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Acetaminophen vs. ibuprofen

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Re: Acetaminophen vs. ibuprofen

#491

Post by wouldbecouldbe »

shankr wrote: post #458
wouldbecouldbe wrote: post #196

Earlier quoted context omitted.

yeah tried to reserve ibu for sleep and during the day walking as much as possible. I know not everyone feels better while walking, luckily I did.

No, moving definitely works. I can almost predict when my sciatica pain will be coming - usually when I work long hours sitting and don't do enough movement. I struggle to be more active than just going to the gym. I think we - those who suffer from herniated disc and sciatica, need to move much more than those who don't.

desk treadmill really helped me

Re: Acetaminophen vs. ibuprofen

#492

Post by throwaway982 »

rramadass wrote: post #18

The following article showing a link between Acetaminophen/Paracetamol usage and decline in positive empathy is highly relevant here; The medications that change who we are - https://www.bbc.com/future/article/20200108-the-medications-... Excerpt: Mischkowski’s own research has uncovered a sinister side-effect of paracetamol. For a long time, scientists have known that the drug blunts physical pain by reducing activi…

[dead]

Re: Acetaminophen vs. ibuprofen

#493

Post by foxyv »

KacharKhan wrote: post #417

Doc here. One thing every single member of the general public needs to get drilled into them: Medical science is NOT intuitive. You cannot just read the mechanism of action of a drug and infer a dozen things from it. A drug's mechanism of action, its indication (when it ought to be used) and its adverse effects CANNOT simply be inferred logically from each other. Biology is orders of magnitude more complex than SE/CS…

I don't know how you MDs/DOs do it. You give a dude medication knowing that it has a small chance to turn his stomach into goo because it will stop his brain arteries from popping like a stress ball in a hydraulic press. Sometimes without knowing how the medication does either thing.

Re: Acetaminophen vs. ibuprofen

#494

Post by brightball »

wallst07 wrote: post #488
brightball wrote: post #357

Earlier quoted context omitted.

I've taken so much Advil/Ibuprofen in my life it would be impossible to count at this point. I always got headaches when I was younger and it didn't really stop until I went to college at a higher altitude. When I go back to my hometown, after a couple of days they come back. Some headaches will go away on their own with water or rest, but others that seem to go from one side of my forehead all the way down the same…

You're incredibly lucky that Advil/Ibuprofen has any affect on your headaches. Imagine getting them every other day and no OTC has any affect. This is me until I went to a neurologist. Botox + Triptans can usually stop mine ~98% of the time.

Man, I am sorry.

Re: Acetaminophen vs. ibuprofen

#495

Post by kazinator »

hilbert42 wrote: post #316
Melatonic wrote: post #175

Earlier quoted context omitted.

I weirdly always found Naproxen much more effective than ibuprofen but also find Celebrex great which seems to further confuse the whole COX 1 vs 2 situation

Recently, I've had to take Celebrex (celecoxib) for a back injury and I've been taking it longer than is normally recommended—and that truly worries me (I've determined I have to come off it ASAP). Where I am (Australia), most doctor's prescriptions that have to be taken long-term are issued as the first script plus five repeats. Not so with Celebrex, a script can only be dispensed three times (3 x pk of 30 200mg cap…

Thanks for that; it's good to know about celecoxib and rofecoxib.

Re: Acetaminophen vs. ibuprofen

#496

Post by themanualstates »

hannob wrote: post #183
throwaway27448 wrote: post #27

Earlier quoted context omitted.

What does ingesting 10g of acetaminophen even look like? I've got to imagine the fatal dose is far, far, far lower with chronic usage. Finding out that people are ingesting grams is profoundly disturbing.

Buy a pack of 20x500mg (just checked, common size in Germany), take 2-3 every half hour for a while. Sure, that's extreme. But if you're unaware of the risks, you feel sick, and you believe it's helping you. I mean, people aren't killing themselves in masses with it, but it happens every now and then. Easily imaginable that one in a few million people will have enough tendency to take more pills and is unaware of the…

And think of the children!

Re: Acetaminophen vs. ibuprofen

#497

Post by themanualstates »

i_think_so wrote: post #157
_--__--__ wrote: post #2

My father, who is otherwise in very good health for a ~60 year old, has severely reduced kidney function from taking an ibuprofen+antihistamine most days of his early life to deal with allergies. I'll second the claim that no doctor at any point in his life had told him the risks of doing that, and many encouraged the use of ibuprofen over any other alternative (including the alternative of not using OTC painkillers…

If there's one thing I'm hopeful for regarding all this AI hype, it's that some day we might actually get the Expert Systems we were promised decades ago. Then, finally, we can stop expecting human doctors to know everything . There's just so much going on inside our bodies and it's unrealistic. I had a relative with a different story in the same theme. It sucks and I want to see this technology do something truly be…

We have this already; the side-effect reporting and post-marketing studies.

Re: Acetaminophen vs. ibuprofen

#498

Post by vanderZwan »

lapcat wrote: post #486
vanderZwan wrote: post #479

Earlier quoted context omitted.

I fail to see where anything I said implied that I disagree with that sentiment. Also, you were arguing we should not listen to pain when it's acting irrational, as in unreasonable. Then you switch to "all minds being irrational", as in actually not rational. That's not the same thing.

I have no interest in playing this silly analogy game. You can't have a "conversation" with your body any more than you can have a conversation with your pet cat. Hey cat, we're trying to save your damn life, so stop resisting the veterinarians and the pills! If you have a point to make, then make it literally, not metaphorically.

I'm sincerely sorry for you if you are suggesting that you are completely unable to communicate with your pet cat or observe its behavior and reason about why it makes sense just because it lacks language. I assume you don't actually have that problem but that is what your comment literally implies.

I made my point and you're ignoring it: you imply that all pain is unreasonable because the body is "irrational". By that logic, you are saying that my earlier example of a sprained ankle hurting when I lean on it means my body is "unreasonable" for signalling that I should not lean on a healing sprained ankle. Quite frankly I think anyone ignoring that and harming themselves more in the process is an idiot.

The example of a cat hissing at the veterinarian because it cannot distinguish the situation from a real threat does not mean that cat's never hiss at real threats. If you cannot even be bothered to tell the difference and blame your cat on every occasion, you're being more irrational than the cat.

Re: Acetaminophen vs. ibuprofen

#499

Post by wallst07 »

brightball wrote: post #494
wallst07 wrote: post #488

Earlier quoted context omitted.

You're incredibly lucky that Advil/Ibuprofen has any affect on your headaches. Imagine getting them every other day and no OTC has any affect. This is me until I went to a neurologist. Botox + Triptans can usually stop mine ~98% of the time.

Man, I am sorry.

Thank you

Re: Acetaminophen vs. ibuprofen

#500

Post by marcogarces »

molf wrote: post #205
marcogarces wrote: post #188

Earlier quoted context omitted.

In mozambique i was committed to the hospital with my liver failing after spending two weeks taking acetaminophen daily because everyone at work got sick and someone had to keep the business up (it was a bank, our IT department was very specific and only 6 people knew that job and everyone got extremely hill). After two weeks, i finally went to the hospital and I couldn't leave; spent the next two weeks fighting for…

That sounds terrible! Glad you made it out alive and hopefully recovered well! Out of curiosity: how much did you take per day?

I think I was taking 3 grams a day, 1g every 8 hours; the day I finally decided to go seek medical help, I felt extremely tired... when I traced back how much I had taken, it was 3 grams in less than 8 hours, but this was due to being extremely tired and exhausted from the fever, which made me "forget". Lesson learned, I now keep a strict journal with all medicine I take.
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