In terms of installations, sure. In terms of total data, probably not. In terms of important data, 100% not. Important data needs guarantees, and its privacy is second to its longevity. Server side and centralized beats client side decentralized for all but sensitive consumer data.
You may be shocked to learn how much of the world's "important data" lives in Excel files.
Easier to copy/replicate, packaged with a GUI, provider with a commercial relationship, programmatic support ( formulas, vba, COM, raw data access)
Would be closer to sqlite than server side though, but it's capacity for replication and sharing makes it more adecuate for sqlite.
Sqlite's lack of GUI gives data a programmer bias, important data uses excel because unless you are in a technocratic environment.