you can deny yourself anxious thoughts.

With eating there are 2 components to it, mental and physical, so you have more opportunities and more options and avenues to potentially control it.

The additional options to control it should IMO make it at least some amount easier to control in the end since some people may be able to take advantage of physical controls to limit themselves where that's not an option for anxiety.

Re: GLP-1s are breaking life insurance

#560

Post by cindyllm »

jtrn wrote: post #536
joncrane wrote: post #459

Earlier quoted context omitted.

I believe you 100%. I have a history of substance abuse with bad consequences. I quit alcohol and now my drug is food. People tell me I'm a "supertaster." I can taste many of the ingredients in my food that others can't. I also have BPD and am in therapy for it, but man. Food is the drug that always works. When I get into a certain mode, it's like I don't care that I'm overweight and have high blood pressure. I just…

Reminds me of a client I had once. He said that the only thing that made him reset was to "pig out" with a carb-overdose, then just sit in front of the TV with a sugar high. Incidentally, I had been nagging him about trying ANYTHING (in addition to the therapy we were doing to find a life goal he believes in) that might help him get SOME help. Be it Adderall or Ozempic. But people are complex, and at best, a person i…

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