Here’s one of the fundamental problems with studying human diet and psychology, from the article: > The best way to assess the effects of alcohol would be to randomly assign people to drink it or not in childhood and then monitor their health and drinking over the rest of their lives. Since such studies cannot be done, researchers instead have to ask people about their drinking habits and follow them over much shorte…
I hope someday we could develop computers that can do a molecularly accurate simulation of the human body. Then we could try all the inputs we can imagine, with a bunch of different sets of genes, and figure out exactly what's good or not.
Why many studies wrongly claim it's healthy to drink a little alcohol
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Re: Why many studies wrongly claim it's healthy to drink a little alcohol
#52Here’s one of the fundamental problems with studying human diet and psychology, from the article: > The best way to assess the effects of alcohol would be to randomly assign people to drink it or not in childhood and then monitor their health and drinking over the rest of their lives. Since such studies cannot be done, researchers instead have to ask people about their drinking habits and follow them over much shorte…
Re: Why many studies wrongly claim it's healthy to drink a little alcohol
#53Re: Why many studies wrongly claim it's healthy to drink a little alcohol
#54Society wise, alcohol is the the direct cause, or a major factor in heart disease, cancer, suicide, gun deaths, car deaths and injuries, etc.
Re: Why many studies wrongly claim it's healthy to drink a little alcohol
#55Earlier quoted context omitted.
Yes, but those populations are far from completely dry. They may drink less, but do not represent a scientific control group. If you did find a totally dry community, the other cultural differances may well muddy the results too (diet, relationship to medical care etc).
Do you have support for that claim? Large, large parts of the Islamic world are not westernized at all — I would be very surprised if rural Yemeni housewives or Socotran shepherds ever drink, or for that matter 99% of people in pre-tourist-visa Saudi. Hard agree on their being a myriad of confounding factors from genetics over climate and family relationships to diet, though...
Re: Why many studies wrongly claim it's healthy to drink a little alcohol
#56Ethanol is metabolized to acetaldehyde. Aldehydes form crosslinks between proteins and DNA (and DNA with itself). Inactivation of the aldehyde-metabolizing ALDH2 enzyme (which happens in 50% of East Asians) increases risk for various disorders including cancer and late-onset Alzheimer's. Cancers linked to alcohol use: https://www.cancer.org/cancer/risk-prevention/diet-physical-... The American Cancer Society recommen…
Acetaldehyde is also be metabolized by the brain for energy. May be why some people get so addicted.
One stereotype I’ve heard is that people quit drinking and then become addicted to coffee. Coffee apparently can have acetaldehyde in it.
Re: Why many studies wrongly claim it's healthy to drink a little alcohol
#57Earlier quoted context omitted.
It clearly seems beneficial and/or enjoyable for some (not me so much), and tobacco and opiates seem like they do their fair share of damage as well.
Tobacco is estimated to cause more deaths, at least globally: https://ourworldindata.org/grapher/substances-risk-factor-vs...
Re: Why many studies wrongly claim it's healthy to drink a little alcohol
#58Re: Why many studies wrongly claim it's healthy to drink a little alcohol
#59Have there been studies of nominally non-drinking sub-populations, such as Mormons or Muslims, to understand the effects of alcohol?
I imagine picking people from one particular religion or culture is bound to introduce statistical skews. Mormons do seem to skew toward abstinence from a lot of unhealthy habits, but the stereotype is that they drink a lot of soda, right? That’s bound to do something. Plus if a group has a strong stigma against alcohol you’ll probably get some members with an unusually high incentive to miss-report whether or not th…
As a former member of such a group, this is exactly right. Even if it's completely anonymous, there's a strong and absurd sense of "God is watching me fill out this form, better make myself look good".
Re: Why many studies wrongly claim it's healthy to drink a little alcohol
#60This NS piece is complete misinformation. This below is by a writer who has been writing about this sort of thing for years. "Tim Stockwell has been up to his old tricks. In a study that was widely publicised this week despite being published in January, he claims - yet again - that moderate drinking does not confer health benefits. The study is largely a rehash of his meta-analysis from last year (which I wrote abou…
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