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BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
51–60 of 73 posts
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#52Earlier quoted context omitted.
This is the kind of education that needs to be done in high school during health and biology classes. We can’t hope the general public will become epidemiologically literate on 240 character tweets and 30-second television quotes. Heck, my old high school biology teacher remains a source of coronavirus FUD, so maybe that’s not even enough.
I think most high school (USA) biology courses probably touch on the concept of viruses? This level of detail was certainly taught in high school Advanced Placement (AP) Biology when I took it many years ago.
I took both high school and university biology. We had two or three chapters on viruses in each textbook. But it was mostly discussed in terms of cellular and chemical levels. It was mostly abstracted from disease and epidemiology. Epidemiological concepts were barely taught, except for maybe a brief mention of exponential growth.
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#53No post body was provided.
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#54I assume this is also part of a product development process: if the EWS flags a particular variant, BioNTech can begin crafting a new vaccine component and have it ready sooner, earning a competitive advantage in the (capitalist) vaccine marketplace.
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#55This is not my area and I read the press release but not the paper -- but I cannot help noticing that they mention a sensitivity/recall number (>90%) but not a specificity or precision number.
Even if you're not trying to be cynical or skeptical about this, when there are this few true positive examples available, how can one plausibly do a good job calibrating such a system?
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#56Quoted post unavailable.
That's what happens when you offer a good product
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#57I'm all for stopping new variants of COVID. Why in the world do we have a treatment for COVID that intentionally creates mutations in COVID https://en.wikipedia.org/wiki/Molnupiravir ? I'm not a doctor but it seems pretty clear to me that Molnupiravir creates a great environment for new variants to arise (along with cancer, but that's another issue).
From the wikipedia page you linked: > Molnupiravir is indicated for the treatment of mild-to-moderate coronavirus disease (COVID-19) in adults with positive results of direct SARS-CoV-2 viral testing, and who are at high risk for progression to severe COVID-19.[1][5] So after the risk of creating mutations in the Covid virus has been assessed and weighed against the chances of patients just outright dying due to not…
Is the risk different from the risks of antibiotics and antifungals with respect to creating resistant strains?
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#58> More than 10,000 novel variant sequences are currently discovered every week and human experts simply cannot cope with complex data at this scale This is interesting. I think the Greek alphabet naming system would lead some people to believe the virus only mutates once every few months. Of course, the reality is that every infected individual will produce hundreds of mutations within their body. I think there's a g…
This is the kind of education that needs to be done in high school during health and biology classes. We can’t hope the general public will become epidemiologically literate on 240 character tweets and 30-second television quotes. Heck, my old high school biology teacher remains a source of coronavirus FUD, so maybe that’s not even enough.
Much of it is already on an optional biology module in my country. Of course we don't do anything quantitative about mutation rates etc, but at least you know what mRNA is instead of relying on politicized news pieces written by someone who doesn't even know what chirality is.
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#59> More than 10,000 novel variant sequences are currently discovered every week and human experts simply cannot cope with complex data at this scale This is interesting. I think the Greek alphabet naming system would lead some people to believe the virus only mutates once every few months. Of course, the reality is that every infected individual will produce hundreds of mutations within their body. I think there's a g…
This is the kind of education that needs to be done in high school during health and biology classes. We can’t hope the general public will become epidemiologically literate on 240 character tweets and 30-second television quotes. Heck, my old high school biology teacher remains a source of coronavirus FUD, so maybe that’s not even enough.
I believe I heard about this in this Radiolab episode from last year. It does a good of explaining how the virus replicates in the body and how it behaves differently if the patient is immunocompromised.
https://www.wnycstudios.org/podcasts/radiolab/articles/dispa...
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#60Is this literally a joke? This might as well be a doomsday machine driven by weak AI selecting new Greek glyphs to drive demand for new superfluous covid vaccines.
I'm fully vaccinated, but more data points to come up with media fear mongering is the last thing anyone in the developed world needs right now.