51–60 of 75 posts
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Wouldn't insurance companies love a lower cost one time treatment?
Doubtful. Insurances dont run at a loss, every penny that goes into them they take a cut as profits. If the treatment is expensive, great! More demand for their product, and even if their cut is the same, their profit and revenue will be greater.
I think originally BioNTech worked on cancer treatments.
Earlier quoted context omitted.
How are the flu vaccines doing this? Nature forces them to have an update cycle reminiscent of the fashion industry.
The have to go through an approval process on every update but AFAICR only with a study including 300 adults, so substantially less then the tens of thousands that were included in the Biontec/Moderna trails.
Earlier quoted context omitted.
How are the flu vaccines doing this? Nature forces them to have an update cycle reminiscent of the fashion industry.
Planning, prediction, and coordination. https://www.cdc.gov/flu/prevent/vaccine-selection.htm#:~:tex... .
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Planning, prediction, and coordination. https://www.cdc.gov/flu/prevent/vaccine-selection.htm#:~:tex... .
That's talking about selection for production, not about development. How is development not part of three scope at all? Are they only selecting amongst a pre-developed library? Do they have a reusable process that goes from strain to vaccine and "just works"? The latter would be very similar to a liberal approach like "we got delivery mechanism for mRNA blueprint of spike protein X approved, we can use the same appr…
https://www.cdc.gov/flu/prevent/how-fluvaccine-made.htm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947948/#irv123...
Can anyone comment on where we would be if COVID-19 hit a few years earlier and mRNA wasn't ready for primetime?
If this hit 20 years ago I suspect that we wouldn't have perceived anything but the tip of the iceberg of people who actually die or get close, because PCR was much less industrialized back then. And the big invisible "underwater part" of young or lucky people who don't get bad Covid but still serve the virus as transmitter relays would have made it a very strong, short wave. Likely mass graves in every part of the w…
The COVID IFR is known to be lower than that of the 1918 influenza pandemic, which killed between 50 and 100 million people in less than a year, and pulled that off at a time when the Earth's population was a quarter of what it is today and much less mobile. I have no idea whatsoever where you get the idea that COVID is worse than 1918. It most emphatically (at least so far) is not at all showing itself to be as bad, let alone worse.
I really hope this mRNA train keeps going and companies succeed executing on it. Does anyone know the status for CRISPR medical technology? I remembering hearing about all these great applications using CaaS-9 and 13 but I haven’t really heard any new medical breakthroughs recently (though the hemophilia “cure” was awesome!).
I really hope this mRNA train keeps going and companies succeed executing on it. Does anyone know the status for CRISPR medical technology? I remembering hearing about all these great applications using CaaS-9 and 13 but I haven’t really heard any new medical breakthroughs recently (though the hemophilia “cure” was awesome!).
I read somewhere recently that CRISPR was actually causing far more accidental mutations than anticipated. Apologies I do not have the source handy, though Google should turn up some information.