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Case study: Rapid recovery from autism after treatment of aspergillus (2020)

pubmed.ncbi.nlm.nih.gov

51–60 of 69 posts

Re: Case study: Rapid recovery from autism after treatment of aspergillus (2020)

#51
post #7

Come on people, one case? Was he really properly diagnosed of ASD? How did this get so front page up after all covid and colloidal silver, MMS or hydroxychloroquine

[flagged]

We are witnessing a new step in human evolution to the Homo Dunningkrugerensis

Re: Case study: Rapid recovery from autism after treatment of aspergillus (2020)

#52
post #30

Autism diagnosis are based on nothing more than behavior. The facts here are that one child behaved in a manner consistent (enough) with the criteria for ASD. After treating a fungal infection, the child’s behavior changed. I think it’s a stretch to associate fungal infections with autism. There are probably many ailments that could trigger typical ASD behaviors.

> I think it’s a stretch to associate fungal infections with autism.

I think this tends to discount the emerging narratives about the link between gut microbiome and neurotransmitters.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504309/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234057/

https://www.frontiersin.org/articles/10.3389/fcell.2021.6491...

https://www.theatlantic.com/health/archive/2015/06/gut-bacte...

People are not used to this idea that what happens in your microfauna may play this super important role in what happens in your head, but there are already links to things like parkinsons and anxiety/depression.

To me it's not a stretch to associate fungal infections with a neurological disorder or symptom presentation at all, it's a pretty natural extension of the research that's happened over the last 10-15 years. And in several (human) case studies and research scenarios (mice), there is evidence for an actual causal link and not just "people with neurodivergence have fucked up microbiomes" too - treat the microbiome and you treat the parkinsons, or the ASD, and you can induce autism-like symptoms in mice by infecting their microbiome with B. fragilis.

Not a doctor but this does seem like probably the biggest thing people have tended to ignore (studiously, in some cases), that microbiome might play this huge role in things like weight or mental health. 100 years later, we are going to look back at this as an obvious case of science more or less ignoring what was right in front of our faces because it wasn't medicalized yet.

Re: Case study: Rapid recovery from autism after treatment of aspergillus (2020)

#54

Lol https://en.m.wikipedia.org/wiki/William_Shaw_(laboratory_own... Leave it to HN to fall for grifters, but then again I suppose this must just probably just a massive conspiracy by the big bad Illuminati or something to profit off mainstream understanding of autism and we should trust the “science” this time. (To be fair, I can’t find anything that points to the main author being nearly on the same level of quacker…

Can you please make your substantive points without snark or (to use the wording from https://news.ycombinator.com/newsguidelines.html) sneering at the community?

It's human nature to make ourselves feel superior by putting down others, but it skews discussion in a way that goes against what we're trying to optimize for here (https://hn.algolia.com/?dateRange=all&page=0&prefix=true&sor...).

Edit: it looks like you've unfortunately been breaking the site guidelines in a lot of what you've been posting here. Can you please review them and stick to them? I don't want to ban you but we end up not having much choice if an account keeps posting in this low-quality way.

Re: Case study: Rapid recovery from autism after treatment of aspergillus (2020)

#55

Lol https://en.m.wikipedia.org/wiki/William_Shaw_(laboratory_own... Leave it to HN to fall for grifters, but then again I suppose this must just probably just a massive conspiracy by the big bad Illuminati or something to profit off mainstream understanding of autism and we should trust the “science” this time. (To be fair, I can’t find anything that points to the main author being nearly on the same level of quacker…

This is the second terrible autism fake science article on the front page today after https://news.ycombinator.com/item?id=37716167

Re: Case study: Rapid recovery from autism after treatment of aspergillus (2020)

#56
Might be a quack, but I would not put it past the idea that fungi can act in different ways within our bodies, especially if our immune system is weak where it might be more opportunistic rather than non harmful for healthy immune systems.

Paul Offit also has a great book on the other topic of what to look out for when it comes to quackery called "Do You Believe in Magic?" where he talks about Jenny McCarthy and various doctors who tried to support that movement.

Re: Case study: Rapid recovery from autism after treatment of aspergillus (2020)

#57

If you’re inclined to take this paper seriously, or if you feel like reading a very badly produced article, I recommend reading the full paper. It’s just a few pages, and a light read. Also, you’ll get to ponder how in the “List of abnormal clinical symptoms of the child with an autism spectrum disorder prior to antifungal therapy”, the first entry is “Silly”. No standardized assessments of autism (e.g. the ADOS) are…

I honestly thought you were joking or at least over exaggerating. You aren’t, haha.

Some others from that list:

- Curious/into things

- Likes fans

- Farting (stinky)

- Looks sick

Amazing criteria.

Re: Case study: Rapid recovery from autism after treatment of aspergillus (2020)

#58

Earlier quoted context omitted.

Autism spectrum disorder isn’t a disease like COVID with a known cause. There are likely many things that lead to symptoms consistent with ASD. According to the link the mold infection has biomarkers, and presumably it’s possible that some people who have this infection and ASD can be treated for the infection and might see improvement. However I don’t think the article implies in any way that ASD is caused by mold i…

When my son was diagnosed with autism a quarter century or so ago, we would see claims like this popping up now and again. At first we would get excited, but over time we learned to ignore them. Desperate parents make easy targets for grifters and quacks so you have to expect this kind of thing. The worst part is when well-meaning family and friends keep excitedly sending you articles or giving advising you on these…

My special needs brother predates autism. I was always annoyed with the question 'what's wrong with your brother' as if slapping a label on him would fix things. And big picture there isn't anything wrong with him other than a few deep deficits which no ones going to be able to undo.

My brother has a few friends with similar deficits, just different ones. That makes me dubious of the idea of autism as a particular 'disease'. In fact I find the disease model insulting.

Re: Case study: Rapid recovery from autism after treatment of aspergillus (2020)

#59
post #2

The paper is dated August 2020. Does anyone know a follow up study done?

The child and/or his mother would have been in each newspaper and late night shows at this time telling everybody his history. As that didn't happened in three years, the recovery seems either temporary or fake, unfortunately

Re: Case study: Rapid recovery from autism after treatment of aspergillus (2020)

#60

If you’re inclined to take this paper seriously, or if you feel like reading a very badly produced article, I recommend reading the full paper. It’s just a few pages, and a light read. Also, you’ll get to ponder how in the “List of abnormal clinical symptoms of the child with an autism spectrum disorder prior to antifungal therapy”, the first entry is “Silly”. No standardized assessments of autism (e.g. the ADOS) are…

I honestly thought you were joking or at least over exaggerating. You aren’t, haha. Some others from that list: - Curious/into things - Likes fans - Farting (stinky) - Looks sick Amazing criteria.

If this is for children I think we get a clinical diagnosis of 150% autism amongst the 3-5 cohort.
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