I remember when Michael J Fox announced that he had Parkinson’s in 1998 https://www.michaeljfox.org/michaels-story He started his foundation to treat/cure the disease. Somehow I thought we’d have had made more progress in 25 years. I also find it interesting to look back at the US national debt and wonder how the world would have been different if we invested more of that into research (e.g medical, pure science, etc…
The thing that causes the symptoms is brain cells dying at an abnormally fast rate.
It's really hard to treat cells dying from poorly understood causes.
The foundation has helped get a number of new drugs approved to help with the symptoms.