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GLP-1 drugs: An economic disruptor? (2024)

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Re: GLP-1 drugs: An economic disruptor? (2024)

#511

Post by davoneus »

crazygringo wrote: post #371
Etheryte wrote: post #298

Earlier quoted context omitted.

Many foods and beverages include ingredients whose sole purpose is to hide how sweet it is because otherwise it would be unbearable in your mouth. Gives you a stronger high once it reaches your stomach though.

I don't know where you got that information, but no they don't. That's not a thing. You were misinformed.

No, you're the one in denial. Just have a look at the decade old book "Salt Sugar Fat: How the Food Giants Hooked Us" to see the flaw in your assumptions.

It details many Concrete examples of exactly how the companies are manipulating everything about food for profit.

Kessler, further FDA head has written about this topic extensively as well.

Re: GLP-1 drugs: An economic disruptor? (2024)

#513

Post by thefz »

cj wrote: post #19

I started Tirzepatide 3-4 weeks ago. (Mostly as an experiment to understand the hype around GLP's... I don't have diabetes and only very slightly overweight at 20% body fat). Even at the lowest 2.5mg starter dose which you're only allowed to stay on for 1 month: - Extreme appetite suppression to the point where I've started calorie counting specifically to make sure that I'm eating enough. It's incredibly easy to for…

> After a few weeks on the drug, I'm 100% convinced that once this drug is widely available and cheap... being overweight will be a choice

It already is.

Re: GLP-1 drugs: An economic disruptor? (2024)

#514

Post by toomuchtodo »

akutlay wrote: post #508
toomuchtodo wrote: post #368

Earlier quoted context omitted.

https://data.worldobesity.org/rankings/ https://www.who.int/activities/controlling-the-global-obesit... The US isn’t even the top 9. Obesity is a global epidemic of Western disease. The food isn’t the cause, it’s the symptom of the brain chemistry. If it isn’t available, yes, the disease may not present. But if available, due to hormones causing the drive , it presents. Like cigarettes (nicotine), like cocaine, like…

All the countries above US have less than 1M population and generally poor countries. Saying that obesity is not related to the underlying social problems in the US showing this data is ridiculous.

https://en.wikipedia.org/wiki/Obesity_in_China

https://en.wikipedia.org/wiki/Obesity_in_India

Re: GLP-1 drugs: An economic disruptor? (2024)

#515

Post by gcanyon »

machomaster wrote: post #489
gcanyon wrote: post #388

Earlier quoted context omitted.

1. I can't speak to that, no analysis here and the time frame (the low carb thing was back around 2008) is too long for meaningful comparison. 2. Maybe? For normal things, not really, but when I try to row for an hour I feel it. I definitely get cold more easily. 3. I'm not built that way. The low carb thing was completely annoyance-free. As I said, the goal there wasn't weight loss, but raising my HDL; the weight li…

I was answering a general question, not talking about you/diet specifically. It's generally recommended to: - do heavy resistance training - losing fat at the rate of 0.5-1% of a body weight a week - do it for 8-12 weeks - (critical) after which to have a maintenance phase with a duration of 2/3-1 length of the dieting phase - after that can do another dieting phase again. - repeat as many times as needed. - if wishe…

> I was answering a general question, not talking about you/diet specifically.

Sure, I get that, and I responded in the context of my original "I'm going to throw out anecdata" note. In that spirit:

I've generally gone longer than 8-12 weeks, but not by much -- longest is probably 16 weeks?

I've definitely lost more than 1% per week. I don't graph it, but I think I'm hovering in the 1% - 1.5% range.

I'm curious about the maintenance phase and strength aspects -- I'm not interested in bulk, just strength.

Re: GLP-1 drugs: An economic disruptor? (2024)

#516

Post by BeFlatXIII »

rsync wrote: post #28

The real trend is deflation. People are having fewer children. Fewer miles are driven to fewer offices for fewer trips in cars. Fewer impulse buys are being made and fewer dollars will be made by advertisements (according to the ops conjecture). This is not inflationary. It is the opposite. We live in a deeply deflationary world and we should not be confused by the local, transitory inflation that we may be experienc…

All this sounds fantastic for environmental sustainability.

Re: GLP-1 drugs: An economic disruptor? (2024)

#517

Post by cj »

thefz wrote: post #513
cj wrote: post #19

I started Tirzepatide 3-4 weeks ago. (Mostly as an experiment to understand the hype around GLP's... I don't have diabetes and only very slightly overweight at 20% body fat). Even at the lowest 2.5mg starter dose which you're only allowed to stay on for 1 month: - Extreme appetite suppression to the point where I've started calorie counting specifically to make sure that I'm eating enough. It's incredibly easy to for…

> After a few weeks on the drug, I'm 100% convinced that once this drug is widely available and cheap... being overweight will be a choice It already is.

Yes. In the same way addiction is a choice.

Re: GLP-1 drugs: An economic disruptor? (2024)

#518

Post by wakawaka28 »

submeta wrote: post #487
wakawaka28 wrote: post #256

Earlier quoted context omitted.

Yeah it's anti-capitalist rants at every turn around here. Capitalism is the best system we have to make people happy in a fair way. It's not a system to teach people the benefits of moderation or charity. You're supposed to bring that to the table yourself. There's no economic system in the world that can fix character flaws.

Yeah, lets sell cigarettes and blame consumers for health issues because, you know, capitalism is the best system we have and the burden is on the consumers.

The burden IS on consumers though. Tobacco, alcohol, caffeine, sugar, and even bottled water can be harmful in excess. How about video games and porn? I don't think it's the government's job to tell you that you can't have basic things like that just because it might make your health worse in some way if you go crazy with it. Capitalism isn't there to teach you moderation, it's to get you what you want or need efficiently.

Re: GLP-1 drugs: An economic disruptor? (2024)

#519

Post by loeg »

cj wrote: post #77
Judgmentality wrote: post #50

Earlier quoted context omitted.

[flagged]

You can get wegovy generic for $299/mo and Zepbound generic for $399/mo currently through telemedicine via compounding pharmacies, without insurance.

FDA has determined the shortages of the non-compounded versions has been resolved (of zepbound/tizepatide in October 2024, and wegovy/semaglutide last week): https://www.fda.gov/drugs/drug-safety-and-availability/fda-c...

So compounders can no longer legally sell tirzepatide and will soon (April-May) be unable to legally sell semaglutide.

Re: GLP-1 drugs: An economic disruptor? (2024)

#520

Post by loeg »

Henchman21 wrote: post #464
petesergeant wrote: post #452

Earlier quoted context omitted.

Stop moving up the dosage so fast.

I'm under the care of a physician, and my dose is fine, and managed by him, thanks :)

Then I'd encourage raising these concerns with your physician then and asking for a lower dose.
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