51–60 of 130 posts
I have the feeling this has much more to do with our self inflicted lifestyle than genetic factors. Maybe no other animal is just that stupid.
Have you ever owned a cat or dog? My experience is that a percentage of them will overeat unless constantly monitored, eat things that are outright dangerous, etc. What is it that makes humans the stupid ones, here?
Earlier quoted context omitted.
I fail to see what this has to do with my comment. The hardening in atherosclerosis is caused directly and exclusively by atheroma.
Everything I've ever read says fatty deposits. The NHS website calls fatty deposits "atheroma". You can find multiple definitions of atherosclerosis/atheroma in other places describing them the same way. Wikipedia says: "While the early stages, based on gross appearance, have traditionally been termed fatty streaks by pathologists, they are not composed of fat cells but of accumulations of white blood cells, especial…
Regarding the mechanism of atheroma formation, I don't have a list of references handy, but maybe this is a good start: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152836/
Also of interest would be the role of high insulin and/or glucose and the damage they can cause to the arterial walls (inflammation is a necessary condition in the formation of atheroma).
It seems that this guys never tried to catch a shrew.
So in what way are "only humans" prone? Are these not heart attacks?
If this turns out to be true, I wonder if this is something CRISPR could fix...
> Interestingly, the evolutionary loss of the CMAH gene appears to have produced other significant changes in human physiology, including reduced human fertility and enhanced ability to run long distances.
Reduced fertility doesn't seem for me important, we have a contraception for that. But enhanced ability to run long distances seems very convenient. I can ride a bicycle or walk for hours just for fun of physical exercise, and I'm not going to lose that.
It seems that this guys never tried to catch a shrew.
I've seen a mouse die in a "humane" trap after being carried a couple blocks – I always understood that was from a heart attack. It seems to happen with birds too – stress them out a bit, then dead. So in what way are "only humans" prone? Are these not heart attacks?
My Dad's heart stopped and he was kept alive by 45 minutes of CPR by burly firefighters - did he have a heart attack? Nope. His heart's pacemaker cells went on the fritz, but it wasn't a myocardial infarction.
A "heart attack" is a myocardial infarction, but many other bad things can happen to your heart.
I like how the headlines explicitly states humans . For yet another study in ... mice. There are other options like dogs and pigs which are much better models for human biology, so if you really want to make a claim about subtle effects of human genetics you need to be as close to a human model as possible. This is entirely ignoring the someone generous leap they make that one single gene mutation is responsible for…
Oh another couch biologist,there's one in every thread.. thanks for all the observations, we really hadn't thought of any of that, you single-handedly salvaged modern biological research !!
I have the feeling this has much more to do with our self inflicted lifestyle than genetic factors. Maybe no other animal is just that stupid.
I like how the headlines explicitly states humans . For yet another study in ... mice. There are other options like dogs and pigs which are much better models for human biology, so if you really want to make a claim about subtle effects of human genetics you need to be as close to a human model as possible. This is entirely ignoring the someone generous leap they make that one single gene mutation is responsible for…
If this withstands scrutiny a chimpanzee study can't be far off, though.
I have the feeling this has much more to do with our self inflicted lifestyle than genetic factors. Maybe no other animal is just that stupid.
And the title is a bit incorrect, other animals do suffer with heart issues/"heart attacks" (usually congenital, but due to old age as well)
I have the feeling this has much more to do with our self inflicted lifestyle than genetic factors. Maybe no other animal is just that stupid.
> Maybe no other animal is just that stupid. Have you ever owned a cat or dog? My experience is that a percentage of them will overeat unless constantly monitored, eat things that are outright dangerous, etc. What is it that makes humans the stupid ones, here?