Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Covid vaccine: First ‘milestone’ vaccine offers 90% protection

bbc.co.uk

Post reply on HN
Print view View original

501–510 of 1001 posts

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#501

Post by corobo »

DanBC wrote: post #437
jakozaur wrote: post #214

Good: + ~90% of individuals achieve immunity. + no significant side-effects. Not so good: - two doses needed, 3 weeks apart, immunity after one month from first dose. Slow rollout. - -80C storage and transport needed. Challenging, but doable in developed countries, but still may slow down mass rollout. Not feasible in many developing countries. I still wonder about long-term immunity. Anyone can share any insight?

Also not so good: this is a corporate press release. The data will come later.

At least this one has a decent looking 'n' value. The BBC also address this in part

> There are still questions - how long does immunity last, does the vaccine work as well in high-risk elderly people, does it stop you spreading the virus or just from developing symptoms?

I'd rate the news as "vibing" on a scale of clickbait to party for the world

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#502

Post by zzbzq »

ploika wrote: post #263
andrepd wrote: post #155

Earlier quoted context omitted.

The markets? Spare me. What are the markets, a handful of rich in banks and large corporations? They are neither wise nor competent, why should every news story be suffixed by how "the markets" (swt) react?

Since you asked, also the pension funds of almost everyone you know.

retirement accounts--pensions are legacy technology

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#503

Post by ahoka »

a_humean wrote: post #84
nsoonhui wrote: post #38

Just curious, why the reaction towards this and the ones from Russia/China are different ?

They have only done phase 1/2 trials and this one is phase 3. Also, people trust US/EU research more. They have not been very forthcoming with data. The data that has been made available has been lacking in detail or has patterns that indicate either fabrication or sloppiness. Both countries appear to be moivated by domestic and geopolitical political purposes. The US has also being doing that, but the medical establ…

"Also, this is a German result, and people trust Germany more."

Like with the diesel emissions?

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#504

Post by m3kw9 »

jakozaur wrote: post #214

Good: + ~90% of individuals achieve immunity. + no significant side-effects. Not so good: - two doses needed, 3 weeks apart, immunity after one month from first dose. Slow rollout. - -80C storage and transport needed. Challenging, but doable in developed countries, but still may slow down mass rollout. Not feasible in many developing countries. I still wonder about long-term immunity. Anyone can share any insight?

Not so good: Safety data is for 2 months only

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#505

Post by _ph_ »

jakozaur wrote: post #214

Good: + ~90% of individuals achieve immunity. + no significant side-effects. Not so good: - two doses needed, 3 weeks apart, immunity after one month from first dose. Slow rollout. - -80C storage and transport needed. Challenging, but doable in developed countries, but still may slow down mass rollout. Not feasible in many developing countries. I still wonder about long-term immunity. Anyone can share any insight?

Fortunately, it isn't the only vaccine in the pipeline. Curevac, another German company located pretty close to BioNTech, is also working on a similar vaccine which can be cooled in normal fridges, so is easier to roll out. They supposedly are only a few months behind. The -80c storage should be no showstopper for all densely populated regions and these are where the vaccine is most urgently needed. Over time, there will be easier to handle alternatives or we just build more deep-freezers.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#506

Post by lki876 »

dbancajas wrote: post #438
charlesdm wrote: post #364

Earlier quoted context omitted.

This is great and all, and I'm not against vaccinations, but is this safe long term? Am I the only one here who doesn't want to get inoculated in basically the first batch?

Risk of COVID19 long term effects is far worse than mRNA side effects IMO.

The possible long term side effects of the vaccine are unknown.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#507

Post by ciceryadam »

hairytrog wrote: post #371
jakozaur wrote: post #214

Good: + ~90% of individuals achieve immunity. + no significant side-effects. Not so good: - two doses needed, 3 weeks apart, immunity after one month from first dose. Slow rollout. - -80C storage and transport needed. Challenging, but doable in developed countries, but still may slow down mass rollout. Not feasible in many developing countries. I still wonder about long-term immunity. Anyone can share any insight?

Developing countries have youth immunity. When you convolve covid hospitalization / IFR as function of age with age distribution, developing countries have no risk whatsoever from COVID. that's why Brazil and India are nearing herd immunity with basically no serious medical infrastructure saturation. Median age in Africa is 19... No fks given. Covid vaccine is just for old people/developing countries.

Coronavirus: Overwhelmed India hospitals turn Covid patients away. Hospitals in the country are struggling to cope with the number of patients they’re getting. Many are dying without getting the treatment they need. https://www.bbc.com/news/av/world-asia-india-53014213

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#510

Post by tomerico »

anovikov wrote: post #182

So, out of 43538 participants, 94 got sick in both groups (who got vaccine and who got placebo) together, and this translates to "at least" 90% immunity, with 95% confidence interval. Who remembers statistics well enough to reverse the calculation and find out how many people got sick in both groups? There is a definite integer answer here.

Assuming 50% split between placebo and vaccine group, it's a 9:1 ratio - so 85 : 9 for Placebo : Vaccine COVID case.
Post reply on HN