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It took my savings and 14 years but I’m about to beat arthritis

thetimes.com

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Re: It took my savings and 14 years but I’m about to beat arthritis

#51

Post by bittercynic »

deamanto wrote: post #49
brianleb wrote: post #20

My only commentary would be that these results do not read like clinical success, but rather something suggesting they should move on to phase III clinical trials. This is the only publication I found in a quick search: https://pubmed.ncbi.nlm.nih.gov/37976118/ >> Abstract Objectives: Nerve growth factor β (β-NGF) is a protein which is important to the development of neurons particularly those involved in the transmi…

Interesting - this looks like Beransa[1] (Librela) which is a monthly injection for canines that have osteoarthritis. My dog did not have any noticeable changes to pain after using this for 2 months so I've decided to take him off of it. [1] - https://en.wikipedia.org/wiki/Bedinvetmab

I thought the same.

My dog's been on it since last October, and it's made a big difference for him. Sorry to hear that it didn't help yours.

I've been wondering how long it would be before something similar was available for humans.

Re: It took my savings and 14 years but I’m about to beat arthritis

#52

Post by DoingIsLearning »

> The drug is based on a molecule he discovered while working at Pfizer.

Is Pharma different than Engineering in terms of IP?

If my former employer has evidence that what I am working on in a new gig was discovered while on company time using company resources couldn't they sue?

Re: It took my savings and 14 years but I’m about to beat arthritis

#53

Post by armini »

DoingIsLearning wrote: post #52

> The drug is based on a molecule he discovered while working at Pfizer. Is Pharma different than Engineering in terms of IP? If my former employer has evidence that what I am working on in a new gig was discovered while on company time using company resources couldn't they sue?

It says he used the money from redundancy to continue with his work. Pfizer would have a hard time winning that case because the discovery was made past their employment. Having field knowledge doesn't make it a crime. Coding is different because it's easier to copy paste functions & classes, it also doesn't help that everything has timestamps. Your best bet is to rewrite everything.

Re: It took my savings and 14 years but I’m about to beat arthritis

#54

Post by DoingIsLearning »

armini wrote: post #53
DoingIsLearning wrote: post #52

> The drug is based on a molecule he discovered while working at Pfizer. Is Pharma different than Engineering in terms of IP? If my former employer has evidence that what I am working on in a new gig was discovered while on company time using company resources couldn't they sue?

It says he used the money from redundancy to continue with his work. Pfizer would have a hard time winning that case because the discovery was made past their employment. Having field knowledge doesn't make it a crime. Coding is different because it's easier to copy paste functions & classes, it also doesn't help that everything has timestamps. Your best bet is to rewrite everything.

Maybe it's semantics, but I understand it was discovered while at Pfizer and further developed post-redundancy. IANAL but it definitely feels like a grey area?

Re: It took my savings and 14 years but I’m about to beat arthritis

#55

Post by robbiep »

skybrian wrote: post #36
ghostly_s wrote: post #24

Earlier quoted context omitted.

but the sentence prior says "it restores protective processes to diseased joints and enables the regeneration of affected tissues." I don't understand how it does if it's just blocking pain signals.

I don’t know about this case, but in general, the body’s reaction to pain sometimes makes things worse, so relieving pain can be part of encouraging recovery.

Degenerative diseases don’t de-pathologise when you remove their pain

Re: It took my savings and 14 years but I’m about to beat arthritis

#56

Post by encomiast »

DoingIsLearning wrote: post #52

> The drug is based on a molecule he discovered while working at Pfizer. Is Pharma different than Engineering in terms of IP? If my former employer has evidence that what I am working on in a new gig was discovered while on company time using company resources couldn't they sue?

Doesn’t the article touch on this:

> On leaving the company, he acquired the intellectual property [IP] rights from his former employer…

Re: It took my savings and 14 years but I’m about to beat arthritis

#57

Post by Vecr »

sargun wrote: post #48
fnord77 wrote: post #17

They had very good, robust Phase II results. Thinks can go wrong in Phase III. Relyvrio (HIV vaccine) did well in P2 but flopped on P3. Cancer drug xevinapant failed in P3 after Merck executives were reassuring analysts that the failure of a phase 3 trial of xevinapant was “unlikely.”

Relyvrio was ALS drug. I don't think any HIV vaccines have gotten to phase III yet.

I don't know if the trials were technically phase 3, but the 2008 Canarypox attempt was pretty big and failed.

Re: It took my savings and 14 years but I’m about to beat arthritis

#58

Post by ruok_throwaway »

One thing I learned repeatedly while dealing with a chronic health condition is to never assume that you're "about to beat it". I've had that feeling about 1000 times now, and telling that to my family and friends just made me sound like an idiot, since I would invariably regress again.

Now I'm at a point I would only be fine with saying this if I didn't have any issues after a prolonged interval.

Re: It took my savings and 14 years but I’m about to beat arthritis

#60

Post by breck »

DanHulton wrote: post #15
breck wrote: post #12

[flagged]

Strong disagreement, and I think if you'd spoken with any serious arthritis sufferers who are desperate for literally anything, you'd realize how incorrect you are.

> if you'd spoken with any serious arthritis sufferers

Why do you assume I haven't?

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