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'Gwada negative': French scientists find new blood type in woman

lemonde.fr

51–60 of 76 posts

Re: 'Gwada negative': French scientists find new blood type in woman

#51
post #39
post #2

The OP is low on details. There is more in this article (in french): https://www.lindependant.fr/2025/06/21/il-ny-a-quelle-qui-es... Apparently the ISBT have added this to their list: https://www.isbtweb.org/isbt-working-parties/rcibgt.html (the page still says 47 but the data tables have it added)

@dang should change the OP, entrevue is really a poor website (think tmz)

You'll need to email the mods.

Re: 'Gwada negative': French scientists find new blood type in woman

#52
post #39
post #2

The OP is low on details. There is more in this article (in french): https://www.lindependant.fr/2025/06/21/il-ny-a-quelle-qui-es... Apparently the ISBT have added this to their list: https://www.isbtweb.org/isbt-working-parties/rcibgt.html (the page still says 47 but the data tables have it added)

@dang should change the OP, entrevue is really a poor website (think tmz)

FYI, the only English article at the time of posting was Entrevue's, which is why it was initially chosen. But indeed, Le Monde's article is much better.

Re: 'Gwada negative': French scientists find new blood type in woman

#54
It’s cool to see these discoveries, but as a patient. It’s probably a nightmare to be unique in this aspect.

If American, think higher costs of care. If involved in car accident or other traumatic injury outside of normal area, good luck getting your blood transfused. Might get lucky with substitute. Surgery preparation also more complicated.

Maybe you have competent medical staff that recognize it. Maybe a few hematologists in the world familiar with your blood and history. Maybe a few neurons fire off in the back of an aging emergency physician that recalls this in a case study he/she read about in medical school/residency.

Re: 'Gwada negative': French scientists find new blood type in woman

#55
post #36
post #34

My clearly incorrect understanding was that there are ~8 blood types. So reading that there are 48 is shocking.

There are 48 blood type systems , of which ABO (giving A, B, AB, and O) and Rh (+/-) can be combined to form the 8 common types. There are effectively millions of types because all the systems combined combinatorially, but most antigens beyond ABO and Rh don't cause that much of an issue, so in emergency cases, they just go with them.

Is that what’s going on with organ matching?

Re: 'Gwada negative': French scientists find new blood type in woman

#57
post #28

Earlier quoted context omitted.

Religions compete by "virality", like viruses they evolve towards encouraging reproduction. Even if you measure "better" as "more viral" - it's not "gods" who are better - it's cultural memes (for example there's 1000 versions of christianity believing in the same gods with vastly different cultures and virality outcomes).

I'd guess there is a significant language barrier, for lack of better words, on the meaning of 'god' and 'virtue'(which might have been more descriptive, but I'm not willing to edit my comment for the clarity that it lacks out of respect for the other posters/readers) Its true that many things co-evolved with us, like viruses and blood types(yes, we're somewhat on topic again) and even though we share many similar ch…

> I know that HN is not very appreciative of religion or god.

> I'd just like to change someones perspective on that as we've all evolved from very humble beginnings, both in our personal lives and as the silly monkeys we all still sometimes are

I am not sure what the relation is between these sentences.

Re: 'Gwada negative': French scientists find new blood type in woman

#58
post #3
post #2

The OP is low on details. There is more in this article (in french): https://www.lindependant.fr/2025/06/21/il-ny-a-quelle-qui-es... Apparently the ISBT have added this to their list: https://www.isbtweb.org/isbt-working-parties/rcibgt.html (the page still says 47 but the data tables have it added)

Neither article talks about whether this is a minor or a major antigen. Blood for transfusion needs to be crossmatched against antigen types of the recipient. Many patients will tolerate several transfusions of a minor mismatched antigen before developing a sensitivity. Major antigens are what cause significant reactions that can be life-threatening. Minor antigens come into play when crossmatching for infants and pr…

Type O Negative here, they all kill me so luckily I don't have to guess!

Re: 'Gwada negative': French scientists find new blood type in woman

#59

> The discovery of new blood types isn't limited to transfusion emergencies. It also sheds light on certain previously unexplained pathologies. The specialist discusses the recent case of three siblings who had suffered from mysterious rheumatological disorders since adolescence. It was only after identifying their rare blood type that doctors were able to establish a probable link with their symptoms. How does that…

I read it to mean that the rheumatological symptoms they had were the result of their unusual blood type. Hard to say without more info, but something about that particular blood type could be linked to an inflammatory disorder.

Re: 'Gwada negative': French scientists find new blood type in woman

#60
post #3

Earlier quoted context omitted.

Neither article talks about whether this is a minor or a major antigen. Blood for transfusion needs to be crossmatched against antigen types of the recipient. Many patients will tolerate several transfusions of a minor mismatched antigen before developing a sensitivity. Major antigens are what cause significant reactions that can be life-threatening. Minor antigens come into play when crossmatching for infants and pr…

> Minor antigens come into play when crossmatching for infants I’m reminded of that American high schooler in Uganda running an orphanage and ran into this exact issue when doing a transfusion on a malnourished infant. [1] She was skilled enough to perform a transfusion and knowledgeable enough to test for a ABO+/- match but not so knowledgeable as to be sensitive to this issue with disastrous results. On the other h…

I don't know anything about the case in Uganda, but transfusion reactions can happen to anyone, even in the United States.

We don't actually express antibodies to antigens until we're exposed to them, so crossmatching won't detect a minor antigen mismatch until the first transfusion containing the antigen is administered.

That first time causes a delayed hemolytic transfusion reaction, which is generally milder than the kind of reaction crossmatching will prevent, but can be serious or even fatal.

https://en.wikipedia.org/wiki/Delayed_hemolytic_transfusion_...

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