Well, my money is on this (concept if not implementation) being the future of client-side development. Absent horrific performance/robustness problems, which seem pretty unlikely from this team, this is sounding like the droids we were looking for, the holy grail ring to unite us all, web and native. And did even Steve Yegge ever see this next big language coming?
The real power of React isn't just the virtual DOM -- it's being able to leverage Flux and an immutable, single-source-of-truth app state. Pretty much every time I turn around to build something, this combination has made what used to be an exercise in hair-pulling into an absolute joy.