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23andMe licenses its own drug compound to Spanish firm Almirall

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Re: 23andMe licenses its own drug compound to Spanish firm Almirall

#51

Post by stanmancan »

toomuchtodo wrote: post #46
stanmancan wrote: post #36

Earlier quoted context omitted.

My concern in these services is, at what point in the future does your DNA get weaponized against you? When do you get declined for health insurance, or have jacked up premiums, because the insurance company bought a report from 23andMe that says you have a predisposition to expensive disease ? My DNA isn't a secret, but I don't yet feel comfortable voluntarily handing it over to be indexed by a for profit company th…

> When do you get declined for health insurance, or have jacked up premiums, because the insurance company bought a report from 23andMe that says you have a predisposition to expensive disease? US federal law prohibits this [1]. [1] https://ghr.nlm.nih.gov/primer/testing/discrimination

The specific insurance example was just a theoretical example. I'm less concerned about someone trying to kill me, there are much easier ways to do that without targeting me based on my DNA!

Re: 23andMe licenses its own drug compound to Spanish firm Almirall

#52

Post by LinuxBender »

chrisamiller wrote: post #31
LinuxBender wrote: post #29

Somewhat off topic: Has anyone yet made a device that is entirely self contained and can do a basic analysis of DNA without sending or fetching data from anywhere? In other words, 100% air-gapped and my DNA and data stay on the portable device. If not, approx. how many years until such a device might exist?

Unfortunately, there still is no such thing as "basic" analysis of DNA. :)Ewan Birney has a great quote about this: Sequencing, analysing and interpreting genomes is ‘routine’ in the same way the US Navy ‘routinely’ lands planes on aircraft carriers. It might happen regularly by well trained crew with the right equipment but it is not an easy thing to do. https://twitter.com/ewanbirney/status/1040144488948281344 That…

This is actually promising. Obviously my mental comparison is not appropriate, but I recall diagnostic equipment for vehicles that cost $500k+ and took up a half of a bay in the shop. Now I can do the same diagnostics with a hand-held device that is $95. That was a 20 year gap. If the same evolution occurs with genetic equipment, it will meet my needs. In 15 to 20 years, I want to acquire a copy of Dr. Sinclairs work on the yamanaka factors and reversing cell age. I will need equipment to see DNA, epigenetic methylation and more.

Re: 23andMe licenses its own drug compound to Spanish firm Almirall

#53

Post by clSTophEjUdRanu »

BitwiseFool wrote: post #2

This is great. I had a 23andMe test done years ago and one of the reasons why I chose to do it was because my genetic data might be helpful for others. I personally don't feel like I 'own' my genetic code and I'm quite happy to let scientists analyze it. However I understand while many people do not feel the same way.

I agree. Your genetic code doesn't define you and I don't see it as private and to be protected. You leave it everywhere you go.

Re: 23andMe licenses its own drug compound to Spanish firm Almirall

#54

Post by clSTophEjUdRanu »

Analemma_ wrote: post #21
BitwiseFool wrote: post #2

This is great. I had a 23andMe test done years ago and one of the reasons why I chose to do it was because my genetic data might be helpful for others. I personally don't feel like I 'own' my genetic code and I'm quite happy to let scientists analyze it. However I understand while many people do not feel the same way.

You might start feeling differently when a new test is developed for existing genetic conditions that it turns out you have, and since your DNA is already public suddenly your health insurance premiums quintuple.

And then the dreaded military industrial police state gestapo drone strike you for not having white enough DNA?

This site is becoming insufferable with the paranoia worst-case-scenario circle jerking. I'm tired of hearing that the sky is falling because 23andme might profit from my DNA.

Calm down.

Re: 23andMe licenses its own drug compound to Spanish firm Almirall

#55

Post by Real_S »

rainyMammoth wrote: post #47
BitwiseFool wrote: post #2

This is great. I had a 23andMe test done years ago and one of the reasons why I chose to do it was because my genetic data might be helpful for others. I personally don't feel like I 'own' my genetic code and I'm quite happy to let scientists analyze it. However I understand while many people do not feel the same way.

23AndMe is reusing the same model as Google with the extra advantage that people are naively ready to pay for it. They have the same privacy issues as Google and I would certainly never trust them with my DNA. I know it's easy enough to get access to it but I'm certainly not going to pay or volunteer to give it. That information is eventually going to get weaponized. What will happen once they manage to statistically…

Here is a study on the genetics of political belief[0]. In summary, there is a large genetic component.

[0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038932/

Re: 23andMe licenses its own drug compound to Spanish firm Almirall

#57

Post by searine »

rainyMammoth wrote: post #47
BitwiseFool wrote: post #2

This is great. I had a 23andMe test done years ago and one of the reasons why I chose to do it was because my genetic data might be helpful for others. I personally don't feel like I 'own' my genetic code and I'm quite happy to let scientists analyze it. However I understand while many people do not feel the same way.

23AndMe is reusing the same model as Google with the extra advantage that people are naively ready to pay for it. They have the same privacy issues as Google and I would certainly never trust them with my DNA. I know it's easy enough to get access to it but I'm certainly not going to pay or volunteer to give it. That information is eventually going to get weaponized. What will happen once they manage to statistically…

>They are hyping consumers by pushing stories of curing rare diseases with the help of statistics.

Except they actually are.

23andMe data has been invaluable in the effort to figure out what is causing complex genetic disease. Here is one I've personally used to research depression : https://www.nature.com/articles/ng.3623

Re: 23andMe licenses its own drug compound to Spanish firm Almirall

#58

Post by klipt »

Real_S wrote: post #55
rainyMammoth wrote: post #47

Earlier quoted context omitted.

23AndMe is reusing the same model as Google with the extra advantage that people are naively ready to pay for it. They have the same privacy issues as Google and I would certainly never trust them with my DNA. I know it's easy enough to get access to it but I'm certainly not going to pay or volunteer to give it. That information is eventually going to get weaponized. What will happen once they manage to statistically…

Here is a study on the genetics of political belief[0]. In summary, there is a large genetic component. [0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038932/

Causal or just correlation?

It's easy to imagine spurious correlation. Eg Italian Catholic populations may be more right wing than British Protestant populations.

But that doesn't mean it's Italian genes making then right wing.

Re: 23andMe licenses its own drug compound to Spanish firm Almirall

#59

Post by bllguo »

Hasz wrote: post #35
Beefin wrote: post #32

Earlier quoted context omitted.

That makes zero sense, the effort is in deriving insights in producing something tangible - drugs. That's like saying you want a cut from all of Google's revenue because you use their search engine, or you want a cut from any service because they use the analytics from your use to improve their product.

That's exactly what I'm saying. I recognize it's not practical, but that doesn't mean I'm going to change the criterion -- it's also why I chose not to upload data to 23andMe. In Google and everyone else's case, I would argue it's a bit different. Google remunerates me with the best search engine in the world, excellent free email, etc. Other services improve the product, which I (generally) reap the benefits of. On…

your data is _not_ valuable per se. it only becomes valuable when aggregated.

Re: 23andMe licenses its own drug compound to Spanish firm Almirall

#60

Post by TheAceOfHearts »

pvaldes wrote: post #26
gpm wrote: post #17

Earlier quoted context omitted.

No one is using the physical objects for their research. They sequenced it (at your request) and are only using the information for research...

This information can be easily used to regenerate partially the physical object.

Are you saying you wouldn't download a car?
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