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Exercise Tied to Lower Risk for Some Types of Cancer

well.blogs.nytimes.com

51–55 of 55 posts

Re: Exercise Tied to Lower Risk for Some Types of Cancer

#51

Earlier quoted context omitted.

>A sedentary 40 year old looks and feels 20 years older than a 40 year old athlete. This is a completely unsubstantiated claim.

you want a randomized study? :D

Yes, how about taking pictures of a bunch of 40 year old marathon runners and putting it next to a picture showing a bunch of 20 year old overweight accountants and then ask people to guess the average age of each group? That should be pretty simple and covers at least the "looks" claim.

Re: Exercise Tied to Lower Risk for Some Types of Cancer

#52

Results from the source study abstract[1]: " A total of 1.44 million participants (median [range] age, 59 [19-98] years; 57% female) and 186 932 cancers were included. High vs low levels of leisure-time physical activity were associated with lower risks of 13 cancers: esophageal adenocarcinoma (HR 0.58, 95% CI 0.37-0.89), liver (HR 0.73, 95% CI 0.55-0.98), lung (HR 0.74, 95% CI 0.71-0.77), kidney (HR 0.77, 95% CI 0.7…

Phew, 186 thousand cancers included out of 1.4 million participants? I knew cancer was not entirely uncommon but... man. That's a lot of unhappy news. Feels bad to think about. If it is true that exercising regularly reduces the risk of cancer, I wonder what the mechanism is? Exercise builds muscle mass, improves lung capacity... Why would that have anything to do with cancer?

I remember as a kid I used to play soccer 1 hour bike away from home. One week I had a bad flu, but I decided to go anyway. The next day I felt mostly cured. I expected that exhaustion (2 hours biking + 2 hours somehow intensive soccer amongst PE teachers .. really exhausting) would worsen the disease but it did not.

Few times since I could notice that in lesser scales.

Maybe increase blood flow, increased metabolism, endorphins, etc do help keeping your system active instead of going in suspend mode while the immune system reacts alone.

Just yesterday I had this metaphor of biology being a gyroscope, the more it spins the more it can dodge.

Re: Exercise Tied to Lower Risk for Some Types of Cancer

#53
post #50

Earlier quoted context omitted.

>> (HR 0.58, 95% CI 0.37-0.89) Can someone explain the numbers? I read it as risk, sub-population, error margins. Is that right?

HR stands for Hazard Ratio. 0.5 would mean something is half as likely as for the control group, while 2 would mean twice as likely. 0.37-0.89 is the confidence interval at 95% confidence. So it's expected that if the study were repeated many times, the HR would appear to be within that (rather wide) range 95% of the time. This time it's 0.58. The main thing is that the upper bound 0.89 is quite a bit less than 1, so…

Thanks for clarifying.

Re: Exercise Tied to Lower Risk for Some Types of Cancer

#55
post #45
post #8

I think it's pretty obvious. I believe that it is not that exercise helps, but sedentarism is poisonous. A sedentary 40 year old looks and feels 20 years older than a 40 year old athlete.

actually a 40yr old athlete that has already more than 20 year of athlete life behind will have a body in a much more bad shape than a guy who had regular walks and healthy diet.

I'm talking about a healthy athlete, not one that it's into professional sports and actually destroys his body or hearth with substance abuse.
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