What if you spit it out? Or what about french-kissing someone, can you give this bacteria to the other person that way?
Yes I believe that would happen if it outcompetes “native” non-gmo bacteria.
Good luck selling it for 20k/dose then.
Gene-Engineered Mouth Bacteria
51–60 of 312 posts
Re: Gene-Engineered Mouth Bacteria
#52Charging $20,000 for a dose? Really?
What’s a fair price? Spending well over $20k on dental work over a lifetime is easy for many people. Adjust for inflation and it’s a steal. Cavities often lead to eventual root canals which require a crown which one day will probably require an extraction and a dental post and prosthetic tooth. That is probably around $8k or more for a single tooth at todays rates.
Re: Gene-Engineered Mouth Bacteria
#53What if you spit it out? Or what about french-kissing someone, can you give this bacteria to the other person that way?
The company that made the bacteria gets less money and any ill-effects will need active management going forward.
The key is whether the unknown active management of this bacteria is preferable to the immense expense and problems of tooth decay.
Re: Gene-Engineered Mouth Bacteria
#54Earlier quoted context omitted.
Not just EU, Switzerland too. That tells me everything I need to know, the site owner simply wants to steal my personal data and use it against me.
Surely that’s the reason and not the EU penalty for simply storing cookies “without consent” being so severe as to practically negate the value of EU citizens on the internet.
[deleted]
Re: Gene-Engineered Mouth Bacteria
#55Charging $20,000 for a dose? Really?
You can engineer something yourself using a kit like the one they give to iGEM participants. If the business model relies on exorbitant pricing, then there's something off somewhere.
Re: Gene-Engineered Mouth Bacteria
#56The question I always have with this type of stuff is: why is it not _already_ huge. Cavities were a big thing already in 1985. If this was a miracle cure in 1985 then I do not believe that this study would have ended in 'ok that was fun, back to normal life'. This has huge commercial potential if true, so the apparently implications is that there is something blocking that commercial application.
Was it FDA? Was it side effectives? Is it impossible to scale this up? What is it that made this "miracle cure" just stop.
Re: Gene-Engineered Mouth Bacteria
#57[deleted]
Re: Gene-Engineered Mouth Bacteria
#58Doing a couple Google/Twitter searches for this company it's pretty obvious it's coming out of the Berkeley-area EA/rationalist cluster, which automatically makes me pretty skeptical. These people don't exactly have a stellar track record of medical startups (recall all the hype around MetaMed, which delivered precisely nothing).
Longevity biotech came from a similar milieu and has been doing very well: https://english.elpais.com/economy-and-business/2023-07-17/t...
(along with AI companies of course)
Re: Gene-Engineered Mouth Bacteria
#59This is certainly an interesting idea, but there's absolutely no way for anyone to judge whether the claim on this page is bulletproof true, something plausible worth researching more, or just total nonsense. But the fact that there isn't a single link to any scientific paper or evidence whatsoever, or even a single person's name linked to the site (or source of funding or anything ), makes me assume this is just spa…
Yeah, if it's in "patent hell and FDA hell" there should be applications and evidence of that online, right?
Re: Gene-Engineered Mouth Bacteria
#60It's easy enough to test this without investor money, you just need a simple kit and some dentures (not literally, I meant teeth essentially). The design of the experimental protocol is key.