51–60 of 182 posts
Earlier quoted context omitted.
Why were doctors prescribing antibiotics for COVID?!
When I was in Peru, they kind of prescribed antibiotics for everything. Persistent cold? Antibiotics. Like that. Source: lived there with Peruvian partner for 18 months.
I am quite sure, that if a sufficient bounty was given out for developing new kinds of antimicrobials, they'd be developed in no time. The problem is that cost and risk of development and trials is too large for the current rewards, and hence there is very little new antimicrobials being developed. There are very many promising leads though, and either making development cheaper (by requiring smaller or fewer clinica…
I'm not sure. Not only do you need to kill bacteria, you need to not kill or harm humans at the same time. That is a high bar.
I am quite sure, that if a sufficient bounty was given out for developing new kinds of antimicrobials, they'd be developed in no time. The problem is that cost and risk of development and trials is too large for the current rewards, and hence there is very little new antimicrobials being developed. There are very many promising leads though, and either making development cheaper (by requiring smaller or fewer clinica…
The problem with developing a new antibiotic is that doctors from third world countries will prescribe them like candy - so the bacteria become resistant to it fast. In fact Im very scared when I read that there are plans to use antibiotics "borrowed" from ants, or bees, because probably the antibiotic will be dumped by tons and become useless after 2-3 years, while all the ants or bees in the world die out. Apart fr…
Earlier quoted context omitted.
How is this putting less selection pressure on them?
Not OP, but it's kinda like boiling or alcohol versus poisoning (which is essentially how most drugs work). Certain attack vectors are literally unevolvable, as they would require fundamentally different building blocks to be able to be able to handle, which is too big of a leap for evolution to make.
The challenge is: 1) finding something that kills mostly/only cells we don't want in or around our cells 2) kill them in such a ruthlessly efficient way that there are no survivors
As a sibling points out, the vacuum of space does #2 quite well. Actually we have a lot of stuff that handles #2 quite well. But #1, differentiating between "good" and "bad" with our murder machines, is pretty much an unsolved problem.
I bet all those antibiotics prescribed for covid didn't help as well. That was happening on a massive scale in my country
I’m still amazed at how many people are able to get their dr to prescribe them antibiotics just by asking. I knew someone who had a cold and said “but I asked my Dr for some antibiotics and I’m taking DayQuil so I’ll be better in a day or two” Im always left open mouthed gaping at them like… even if YOU don’t know. But at least the Dr should …
At the risk of sounding ignorant… I’ve been hearing stuff like this for twenty years now. And yet the crisis hasn’t happened. Why is that?
Older or sicker folks who end up in a hospital or nursing home / rehab are very vulnerable to stuff like TB or c.diff. Cdiff is huge now as hospitals purge support staff and are filthy. If you’re old or immune compromised, you’re gonna pick up a severe, hard to treat infection if you spend time in the ER or general medical area of a hospital. The “money areas” of the hospital are usually better.
Earlier quoted context omitted.
How is this putting less selection pressure on them?
Not OP, but it's kinda like boiling or alcohol versus poisoning (which is essentially how most drugs work). Certain attack vectors are literally unevolvable, as they would require fundamentally different building blocks to be able to be able to handle, which is too big of a leap for evolution to make.
Earlier quoted context omitted.
why do we need "rewards"? just have a national lab produce them
If this ends up being the approach, I really hope it will be led by a country with a few decades experience in successfully being socialist. The US really has no business doing this, the government departments and oversight boards that exist today are much too compromised by the pharmaceutical industry to pull this off.
Earlier quoted context omitted.
Why were doctors prescribing antibiotics for COVID?!
When I was in Peru, they kind of prescribed antibiotics for everything. Persistent cold? Antibiotics. Like that. Source: lived there with Peruvian partner for 18 months.
I am quite sure, that if a sufficient bounty was given out for developing new kinds of antimicrobials, they'd be developed in no time. The problem is that cost and risk of development and trials is too large for the current rewards, and hence there is very little new antimicrobials being developed. There are very many promising leads though, and either making development cheaper (by requiring smaller or fewer clinica…
The problem with developing a new antibiotic is that doctors from third world countries will prescribe them like candy - so the bacteria become resistant to it fast. In fact Im very scared when I read that there are plans to use antibiotics "borrowed" from ants, or bees, because probably the antibiotic will be dumped by tons and become useless after 2-3 years, while all the ants or bees in the world die out. Apart fr…
Depending on the country and situation medecine can be pricy and in limited supply, wasting it away becomes a disaster in many more ways than long term resistance.