Leaving the specific idea of the Lisp Machine aside, today there we have a tremendous advantage over the past when it comes to creating the kind of full, self-consistent systems Lisp Machines -- and systems like Smalltalk or Oberon, etc -- represent. Today we have widely accepted communications and data format standards. This is something that really isolated system diversity in the past, where you were "stuck" in so…
They supported things like TCP/IP, UDP, SMTP, X11, RPC, NFS, DNS, HTTP, ... The machines had C compilers, too.