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OxyContin's 12-hour problem (2016)

latimes.com

51–60 of 96 posts

Re: OxyContin's 12-hour problem (2016)

#51

I just got ACL surgery and am doing the entire recovery (day 11) without any painkillers stronger than ibuprofin. This is not because I'm so brave, but because I know the pain associated with opioids to be so much than the physical pain in my knee. We've got to aggressively pursue alternatives.

Or maybe your pain is not as severe as the pain for which others take opioids.

Re: OxyContin's 12-hour problem (2016)

#52
post #19

I'm sure this is an easy question to answer, but it was bugging me during the whole article. What's preventing a pill that releases a dose immediately and one after 6 hours? Or something like a diabetic pump that dispenses medication continuously? Surely such systems have the potential to be safer and more effective for patients?

There's fentanyl patches.

Re: OxyContin's 12-hour problem (2016)

#53
Tldr: Oxycontin doesn't last for 12-hours unless doage levels exceed thresholds known to induce addiction and higher risks of death. The 12-hour claim is a marketing gimmick that the company will go to war over regardless of the collateral damage. Moreover, the US court system has repeatedly permitted the company to continue, and works with the company to seal these findings.

Good to know.

Re: OxyContin's 12-hour problem (2016)

#54
post #19

I'm sure this is an easy question to answer, but it was bugging me during the whole article. What's preventing a pill that releases a dose immediately and one after 6 hours? Or something like a diabetic pump that dispenses medication continuously? Surely such systems have the potential to be safer and more effective for patients?

There's fentanyl patches.

Re: OxyContin's 12-hour problem (2016)

#55

Previous discussion has this top comment ( https://news.ycombinator.com/item?id=11652159 ) by cant_kant, which I believe is worth posting here: Sensible doctors do not believe drug company marketing. I get large amounts of ad-junk from drug companies that ends up unread in the bin. I refuse to meet with drug company representatives. I smile politely at them if I bump into them in the corridor and suggest that they le…

By that definition, most doctors aren't sensible.

Re: OxyContin's 12-hour problem (2016)

#56

Previous discussion has this top comment ( https://news.ycombinator.com/item?id=11652159 ) by cant_kant, which I believe is worth posting here: Sensible doctors do not believe drug company marketing. I get large amounts of ad-junk from drug companies that ends up unread in the bin. I refuse to meet with drug company representatives. I smile politely at them if I bump into them in the corridor and suggest that they le…

[deleted]

Re: OxyContin's 12-hour problem (2016)

#57

Previous discussion has this top comment ( https://news.ycombinator.com/item?id=11652159 ) by cant_kant, which I believe is worth posting here: Sensible doctors do not believe drug company marketing. I get large amounts of ad-junk from drug companies that ends up unread in the bin. I refuse to meet with drug company representatives. I smile politely at them if I bump into them in the corridor and suggest that they le…

That sounds like a good, responsible, doctor. I probably wouldn't believe them if they were my doctor. I've been through a repaired Achilles and knee surgery and haven't gone to get the prescriptions filled for any of it. I don't trust any doctor anymore to give me something that is actually good for me - I suspect they're giving me something that's good for them.

I happen to have direct exposure to the medical industry at the practice level. I can tell you unequivocally that entire industry is compromised. Maybe you're a good doctor, and you have my best interests at heart, but you're in the minority, and your peers have ensured I won't be trusting you.

Re: OxyContin's 12-hour problem (2016)

#58
post #8

Published May 5, 2016. Article argues that OxyContin caused strong withdrawal symptoms when used as directed. Important, imo, because at a societal level we substantially blame addiction on "drug abuse" which is not always an adequate model.

> at a societal level we substantially blame addiction on "drug abuse" which is not always an adequate model. While I agree that this model is not accurate, I'd also point out that just because you're taking a drug as directed doesn't mean you're not abusing it. For whatever reason most people in the U.S. seem to have a wildly unjustifiable level of faith in western medicine, either way too much or way too little. Be…

If my doctor tells me to take Pill A every 8 hours, and I do so, how am I abusing it? It might be drug abuse, but it's not on my part.

Re: OxyContin's 12-hour problem (2016)

#59
post #19

I'm sure this is an easy question to answer, but it was bugging me during the whole article. What's preventing a pill that releases a dose immediately and one after 6 hours? Or something like a diabetic pump that dispenses medication continuously? Surely such systems have the potential to be safer and more effective for patients?

Why would it need an automatic pill? What about 1/n dosage taken n times per day? Less convenient sure, but you can pick whatever n works.

Re: OxyContin's 12-hour problem (2016)

#60

Can somebody give some context on the root cause of the problem - the chronic pain epidemic in US. What caused it, why it is more than in other parts of the world and why so many painkillers? Is it cultural?

The book Dreamland covers this quite a bit, and is a good read on the subject:

https://www.amazon.com/Dreamland-True-Americas-Opiate-Epidem...

My takeaway was that opiates were incorrectly classified as a non-addictive way to treat pain, so doctors started dolling them out far too liberally. Hospitals also started employing pain specialists who's sole job was to treat pain in patients. It's pretty easy to find people in any sort of "pain" if that's all you're looking for.

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