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FDA approves first medication to reduce allergic reactions to multiple foods

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Re: FDA approves first medication to reduce allergic reactions to multiple foods

#51

Post by moneywoes »

yosito wrote: post #42
DoreenMichele wrote: post #35

It's a 16 to 20 week course of treatment and reduces risk of anaphylaxis for accidental exposure to food allergens. There is at least one other drug that is used to treat peanut allergies, but this treats multiple food allergies. Given that anaphylaxis can be deadly and staff at food places can be sometimes less than reliable about food allergy concerns, I can see this being appealing to someone with severe food alle…

> staff at food places can be sometimes less than reliable about food allergy concerns As someone with Celiac disease, who often eats at restaurants, this is a bit of an understatement. Even in restaurants where things are marked allergen free on the menu, it is often the case that staff will make mistakes. More often than not, staff aren't even informed about the basics of food, things like eggs and dairy being two…

hi fellow celiac

any upcoming new celiac tech you find exciting?

Re: FDA approves first medication to reduce allergic reactions to multiple foods

#53

Post by joshmarinacci »

There’s something I don’t understand. I took allergy shots to treat my sinus allergies to grass pollen, pet dander, and rag weed. It’s not perfect but it built up my tolerance to these so that I can have cats and survive grass season. Why can’t a similar treatment work for food allergies.

Re: FDA approves first medication to reduce allergic reactions to multiple foods

#54

Post by oaiey »

monero-xmr wrote: post #18
gnicholas wrote: post #7

From what I read of this, it's very expensive (thousands/mo), requires at least monthly injections at a facility, has a risk of anaphylaxis (so the injections can't be done at home), doesn't eliminate the risk of allergic reactions, and has no off-ramp (so you have to take it forever). Not exactly a silver bullet... My first thought was that it could be good for kids, who are less good at checking for trace amounts o…

It’s annoying to read “so and so new drug costs too much.” Creating new drugs is absurdly expensive. Most new drugs target small population groups, which is why treatments do not already exist - the low hanging fruit with large market potential gets targeted first. Just be happy a flag is planted in the ground. New drugs will be created from this that are different enough to avoid the patent, and new research will en…

While true, there is more money going in executive compensation / stock than into research.

So there is plenty of space for lower prices. Plenty.

Re: FDA approves first medication to reduce allergic reactions to multiple foods

#55

Post by feverzsj »

dukeofdoom wrote: post #17

[flagged]

Immune system needs to take in some dirty stuffs to adjust itself. The hygiene standards and ultra-processed foods in developed countries have made people's immune system highly sensitive by not giving them chance to be better adapted.

Re: FDA approves first medication to reduce allergic reactions to multiple foods

#56

Post by mbrubeck »

joshmarinacci wrote: post #53

There’s something I don’t understand. I took allergy shots to treat my sinus allergies to grass pollen, pet dander, and rag weed. It’s not perfect but it built up my tolerance to these so that I can have cats and survive grass season. Why can’t a similar treatment work for food allergies.

There is a treatment called Palforzia for peanut allergy that works similarly.

Re: FDA approves first medication to reduce allergic reactions to multiple foods

#58

Post by scheme271 »

kortex wrote: post #40
dukeofdoom wrote: post #17

[flagged]

A) hygiene hypothesis, people ate way more dirt and straight up almost everyone had worms B) the people with really bad food allergies like Coeliac just died young. We have severe amnesia when it comes to just how rough the state of health was until basically the 50s (eradicating Polio is a big turning point). Fortunately, we can learn about history so we don't repeat it :massive eyeroll:

There's a lot of evidence indicating that the hygiene hypothesis is not accurate or at the very least not the whole story. The old friends hypothesis suggests that exposure to certain pathogens is just as important or more so. Also microbiomes may play a part in things as well. Everything is a bit up in the air, tbh.

Re: FDA approves first medication to reduce allergic reactions to multiple foods

#59

Post by error_logic »

dboreham wrote: post #26
dukeofdoom wrote: post #17

[flagged]

The FDA didn't remove dirt from kids' environment.

They also didn't prevent the abundance of pesticides and herbicides which may cause immune responses to other things in food.

Then there's all the microplastic and teflon and whatever else seeps into the food supply from industrial equipment operation.

We've not only eliminated a lot of "dirt" but introduced a lot of things which can cause issues whether due to volatility or chemical stability causing inability of the body to clear it up.

Re: FDA approves first medication to reduce allergic reactions to multiple foods

#60

Post by looping8 »

modeless wrote: post #46
DoreenMichele wrote: post #35

It's a 16 to 20 week course of treatment and reduces risk of anaphylaxis for accidental exposure to food allergens. There is at least one other drug that is used to treat peanut allergies, but this treats multiple food allergies. Given that anaphylaxis can be deadly and staff at food places can be sometimes less than reliable about food allergy concerns, I can see this being appealing to someone with severe food alle…

The study lasted 20 weeks, but I believe you have to continue the treatment indefinitely if you want the effects to continue. It's not a permanent fix, and a once or twice monthly injection for the rest of my life is not something I'd like to sign up for.

We can hope it's not for the rest of one's life but only until a better solution is found. For people with deadly allergies, a few years of injections might not be too big of a price, I think.
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