51–60 of 61 posts
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Trust the doctors! Unless a doctor disagrees with me, then forget that doctor and trust me instead.
It's more like, trust institutional medicine, and if your doctor doesn't, then find a new doctor.
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> only take this medication by prescription from a medical doctor. And, if they prescribe it for treating COVID, look for a better doctor.
Pretty sure if your case of Covid is severe enough to warrant treatment, you will not be calling around looking for a second opinion just because your doc prescribed an Rx that might be “internet controversial”. Frankly I trust my doctor more than I trust FB, YouTube, and the government.
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> only take this medication by prescription from a medical doctor. And, if they prescribe it for treating COVID, look for a better doctor.
Trust the doctors! Unless a doctor disagrees with me, then forget that doctor and trust me instead.
Trial group of 62 patients and no parasite screening in those patients - yawn. But could be interesting grounds for a more significant and controlled study with patients with comorbidities.
If you look on Twitter there are other methodological concerns people have with this study. The more important thing is just that it's relatively old, and there have been meta-analyses done; like, lots of people are studying the ivermectin question, and the weight of the evidence doesn't seem to be positive. Here's Cochran's meta-study; Cochran is, from what I can tell, very well-regarded. It appears to include this…
Separately, I'm having trouble parsing your comment, but I'm curious so I will ask: when you say "the boy rebuts", who is the boy here, yourself? Or..? Maybe I'm just not familiar with this turn of phrase.
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Pretty sure if your case of Covid is severe enough to warrant treatment, you will not be calling around looking for a second opinion just because your doc prescribed an Rx that might be “internet controversial”. Frankly I trust my doctor more than I trust FB, YouTube, and the government.
Well… if we start from the premise I am desperate enough to throw reason out the window, then yeah, why not take horse dewormer, malaria drugs, fish tank cleaner, crystals and prayer?
It’s not just a “horse dewormer” folks, it’s a “people dewormer” that has also been used in anti-viral treatments as well. Argue that’s it’s not effective, but stop pretending that this isn’t a drug that is prescribed to people all over the world.
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If you look on Twitter there are other methodological concerns people have with this study. The more important thing is just that it's relatively old, and there have been meta-analyses done; like, lots of people are studying the ivermectin question, and the weight of the evidence doesn't seem to be positive. Here's Cochran's meta-study; Cochran is, from what I can tell, very well-regarded. It appears to include this…
Your link appears to not work, but for others' convenience I think this is what you meant to link: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD... Separately, I'm having trouble parsing your comment, but I'm curious so I will ask: when you say "the boy rebuts", who is the boy here, yourself? Or..? Maybe I'm just not familiar with this turn of phrase.
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Your link appears to not work, but for others' convenience I think this is what you meant to link: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD... Separately, I'm having trouble parsing your comment, but I'm curious so I will ask: when you say "the boy rebuts", who is the boy here, yourself? Or..? Maybe I'm just not familiar with this turn of phrase.
Sorry, my goofy kid is a graduating biochemistry senior and I keep him around the house for deployment in message board disputes.
But concerning controversy surrounding ivermectin I found this interesting text:
An important controversial point to consider in any rationale is the 5 µM required concentration to reach the anti-SARS-CoV-2 action of ivermectin observed in vitro,17 which is much higher than 0.28 µM, the maximum reported plasma concentration achieved in vivo with a dose of approximately 1700 µg/kg (about nine times the FDA-approved dosification).24 25 In this sense, basic fundamentals for assessing ivermectin in COVID-19 at a clinical level appear to be insufficient. Among other reasons, we believe this might have led WHO to exclude ivermectin from its Solidarity Trial for repurposed drugs for COVID-19,12 which raises questions about the pertinence of conducting clinical studies on ivermectin.
from BMJ, "Misleading clinical evidence and systematic reviews on ivermectin for COVID-19" -- https://ebm.bmj.com/content/early/2021/05/26/bmjebm-2021-111...
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Well… if we start from the premise I am desperate enough to throw reason out the window, then yeah, why not take horse dewormer, malaria drugs, fish tank cleaner, crystals and prayer?
Honestly…people who toss out the whole “horse dewormer” talking point should also refuse to take penicillin if your doctor prescribed it because they also give that drug to horses too. It’s not just a “horse dewormer” folks, it’s a “people dewormer” that has also been used in anti-viral treatments as well. Argue that’s it’s not effective, but stop pretending that this isn’t a drug that is prescribed to people all ove…
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Honestly…people who toss out the whole “horse dewormer” talking point should also refuse to take penicillin if your doctor prescribed it because they also give that drug to horses too. It’s not just a “horse dewormer” folks, it’s a “people dewormer” that has also been used in anti-viral treatments as well. Argue that’s it’s not effective, but stop pretending that this isn’t a drug that is prescribed to people all ove…
I would also add, before you argue that it's ineffective, please consider it in the context of its place in the "triple therapy". We use drug combinations to treat things like cancer and peptic ulcers because of synergies. My understanding is that the ivermectin and doxycycline help zinc to get into our cells and the zinc is what does the work to inhibit virus replication.
BTW, I’m not arguing for or against it for Covid. I am just saying that if my doctor decided to prescribe it for me, I’m going to trust their judgement, because I trust them.
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I would also add, before you argue that it's ineffective, please consider it in the context of its place in the "triple therapy". We use drug combinations to treat things like cancer and peptic ulcers because of synergies. My understanding is that the ivermectin and doxycycline help zinc to get into our cells and the zinc is what does the work to inhibit virus replication.
I think you are going to have a hard time convincing someone who only refers to ivermectin as a “horse dewormer” to think of it beyond whatever their summary talking points tell them. That is why the talking point is to try and mislead folks as it being only a veterinary Rx, they don’t have to go into details…just dump the misinfo out there. BTW, I’m not arguing for or against it for Covid. I am just saying that if m…
It's designed to shut down any reasoned discourse or critical thinking and I'm surprised it's still working.