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Prozac 'no better than placebo' for treating children with depression, experts

theguardian.com

501–510 of 561 posts

Re: Prozac 'no better than placebo' for treating children with depression, experts

#501

Earlier quoted context omitted.

The discredited procedure that was banned in the Soviet Union before the United States? That was used disproportionately against women? https://en.wikipedia.org/wiki/Lobotomy

well, yes, it did work. the side effects are horrible, and often the disease was better than the cure, but it worked, similar to how being dead also is extremely effective for managing depression.

Murder is a very successful cure to a lot of ailments.

Re: Prozac 'no better than placebo' for treating children with depression, experts

#502

Earlier quoted context omitted.

Because the problem's not a "neurochemistry issue" (that theory's been debunked and the "chemicals" in play have never been known), and the solution is "no better than placebo."

> Because the problem's not a "neurochemistry issue" (that theory's been debunked and the "chemicals" in play have never been known), and the solution is "no better than placebo." It most certainly has not been debunked and mind altering chemicals most certainly do work. SSRIs have _questionable_ efficacy but that's not the same as proven to have none, which is an exceptionally high bar. This is close minded dogma no…

If you don't have a serious model for what you are treating, then you are experimenting on your patients and hoping it works for unknown reasons. Not too different from folk remedies. Even worse, patients are essentially never informed that the doctor is throwing things at the wall hoping something sticks.

Re: Prozac 'no better than placebo' for treating children with depression, experts

#503

Earlier quoted context omitted.

well, yes, it did work. the side effects are horrible, and often the disease was better than the cure, but it worked, similar to how being dead also is extremely effective for managing depression.

Murder is a very successful cure to a lot of ailments.

I feel like you're not getting the very obvious implied point in that no one thinks lobotomy was good practice in retrospect

Re: Prozac 'no better than placebo' for treating children with depression, experts

#504

Earlier quoted context omitted.

the alternative is depression. brain altering drugs seem preferrable

Is that the only alternative?

Therapy is effective, but not always. sometimes, especially with children, there is no root cause in life to the depression beyond "genetics". Additional, therapy may simply be useless and unproductive without medication being used concurrently.

There's also simply death. I didn't feel like mentioning it, but I think its worth pointing out that without treatment, death is a very real possibility.

Re: Prozac 'no better than placebo' for treating children with depression, experts

#505

Earlier quoted context omitted.

This is empirically false; the rates of chronic physical and mental illnesses nowadays are are far higher than e.g. 50 years ago, and these are serious illnesses, not the kind of thing that could have been just not noticed.

That's your opinion, that is not the general opinion of the professionals in the field. I trust a cohort of scientists significantly more than anonymous strangers online, and you should too.

The data is very clear that the rate of mental illnesses is increasing. Rates of severe mental illnesses like Schizophrenia are also increasing.

NONE of the current theories being experimented with on patients have a concrete, proven scientific basis with some such as the decades-long SSRI scam have actively harmed patients and created physical dependence/addiction and actively causing harm to patients and their families (eg, SSRI-induced suicides).

I trust science, but I don't trust scientists any more than I trust any other human with their money, career, and reputation on the line. I trust the FDA and pharmaceutical company ethics even less (eg, Bayer knowingly selling HIV-infested drugs to hemophiliacs, saying Oxycotin is non-addictive, or the revolving door that allows non-working SSRIs to be released and marketed as working despite all evidence to the contrary).

Re: Prozac 'no better than placebo' for treating children with depression, experts

#506

Earlier quoted context omitted.

> my 7-year-old son just started half that dose This is horrifying.

We had/have a lot of reservations about it too, and discussed it at length with our pediatrician over months of observation. We decided what was more horrifying was hearing a 7-year-old — who has supportive family and friends, good health, no traumatic events, no major life changes going on, never worries where food/shelter is coming from — say he feels like "he shouldn't be on Earth anymore" and suddenly react with…

The solution for suicidal thoughts is a drug known to induce suicidal thoughts?

You said elsewhere that there were "no known long-term side effects". Aside from that not being universally true for any drug I've ever personally researched, no side effect is more long-term than suicide.

Re: Prozac 'no better than placebo' for treating children with depression, experts

#507
post #189

Earlier quoted context omitted.

This is one of the most shocking things I have ever read. There is a black box warning for Prozac: ‘Warning: Suicidality and Antidepressant Drugs Increased risk of suicidal thinking and behavior in children, adolescents, and young adults taking antidepressants for Major Depressive Disorder (MDD) and other psychiatric disorders’ Read the package insert: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/01... T…

Note that the black box warning has nothing to do with long-term effects of the medication. It was added specifically because kids were killing themselves within weeks of starting the medication. > This is one of the most shocking things I have ever read. Good grief. I hope you're exaggerating for effect.

> Note that the black box warning has nothing to do with long-term effects of the medication

What are the long-term effects of suicide?

A 7-year-old kid doesn't understand what suicide really means. Putting them on something that encourages a behavior that they don't understand and has completely catastrophic results isn't a risk I would take with my children.

Re: Prozac 'no better than placebo' for treating children with depression, experts

#508
post #231

Earlier quoted context omitted.

Death is a long term effect. And I am not exaggerating. I did not feel the need to list any of the myriad other potential long term effects because death seemed sufficiently serious. Edit: in case the OP is reading, I should say also that the package insert won’t mention many other potential long term effects addressed in the literature, like extra pyramidal symptoms (akathisia, Parkinsonism, dystonia, tardive dyskin…

right which is why they are treating the depression (which leads to suicidal tendencies) which is a symptom of depression, with prozac. that's what the prozac is for. to prevent death

Prozac and other SSRIs are proven to cause MORE suicidal tendencies in children.

Re: Prozac 'no better than placebo' for treating children with depression, experts

#509
post #460

Earlier quoted context omitted.

This is, in fact, pretty much the exact procedure: try one type of treatment or medication, see if it's obviously helping, and if it isn't try a different treatment or medication. It's imprecise but it's the best we have.

The problem is that taking certain psychotropic medications changes your brain chemistry. It’s not as simple as it sounds. It’s not like trying on shoes. The brain is dynamic and drugs alter it, as does life experience, talk therapy, disease, aging, etc…

That’s a statement of fact, but not intrinsically a problem. Being alive changes your brain chemistry.

Re: Prozac 'no better than placebo' for treating children with depression, experts

#510
post #13
post #3

Earlier quoted context omitted.

The problem with suicidal depression is that if someone has created the thought pattern that death is best, then removing the symptoms of depression (lethargy, lack of energy, no willpower) now gives the person the ability to actually follow through with the act. Medications almost always target symptoms and never address root causes.

This is what my psychiatrist more or less warned me about when I went on medication; that a lot of people who are suicidal lack the energy and ability to plan their suicide, and medications can sometimes undo those particular symptoms and people manage to end themselves. I'm not sure what kinds of studies have been done about it, but I've had a few therapists same similar ideas. If it's not a studied phenomenon, then…

This theory is a science-free zone. It seems far more likely that the drug induced sudden, overwhelming suicidal thoughts than someone said "I feel the best I've ever felt and life is looking up. I think I'll kill myself and make all the good feelings go away".

Furthermore, if the latter were true, it would be an indication that depression was a symptom rather than a cause and the psychiatrist misdiagnosed and improperly treated the patient.

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