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Cannabis use disorder and subsequent risk of depression and bipolar disorder

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Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#51

Post by andrewstuart »

daft_pink wrote: post #12
andrewstuart wrote: post #5

There's lots of people who take this sort of thing as reason to criminalize cannabis. Regardless of the problems, it is still a personal health issue. Criminalizing causes more harm than good.

I don't think people should be put in jail for cannabis. However, we shouldn't be devoting our tier 1 retail space or having startups with massive advertising budgets pushing it. It should be sold as a generic drug by pharmacies that make most of their business from other drugs not dispensary entrepreneurs creating massive retail brands like alcohol.

I certainly agree with this.

In Australia, tobacco is sold behind the counter. Tobacco has plain packaging and there is no advertising or promotion.

This is the way marijuana should be sold - cheap, clean, legal, available, but behind the counter and not advertised or promoted. It should not be like California or Thailand where you can go to cafes or marijuana shops.

Marijuana should not be treated as alcohol however - advertised, commercialised and glorified. Available, cheap, clean is enough.

Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#52

Post by paulmd »

alchemist1e9 wrote: post #29
riffic wrote: post #11

Earlier quoted context omitted.

[flagged]

More like society has trouble facing the truth about one of it’s popular vices. The empirical evidence is overwhelming that there are very serious public health issues, yet so many people have an extremely biased vested interest in either continuing their vice, profiting from others, or simply getting votes. It will probably go down in 20 years as a disgraceful period of denialism, the promotion and legalization and…

Nah, people just realize that it’s not worth continuing to fight the drug war and kill and imprison hundreds of thousands just because little skylar turned into a bit of a pothead for a couple years.

This is exactly the kind of pro-drug war astroturfing GP is talking about. Think of the children, think of the health risks!

The risk has always been non-zero, but it’s not high either. And the net reduction in dead dogs and botched drug raids alone is a countervailing factor.

Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#53

Post by [deleted] »

kromem wrote: post #45

Just a reminder for anyone reading this that CBD has been shown to be an effective antipsychotic in its own right [1], and particularly in regards to THC related psychosis [2]. It's probably not a great idea that the industry is moving towards high concentration THC and low to zero CBD product. The "naturally occurring plant" is getting further and further from what's naturally occurring with the psychosis inducing c…

[deleted]

Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#54

Post by kromem »

kikokikokiko wrote: post #27

Does it really surprises anyone that a psychoactive drug have psychoactive effects on it's users? This whole "cannabis is an inofensive natural plant" is so dumb, of course a drug that alters your mind and is used regularly will produce side effects on it's users. The other thing that I always try to warn my pot head friends is about the pulmonary risks involved in cannabis use. I know guys that smoke all day pretty…

As it naturally occurs it probably was fairly innocuous in longer term psychoactive effects.

Heirloom strains had CBD alongside THC.

CBD on its own has been as effective in research as antipsychotics in treating schizophrenia, and very much mitigates the OP effects in research.

But the vast majority of product today has selectively bred out the CBD.

It's time we stop talking about cannabis use and start regarding it as THC use, as the full spectrum of the original plant is no longer what people are really using.

It'd be like selectively breeding high arsenic almonds and then people getting sick eating them and declaring the problem as one impacting almond consumption instead of more specifically arsenic consumption.

THC unmitigated by CBD is a psychiatric sleeping giant that's currently not being addressed because the pendulum swing is still glowing strong with legalization momentum and any criticism is generally dismissed as simply being anti-cannabis use generally.

Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#55

Post by avodonosov »

sandofsky wrote: post #26

I can't see the full study methodology without an account. That said… The challenge with running studies ethically is that you can't split your test groups into two groups and somehow induce cannabis use disorder and see if major depression, bipolar, etc results from it. Rather, you can see if the people who naturally develop the disorder also have those problems. The flaw in this reasoning is that people who develop…

Isn't it possible to distinguish casuality between A and B from correlation by simply considering set sizes?

    !A & B
    A & !B
    A & B
    !A & !B
    A
    B
    !A
    !B

Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#56

Post by mvdtnz »

01100011 wrote: post #22

Obviously people with mental discomfort are more likely to seek comfort in mind altering substances. That said, as someone who is bipolar, has bipolar friends and has used cannabis for a significant portion of my half-century on Earth, cannabis usage is proportional to mood instability in myself and my friends. I have taken extensive breaks and noticed I am much more mentally resilient and less emotionally labile whe…

> Obviously people with mental discomfort are more likely to seek comfort in mind altering substances.

This can be true at the same time that cannabis use disorder increases the likelihood of mental illness is true. These are not mutually exclusive.

Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#57

Post by [deleted] »

l33t7332273 wrote: post #37
sandofsky wrote: post #26

I can't see the full study methodology without an account. That said… The challenge with running studies ethically is that you can't split your test groups into two groups and somehow induce cannabis use disorder and see if major depression, bipolar, etc results from it. Rather, you can see if the people who naturally develop the disorder also have those problems. The flaw in this reasoning is that people who develop…

How is correlation vs causation determined in other studies where a control group cannot be used?

[deleted]

Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#59

Post by cratermoon »

sandofsky wrote: post #26

I can't see the full study methodology without an account. That said… The challenge with running studies ethically is that you can't split your test groups into two groups and somehow induce cannabis use disorder and see if major depression, bipolar, etc results from it. Rather, you can see if the people who naturally develop the disorder also have those problems. The flaw in this reasoning is that people who develop…

Try this: full PDF: https://static1.squarespace.com/static/5fa2eabb04edcf45a6512...

Re: Cannabis use disorder and subsequent risk of depression and bipolar disorder

#60

Post by kromem »

kromem wrote: post #45

Just a reminder for anyone reading this that CBD has been shown to be an effective antipsychotic in its own right [1], and particularly in regards to THC related psychosis [2]. It's probably not a great idea that the industry is moving towards high concentration THC and low to zero CBD product. The "naturally occurring plant" is getting further and further from what's naturally occurring with the psychosis inducing c…

Eh, can't edit in my client. First link: https://www.psychiatrictimes.com/view/understanding-relation...
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