Earlier quoted context omitted.
So... do you mind answering the second part then? Will they change ycombinator.com to something else if somebody is offended? Or will you change your "smhost" if I'm gonna tell you it offends me?
In Oxford a lot of things are named after "Isis". Isis is the local name for the River Thames, presumably named after the Egyptian Godess. We should not change that name, just because it is used by a terorist group. But it would be a bit distasteful to use it as a new name. Especially if you use it intentionally with the intent of causing offence. Nuance matters.
(I like to imagine all the children telling their parents they were going to London to "study with ISIS" causing huge parental conniptions until the penny dropped.)