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Pfizer submits Covid vaccine to FDA for approval, to distribute in December

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Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#431

Post by fuzxi »

strombofulous wrote: post #270
unnouinceput wrote: post #117

Earlier quoted context omitted.

Why would you be upset for? It's their life, not yours. Once you get vaccinated, ideally, you get immune to the virus. You neither can develop the disease nor spread it. It's the same as saying you don't want to work with people who didn't got vaccinated by any other number of vaccines (let you search wiki for full list as exercise) and I'm pretty sure it already happened.

Because I don't want to be around people with a disease that's serious enough to shut down our society, if I am only 95% resistant to it

The 95% effective figure refers to the percentage of people who develop full immunity, not how resistant an individual is. A more accurate way of phrasing that would be "[...] if I only have a 95% chance of immunity".

I don't mean to split hairs; the distinction is important.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#432

Post by mindcrime »

floatingatoll wrote: post #252
mindcrime wrote: post #208

Earlier quoted context omitted.

https://en.wikipedia.org/wiki/Tacoma_Narrows_Bridge_(1940) It was fine... until it wasn't (four months later). Anyway, this analogy is silly. Neither software nor bridges is exactly like the human body and the myriad of complex interactions that happen within. At the end of the day, all I'm saying is that A. under normal circumstances, it takes a lot of time to get a vaccine tested and approved - for good reason. And…

You’re suggesting that people prioritize decisions based on individual uncertainty over decisions based on public good. That the logistics of distribution will result in the same outcome as your suggestion does not mitigate the perceived selfishness of your suggestion.

That the logistics of distribution will result in the same outcome as your suggestion does not mitigate the perceived selfishness of your suggestion.

I could not care less about anyone's opinion of my "perceived selfishness".

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#433

Post by mindcrime »

ghaff wrote: post #390
mindcrime wrote: post #150

Earlier quoted context omitted.

You would be foolish not to get vaccinated given what we know about COVID. Nobody said anything about not getting vaccinated. The point of discussion here is about not rushing to do it the first day the vaccine is available.

So if not Day 1, when? 6 months out, 1 year out, 2 years out, 10 years out? What arbitrary standard should those who are concerned about long-term effects apply?

That's up to the individual to decide. I'm not trying to be prescriptive here: I"m talking about what I would do. If you want the vaccine on Day 0, by all means, do it. Risk tolerance is obviously a very personal and subjective thing, so "you do you".

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#436

Post by stjohnswarts »

grezql wrote: post #59
baybal2 wrote: post #27

Earlier quoted context omitted.

Because China already has a "national" vaccine, and they see no chance getting through Chinese bureaucracy for such a politicised deal?

"yes you can sell here, we only need to know the ingredients and know-how of this vaccine to approve its safety"

Don't worry they already have it in hand and analyzing it I would be willing to bet.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#437

Post by stjohnswarts »

diag wrote: post #259
bluGill wrote: post #137

Earlier quoted context omitted.

Too late for that - the beta testers have already found it good. A phase 3 trial is beta test.

Phase 4 is like the RC, and by that point it seems to be pretty stable.

I think they add more age groups and diversity as a followup.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#438

Post by stjohnswarts »

jdndbfbf wrote: post #140
bluGill wrote: post #137

Earlier quoted context omitted.

Too late for that - the beta testers have already found it good. A phase 3 trial is beta test.

I'll let you test it for me and find out what the long term effects are.

Go ahead and keep doubting science. I hope that you are hunkering down in the interim and not a mask-denier.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#439

Post by [deleted] »

splonk wrote: post #420
PandawanFr wrote: post #386

Earlier quoted context omitted.

I am guessing this is the one: https://www.medrxiv.org/content/10.1101/2020.08.14.20175257v...

Pretty interesting paper, although I'm not sure it's the one OP was referring to. It's a pretty short paper with a whole pile of graphs at the end, so I encourage people to read it themselves. Quick notes from skimming: - Treats it as an optimization problem for various levels of vaccine efficacy (10-100%), availability(10-100%), spread rate (R0 in {1.5, 2, 2.5, 3}), susceptibility to infection and symptomatic infect…

[deleted]

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#440

Post by Irene »

splonk wrote: post #420
PandawanFr wrote: post #386

Earlier quoted context omitted.

I am guessing this is the one: https://www.medrxiv.org/content/10.1101/2020.08.14.20175257v...

Pretty interesting paper, although I'm not sure it's the one OP was referring to. It's a pretty short paper with a whole pile of graphs at the end, so I encourage people to read it themselves. Quick notes from skimming: - Treats it as an optimization problem for various levels of vaccine efficacy (10-100%), availability(10-100%), spread rate (R0 in {1.5, 2, 2.5, 3}), susceptibility to infection and symptomatic infect…

Yes, there could be many different scenarios; when vaccine supply is limited, vaccinate those at risk of death. BioNTech claims their vaccine efficacy is consistent across age groups, but we won't know for sure until large clinical trials are completed. Also, older people are less willing to be vaccinated earlier. More variables to include in the model...
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