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Pfizer and Moderna vaccines may produce lasting immunity

nature.com

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Re: Pfizer and Moderna vaccines may produce lasting immunity

#51

Post by jaywalk »

xadhominemx wrote: post #46
crazygringo wrote: post #33

Earlier quoted context omitted.

Good antibody tests are extremely (99%) accurate in verifying previous infection, not sure why you're claiming the opposite...? And while vaccination is safe and easy to get , both me and a lot of my friends were basically as sick as a regular flu for a day or two from it. Some people have no reaction, which is wonderful, but a lot of people need to take a sick day or two, or intentionally get the vaccine on a Friday…

What is the population of people who are willing to get a blood draw for an accurate antibody test but haven’t been vaccinated already and can’t afford moderate flu-like symptoms for a day? I’m sure a small number of people like that exist but it’s not really worth carving out complex exceptions to vaccination rules (specifying which kind of antibody tests administered by who and when, etc.) to accommodate their pref…

I've got a past positive Covid test. If that's not good enough, then why shouldn't every vaccinated person also have to go through the blood draw for an accurate antibody test to confirm their immunity? The vaccines are imperfect, just like all vaccines that have ever been created.

Re: Pfizer and Moderna vaccines may produce lasting immunity

#53

Post by YawningAngel »

mywittyname wrote: post #45
jaywalk wrote: post #8

Earlier quoted context omitted.

It's time for the naturally immune to be treated the same as those who've been vaccinated. There is absolutely zero scientific evidence to the contrary, and plenty of evidence to support it.

Vaccination is more comprehensive than natural immunity though. We've already see that the BNT vaccine offers a higher degree of protection against variants than natural immunity, or indeed other vaccines. Reinfection studies from a few months ago demonstrated that natural immunity is roughly 50% effective for people aged 65 or over. And that's the age group most likely to experience negative outcomes from covid-19,…

It's quite irresponsible to try and coerce people who don't need treatment to accept it as well

Re: Pfizer and Moderna vaccines may produce lasting immunity

#54

Post by kaiju0 »

Has there been any work done on the severity of the COVID 19 variants? My understanding is variants of highly dangerous viruses rarely keep the high level of risk as the progenitors.

Does the delta variant and others pose the same risks? Are we over responding to a virus family group?

Re: Pfizer and Moderna vaccines may produce lasting immunity

#55

Post by delecti »

xxpor wrote: post #24
yazaddaruvala wrote: post #6

Earlier quoted context omitted.

We'll "need" to take periodic boosters to improve Moderna and Pfizer's profit margins. That said, given its safe, I'm happy to do it to help fund / drive investment into the mRNA supply chain.

I'm sorry, but you have no idea how vaccine economics work. Why do you think that researcher had so many problems at Pfizer getting funding to work on mRNA? Drug companies want to invent things like Viagra or Harvoni, not vaccines that are given to everyone a few times.

Hundreds of millions (or billions) of people getting annumal booster shots seems like a pretty good source of recurring revenue.

Re: Pfizer and Moderna vaccines may produce lasting immunity

#56

Post by bryan0 »

enterexit wrote: post #28
RcouF1uZ4gsC wrote: post #5

The mRNA vaccines have been the silver lining to the whole COVID-19 disaster. They seem “unreasonably effective” against COVID, basically if you had a genie that you could ask to make a vaccine, it would be hard to do much better, other than the requirement for 2 jabs. In addition, the mRNA technology has broad applicability to other issues such as other viruses (such as flu) and even cancer!

Does mixing of one mRNA vaccine with another mRNA vaccine for the second does create the same effect as if it's one brand of vaccine was used?

CDC said it was "ok" to do so back in January. In Europe they studied mixing mRNA with non-mRNA doses (astra zeneca and pfizer) and that also appeared to work very well: https://www.pbs.org/newshour/health/a-mix-and-match-approach...

Re: Pfizer and Moderna vaccines may produce lasting immunity

#57

Post by chaostheory »

cdolan wrote: post #17
beervirus wrote: post #3

We’ll still probably need periodic booster shots to deal with variants as they crop up. Still, very encouraging news if it holds up in practice.

Source/Sauce?

I don't know why the original comment is being downvoted. It is not a conspiracy theory to assume that we need booster shots. Is it not like our situation with the flu?

https://www.cnbc.com/2021/04/15/pfizer-ceo-says-third-covid-...

https://www.cnbc.com/2021/06/22/covid-booster-shots-coronavi...

The news of this new study just came out today. Give the guy a break.

Re: Pfizer and Moderna vaccines may produce lasting immunity

#58

Post by raphlinus »

polote wrote: post #41
raphlinus wrote: post #12

Earlier quoted context omitted.

There's very strong evidence, particularly against the Delta variant[1]. That paper cites a 33.5% effectiveness after one dose, compared to 87.9% after two doses of the Pfizer/BioNTech vaccine. [1]: https://www.medrxiv.org/content/10.1101/2021.05.22.21257658v...

But the issue, is that if you had your first dose 2 days before being infected, you count as being infected after 1 dose. We need to compare "1 dose, x days after first dose" and "two doses, x days after first dose" to compare the same thing

That is not consistent with the "Vaccination status" definition in the paper I cited. The tl;dr on that is that "first dose" starts 21 days after vaccination, and "second dose" 14 days after.

Also, to get a better sense of the timeline for vaccination effectiveness, take a look at a chart like this one: https://www.technologyreview.com/2020/12/10/1013914/pfizer-b...

Re: Pfizer and Moderna vaccines may produce lasting immunity

#60

Post by xadhominemx »

EasyTiger_ wrote: post #37
xadhominemx wrote: post #15

Earlier quoted context omitted.

It’s hard to reliably verify previous infection and very safe and easy to get vaccinated, so what’s the point? I’m going to check your profile — 90% chance you spread antivax propaganda. Edit: yup. Every time.

> I’m going to check your profile — 90% chance you spread antivax propaganda. You’re not on Reddit anymore friend

Antivaxxers posing as somber hyper rational types never get held accountable. I’m just doing my part.
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