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Widely used chemical strongly linked to Parkinson’s disease

science.org

51–60 of 344 posts

Re: Widely used chemical strongly linked to Parkinson’s disease

#51
post #3

When you drink your coffee without caffeine in your 30 for escaping a harm from caffeine, but end up with Parkinson in your 60+.

Why would you drink coffee if not for the caffeine. It's not exactly the most delicious drink.

I don't understand this - If you don't enjoy the experience of drinking coffee, and just want the caffeine, then why not just take a caffeine pill?

Re: Widely used chemical strongly linked to Parkinson’s disease

#52

Earlier quoted context omitted.

Why would you drink coffee if not for the caffeine. It's not exactly the most delicious drink.

Have you not had coffee with fresh ground beans less than 4 weeks after roast? If not get to your nearest real coffee shop pronto!

can confirm. Decent fresh beans are the key.

Re: Widely used chemical strongly linked to Parkinson’s disease

#53

"After adjusting for differences in age, sex, race, and ethnicity, the scientists found veterans from Camp Lejeune had a 70% higher rate of Parkinson’s disease than the Camp Pendleton group." Why didn't they adjust for socioeconomic status? Wealthier people tend to be able to afford better medical care, live in healthier environments, eat healthier foods, etc. These could all be confounding factors, and a study like…

They were all active duty military and largely the same socio-economic cohort, and use the same medical system. Maybe they could draw a distinction between enlisted and commissioned, but my hunch is the disparity between raw numbers would lead to low statistical power.

(This isn’t to say they originally came from the same socio-economic group, but that isn’t the type of distinction usually made in these kinds of studies.)

Re: Widely used chemical strongly linked to Parkinson’s disease

#54

> It inhibits complex 1, the leading enzyme in a chain of reactions that convert food to energy in cellular organelles called mitochondria. So they upside is that it probably significantly reduces your risk of both cancer and type 2 diabetes, which you're >100x more likely to die from than Parkinson's. There are even longevity bloggers, like Peter Attia, who advocate that everyone should be taking mitochondrial compl…

The chemical in question was originally banned due to its carcinogenic properties.

Re: Widely used chemical strongly linked to Parkinson’s disease

#56

Started gabapentin, couple weeks later I had Parkinson’s Took awhile to clear up. Had a few rounds of this before I figured out that gabapentin induced Parkinson’s was a thing. https://pubmed.ncbi.nlm.nih.gov/31633228/

Did you mean Parkinsonism, because that is an umbrella term for symptoms, not necessarily the disease. It's an important distinction, because Parkinson's is degenerative.

https://www.parkinson.org/library/fact-sheets/parkinsonism

Re: Widely used chemical strongly linked to Parkinson’s disease

#57
post #29

> It inhibits complex 1, the leading enzyme in a chain of reactions that convert food to energy in cellular organelles called mitochondria. So they upside is that it probably significantly reduces your risk of both cancer and type 2 diabetes, which you're >100x more likely to die from than Parkinson's. There are even longevity bloggers, like Peter Attia, who advocate that everyone should be taking mitochondrial compl…

Is there any evidence it actually reduces those risks, or is it speculation?

Mitochondrial disfunction is the basis for a huge number of cancers. See “Tripping over the Truth: The Metabolic Theory of Cancer”[0] for a good history of it.

[0] https://www.goodreads.com/book/show/23496164

Re: Widely used chemical strongly linked to Parkinson’s disease

#58
post #49
post #18

Earlier quoted context omitted.

What is Tricholoroethylene? "A widely used chemical" ....

Imagine this headline A widely known basketball team wins NBA finals Clickbait?

Depends on the audience i guess, im not sure i can name a basketball team.

Does the average reader of science.org know what trichloroethylene is without a prompt?

Re: Widely used chemical strongly linked to Parkinson’s disease

#59
post #49
post #18

Earlier quoted context omitted.

What is Tricholoroethylene? "A widely used chemical" ....

Imagine this headline A widely known basketball team wins NBA finals Clickbait?

Yes and a straw man also. Widely known and widely used are definitely not the same.

More people know the names of basketball teams than know the significance of TCE.

Re: Widely used chemical strongly linked to Parkinson’s disease

#60

It was heavily contaminated water that they all consumed, of the 279 veterans there were 0.33% cases vs the statistically expected 0.21%. Which means they found 9 people with Parkinson, instead of the expected 6. [edit] ignore the comment, read it wrong, its 279 cases

Different order of magnitude too: 0.33% of 279 people would be 0.92 people, not 9 people.
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