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Endemic Pathogens Are Making You Crazy and Then Killing You

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Re: Endemic Pathogens Are Making You Crazy and Then Killing You

#51

I have no proof (or way to test this), but I’ve thought for a while that some pathogen has infected a good number of people, and damaged their brains. I find it hard to understand many people’s transition into madness any other way. I am not talking about “I believe bubble up economics you believe trickle down so you’re crazy” kind of disagreements, I mean stuff like “lizard people from planet nibiru are eating the c…

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Re: Endemic Pathogens Are Making You Crazy and Then Killing You

#53
Many methodologies have unintentionally introduced bias, like the article mentions. Another example, ear infections are generally assumed to be caused by bacteria instead of viruses leading to prescription of antibiotics which may cause dysbiosis or antibiotic resistance leading to chronic ear infections and/or digestive issues. Why don’t clinicians test for viruses or parasites first to see if maybe that is weakening the immune system and leading to a bacterial overgrowth?

Re: Endemic Pathogens Are Making You Crazy and Then Killing You

#55

Quoted post unavailable.

> they arent checking people with worms because nobody knows they have worms, thanks to the state of our healthcare I have decent healthcare. I don’t think I’ve been explicitly checked for worms recently. Maybe in the bloodwork? This is honestly one of the better ivermectin hypotheses I’ve come across. It doesn’t deserve to be downvoted, particularly within the context of the article, which set a low bar for evidence…

JumpCrisscross says >"I have decent healthcare."

You thought you had decent healthcare! FTFY!

As a child I lived in the South where parasites are endemic. I had my shit analyzed every physical. I shat in a jar in the comfort of my home and brought it to the physical; the doctor's job was to make slides and search for parasites. It was obvious that the doctor didn't enjoy the tests, much to my amusement.

As an adult I've never had a similar test. Yet I live in a similar climate and often do the same things I did as a child (e.g., walk barefoot, swim in a river, etc.).

I asked my doctors about parasites but they always ho-hummed, claiming any parasitic infestation would show up on blood tests. I think they're wrong and so treat myself to the occasional anti-parasitic.

FWIW it isn't a new "ivermectin hypothesis": it's been discussed ad nauseum, even on HN.

Re: Endemic Pathogens Are Making You Crazy and Then Killing You

#56
post #16

Earlier quoted context omitted.

>Make sense or nah? Nah. Hard nah. I don't quite understand how you went from, "I'm an enthusiastic researcher who enjoys..." to, "Ivermectin works on Republicans because Republicans live in squalor so they have worms but we don't know if Ivermectin actually works against COVID or not because our healthcare system sucks."

We know that ivermectin doesnt work on covid, it works on worms People with worms only notice they have a problem after getting sick with covid How did you read that differently Read it again

This was Scott Alexander's hypothesis btw if you missed this piece on ivermectin from him:

https://astralcodexten.substack.com/p/ivermectin-much-more-t...

"The Summary

Ivermectin doesn’t reduce mortality in COVID a significant amount (let’s say d > 0.3) in the absence of comorbid parasites: 85-90% confidence

Parasitic worms are a significant confounder in some ivermectin studies, such that they made them get a positive result even when honest and methodologically sound: 50% confidence

Fraud and data processing errors are of similar magnitude to p-hacking and methodological problems in explaining bad studies (95% confidence interval for fraud: between >1% and 5% as important as methodological problems; 95% confidence interval for data processing errors: between 5% and 100% as important)

Probably “Trust Science” is not the right way to reach proponents of pseudoscientific medicine: ???% confidence"

Re: Endemic Pathogens Are Making You Crazy and Then Killing You

#57

Earlier quoted context omitted.

> they arent checking people with worms because nobody knows they have worms, thanks to the state of our healthcare I have decent healthcare. I don’t think I’ve been explicitly checked for worms recently. Maybe in the bloodwork? This is honestly one of the better ivermectin hypotheses I’ve come across. It doesn’t deserve to be downvoted, particularly within the context of the article, which set a low bar for evidence…

JumpCrisscross says >"I have decent healthcare." You thought you had decent healthcare! FTFY! As a child I lived in the South where parasites are endemic. I had my shit analyzed every physical. I shat in a jar in the comfort of my home and brought it to the physical; the doctor's job was to make slides and search for parasites. It was obvious that the doctor didn't enjoy the tests, much to my amusement. As an adult I…

I'm wondering how https://en.wikipedia.org/wiki/Helminthic_therapy relates to that.

I've read it can be good for some people with MS. Depends on the sort of worms, apparently.

Quackery?

Re: Endemic Pathogens Are Making You Crazy and Then Killing You

#58

I have no proof (or way to test this), but I’ve thought for a while that some pathogen has infected a good number of people, and damaged their brains. I find it hard to understand many people’s transition into madness any other way. I am not talking about “I believe bubble up economics you believe trickle down so you’re crazy” kind of disagreements, I mean stuff like “lizard people from planet nibiru are eating the c…

https://en.wikipedia.org/wiki/Toxoplasmosis maybe? "Up to half of the world's population is infected by toxoplasmosis, but have no symptoms." (No symptoms that we/they know of but read about how it affects mice. Makes them crazy reckless and wanna go get eaten by a cat.)

Re: Endemic Pathogens Are Making You Crazy and Then Killing You

#59

Earlier quoted context omitted.

Anyone that has had to deal with any sort of customer support after Covid knows that things just aren’t right. It’s like talking to people from another planet. I don’t know if it is Covid brain or what.

It would be interesting to see the interplay of social isolation and the psychological impact of parasites/viruses. The history of population bottlenecks in humans (and other species) might be informative. Social isolation tends to increase when plague wipes out a good chunk of a population (e.g., the black death).

Fun thought: The toxoplasma gondii wants to spread, and it's gonna make its victim go out and socialize, even if that means breaking COVID rules. The more push back there is, the more reckless and crazy the victims get.

https://www.nationalgeographic.com/animals/article/mind-cont... (https://archive.ph/S5nB9)

Re: Endemic Pathogens Are Making You Crazy and Then Killing You

#60

Earlier quoted context omitted.

JumpCrisscross says >"I have decent healthcare." You thought you had decent healthcare! FTFY! As a child I lived in the South where parasites are endemic. I had my shit analyzed every physical. I shat in a jar in the comfort of my home and brought it to the physical; the doctor's job was to make slides and search for parasites. It was obvious that the doctor didn't enjoy the tests, much to my amusement. As an adult I…

I'm wondering how https://en.wikipedia.org/wiki/Helminthic_therapy relates to that. I've read it can be good for some people with MS. Depends on the sort of worms, apparently. Quackery?

There's also the "hygiene hypothesis" which states roughly that early exposure to various pathogens helps the immune system learn what is dangerous and what is not. If you've ever visited someplace like, say, Cambodia (parts of which are underwater much of the year) you were likely impressed by the difference between their children's exposure to the elements and those of most children in the USA.

https://dhvi.duke.edu/staying-home-harming-your-child’s-immu...

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