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High vitamin B6 doses over a long period could cause irreversible nerve damage

abc.net.au

51–60 of 66 posts

Re: High vitamin B6 doses over a long period could cause irreversible nerve damage

#51
post #40
post #31

Earlier quoted context omitted.

For good reason. ZMA is taken for exercise and B6 is depleted by exercise.

So if you take these pills how do you check if you are in the safe zone, away from nerve damage?

You don't. Such is life.

Re: High vitamin B6 doses over a long period could cause irreversible nerve damage

#52

The title mentions high doses and long periods, but let’s quantify it more accurately: Cases of toxicity have been reported at doses as low as 21 mg per day, the recommended daily intake is 1.3 to 2 mg. The person in question was diagnosed with issues possibly caused by this after 2 years. Edit: Clarification, the 21 mg figure isn’t from this article but from a related document released by Australian Therapeutic Good…

> Cases of toxicity have been reported at doses as low as 21 mg per day, the recommended daily intake is 1.3 to 2 mg. The person in question was diagnosed with issues possibly caused by this after 2 years. That's very hard to believe. In my "normal" vitamin B-Complex supplement there is 20mg of B6 in the daily dose. If 21mg per day would cause nerve damage, that we'd know (and it would be an epidemic).

If the situation was that everyone in the world could take 20 mg per day without problems, but then 21 mg per day would reliably cause irreversible damage, then yes as a society we would be very clear by now on the dangers of taking too much B6.

The actual situation is probably that most people can take 2 or 3 times 20 mg per day (and some people can take 10 times 20) without problems. There is a lot of variance in the gut absorption and the rate of metabolism of a lot of micronutrients in the human body.

Re: High vitamin B6 doses over a long period could cause irreversible nerve damage

#53
post #13

Happened to me too. I had been consuming two energy drinks per day for a week or so and then my SO (who's addicted to vitamin supplements) gave me some multivitamins that I took just to be nice. Apparently that pushed me over the edge. After one night and day of sweating profusely and feeling really bad, and me thinking I've cached a bug on my daily public commute, I didn't think about it any more, until days later w…

That's so bizarre, do you take other medications, or have an usual diet?

I drink a zero-calorie energy drink every morning for the past 10 years and I've never had any issues.

Re: High vitamin B6 doses over a long period could cause irreversible nerve damage

#54

Can you get your blood tested for vitamin, mineral, enzyme levels? You don't have to do it very often. I was borderline low on D and B12, but everything else was normal. So I take B12 and only take D in the winter. I would never take a general vitamin. There's some people on the internet that advocate taking massive doses of D. But the side effects (short term and long term) are just as nasty as having a deficiency.…

I take 20,000iu of Vitamin D a day (10,000iu morning/night).

You can take quite an amount of Vitamin D safely, an example: "Results of daily oral dosing with up to 60,000iu of vitamin D3 for 2 to 6 years in 3 adult males"

https://pubmed.ncbi.nlm.nih.gov/28012936/

Re: High vitamin B6 doses over a long period could cause irreversible nerve damage

#55
post #51
post #40

Earlier quoted context omitted.

So if you take these pills how do you check if you are in the safe zone, away from nerve damage?

You don't. Such is life.

I mean, you could take a blood sample and send it to a lab, at least once? But I'm curious what the easiest way would be.

Re: High vitamin B6 doses over a long period could cause irreversible nerve damage

#57
post #55
post #51

Earlier quoted context omitted.

You don't. Such is life.

I mean, you could take a blood sample and send it to a lab, at least once? But I'm curious what the easiest way would be.

My life improved immensely after B6 supplementation, never once has a blood test shown I am deficient.
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