51–60 of 128 posts
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Did you try those zero-sugar candy bars (often labeled as protein bars)? They work quite well for me, no messing with GLP-1 necessary.
Which do you like? Barebells salty peanut and chocolate dough over here. Though the sugar alcohols certainly aren’t great for you either, I think they were recently linked to stroke risk
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That isn’t what this says at all.
(off-topic, but since the thread already is..) HN felt like one of the last places on the internet I could have good-faith conversations with intelligent people who would form thoughtful, on-topic replies. And now it feels like the user base here has shifted enough that the voting system no longer consistently elevates the interesting comments, but the comments that reinforce people's worldviews.
Any time a user gives me a flash of annoyance with a nonsensical comment that’s the last time I see them. This isn’t a native feature but Claude will implement it for you in a really short amount of time. If you want a feature set to copy or a list of users to seed, you can just copy mine (in profile).
Kind of a useless analysis if it doesn't compare the risk after stopping GLP-1s to the risk of NEVER taking GLP-1s in the first place. We probably don't know the numbers yet, but one can easily envision a scenario like: risk of CE without GLP-1 weight loss: 20%. Risk after taking GLP-1s for 2 years: 10%. Risk after stopping GLP-1s: 12%. "Your heart attack chance goes up 20% after stopping GLP-1s!!!"
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(off-topic, but since the thread already is..) HN felt like one of the last places on the internet I could have good-faith conversations with intelligent people who would form thoughtful, on-topic replies. And now it feels like the user base here has shifted enough that the voting system no longer consistently elevates the interesting comments, but the comments that reinforce people's worldviews.
Everyone feels Eternal September sooner or later. I recommend blocking users on this site. Having hit about 800 or so blocks I find that the conversation quality has skyrocketed. You still get one or two low quality users on a thread like this (I hadn’t blocked this guy) but the truth is that it’s usually a few people. Any time a user gives me a flash of annoyance with a nonsensical comment that’s the last time I see…
I started to write a comment about having some (additional) ideas for a Chrome extension, clicked your profile, watched the YouTube video. Fantastic. I think it already does everything I wanted.
Thank you for making and open sourcing this!
Kind of a useless analysis if it doesn't compare the risk after stopping GLP-1s to the risk of NEVER taking GLP-1s in the first place. We probably don't know the numbers yet, but one can easily envision a scenario like: risk of CE without GLP-1 weight loss: 20%. Risk after taking GLP-1s for 2 years: 10%. Risk after stopping GLP-1s: 12%. "Your heart attack chance goes up 20% after stopping GLP-1s!!!"
Especially since every GLP-1 study shows almost complete regain to original weight after stopping. It’s like stopping a blood pressure medicine and then being surprised that people have more heart attacks afterwards.
Which makes sense since we have strong evidence for the GLP-1s providing significant protective benefit even without weight loss.
I’m always kind of envious of the people who were able to lose weight on GLP-1 drugs. I lost a bunch of weight a few years ago, and still need to lose a lot more (430 lb -> 330, goal 240), but I fell out of the good habits for, well, no good reasons… Decided to try Ozempic and was on it for about 6 months. Didn’t do a single thing for my appetite unfortunately, even on the max dose. Sample size of one here, but if yo…
Wegovy/Ozempic didn’t do anything for me for months. Then my doc put me on Tirzepatide+Phentermine combo and I forgot what being hungry even feels like.
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Everything is discipline. If you just always do the thing you’re supposed to you will win at life. People can’t always do the thing they’re supposed to so they supplement with drugs that help them do it: caffeine, amphetamine, SSRIs, GLP-1RAs and related drugs. In fact, everything is discipline. If you were disciplined enough to always put the basketball in the net from anywhere on the court you’d be Steph Curry. The…
Some things require talent like your examples, weight loss does not imho. The disparities in obesity and culture within country says it all.
Or do you think that somehow genetics don't play one of the largest roles in your ability to be disciplined when it comes to food?
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Some things require talent like your examples, weight loss does not imho. The disparities in obesity and culture within country says it all.
The ability to be disciplined about eating is also a talent. Or do you think that somehow genetics don't play one of the largest roles in your ability to be disciplined when it comes to food?
Also look at obesity rates across time within the same country. It’s clearly not an issue of discipline, it’s an issue of what’s being eaten.
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It doesn't reduce heart attack and stroke. It reduces appetite, kind of, and gives you a sore stomach while making you shit yourself inside out. All this can, with care, help contribute to weight loss. Weight loss can reduce heart attack and stroke, but GLP-1 does not. You could also reduce heart attack and stroke risks by not eating crap and going for a walk every so often.
What is it about GLP1s that bring out the kooks who suddenly think diet and exercise are the only valid medical treatment? Is it a moral issue?
I’m always kind of envious of the people who were able to lose weight on GLP-1 drugs. I lost a bunch of weight a few years ago, and still need to lose a lot more (430 lb -> 330, goal 240), but I fell out of the good habits for, well, no good reasons… Decided to try Ozempic and was on it for about 6 months. Didn’t do a single thing for my appetite unfortunately, even on the max dose. Sample size of one here, but if yo…
Wegovy/Ozempic didn’t do anything for me for months. Then my doc put me on Tirzepatide+Phentermine combo and I forgot what being hungry even feels like.