Does anyone know where to get it in bulk form? The commercial stuff I've seen seems way overpriced. Also, I'm happy for the disclosure but be wary of potential bias... > The study was partially funded by grants from the National Institutes of Health and the American Federation for Aging Research. ChromaDex, the maker of NIAGEN provided supplements and some financial support.
Nicotinamide riboside effects on aging similar to caloric restriction
51–60 of 86 posts
Re: Nicotinamide riboside effects on aging similar to caloric restriction
#52Also, the company ChromaDex seems to have an exclusive right to sell the compound. Anyone think there's an upside to the stock?
Re: Nicotinamide riboside effects on aging similar to caloric restriction
#53Earlier quoted context omitted.
Thanks! we now have the right vowel above.
As long as you're adjusting the title, I'll point out that the study does not actually demonstrate that the effects on aging are similar. Just that taking the pill creates a metabolite that might possibly have an effect on aging.
Re: Nicotinamide riboside effects on aging similar to caloric restriction
#54Does anyone know where to get it in bulk form? The commercial stuff I've seen seems way overpriced. Also, I'm happy for the disclosure but be wary of potential bias... > The study was partially funded by grants from the National Institutes of Health and the American Federation for Aging Research. ChromaDex, the maker of NIAGEN provided supplements and some financial support.
Just use high quality niacin/nicotinic acid/vitamin-b3. "niacin supplementation increases cellular nicotinamide adenine dinucleotide (NAD+) levels" reference: https://examine.com/supplements/vitamin-b3/
Re: Nicotinamide riboside effects on aging similar to caloric restriction
#55Is this the same product that Elysium Health sells? Also, the company ChromaDex seems to have an exclusive right to sell the compound. Anyone think there's an upside to the stock?
Highly doubt there's an exclusive right to sell a compound like this. I know there are multiple suppliers so doesn't seem to be any patents involved.
Re: Nicotinamide riboside effects on aging similar to caloric restriction
#56I think calorie restriction is a more interesting idea, because it forces you to think about eating high-nutrient foods. The first things I did were to eliminate sugars and other processed ingredients, including all flours. Continuing to eat junk and assuming that pills and supplements will compensate for that is probably not a good idea.
Re: Nicotinamide riboside effects on aging similar to caloric restriction
#57Earlier quoted context omitted.
I don't think the average person has access to a Mass Spec or Liquid Chromatography equipment.
https://www.scienceexchange.com $100-150 to run a sample through LC-MS via any one of dozens of small laboratory groups. Most are willing to explain things to a newcomer who is working his or her way through learning the ropes.
Plenty of impurities don't show up in LC-MS.
Re: Nicotinamide riboside effects on aging similar to caloric restriction
#58I think calorie restriction is a more interesting idea, because it forces you to think about eating high-nutrient foods. The first things I did were to eliminate sugars and other processed ingredients, including all flours. Continuing to eat junk and assuming that pills and supplements will compensate for that is probably not a good idea.
Compliance for CR is near impossible though. I'm a believer in it but am still 10 pounds overweight. It won't work for everyone, obviously (because so many of us are overweight).
Re: Nicotinamide riboside effects on aging similar to caloric restriction
#59Does anyone know where to get it in bulk form? The commercial stuff I've seen seems way overpriced. Also, I'm happy for the disclosure but be wary of potential bias... > The study was partially funded by grants from the National Institutes of Health and the American Federation for Aging Research. ChromaDex, the maker of NIAGEN provided supplements and some financial support.
Just use high quality niacin/nicotinic acid/vitamin-b3. "niacin supplementation increases cellular nicotinamide adenine dinucleotide (NAD+) levels" reference: https://examine.com/supplements/vitamin-b3/
Also there seems to be some synergy between Niagen and resveratrol and pterostilbene that I can clearly notice. Foods that work well with Niagen are raisin(-bread) and olive oil. Of course, ymmv.