Has no one watched Resident Evil?
Covid vaccine: First ‘milestone’ vaccine offers 90% protection
431–440 of 1001 posts
Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection
#432Good: + ~90% of individuals achieve immunity. + no significant side-effects. Not so good: - two doses needed, 3 weeks apart, immunity after one month from first dose. Slow rollout. - -80C storage and transport needed. Challenging, but doable in developed countries, but still may slow down mass rollout. Not feasible in many developing countries. I still wonder about long-term immunity. Anyone can share any insight?
I believe that temperature is achievable with fairly simply-insulated dry ice containers, in situations where mechanical cooling is not feasible. https://www.nytimes.com/2020/09/18/business/coronavirus-covi... I guess you should invest in dry ice manufacturing companies!
Yes. Pfizer have published info on their logistics, there are details in the wall st journal. Basic idea is a little box of ~1000 doses goes in a big box filled with enough dry ice for up to ten days. Average delivery time will be around 3.
edit: See https://www.wsj.com/articles/pfizer-sets-up-its-biggest-ever...
Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection
#433Earlier quoted context omitted.
This is great and all, and I'm not against vaccinations, but is this safe long term? Am I the only one here who doesn't want to get inoculated in basically the first batch?
Have there historically been issues with vaccines causing problems for the long term that didn't show initially? I've never heard of such a thing, but then again I have only a surface understanding of vaccines.
Pandemrix causing narcolepsy comes to mind: https://www.who.int/vaccine_safety/committee/topics/influenz...
Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection
#434Earlier quoted context omitted.
Warp Speed didn't contribute to the development of this one; they have allocated funds to buy the vaccine though Operation Warp Speed, the federal effort to rush a vaccine to market, has promised Pfizer $1.95 billion to deliver 100 million doses to the federal government, which will be given to Americans free of charge. But Dr. Jansen sought to distance the company from Operation Warp Speed and presidential politics,…
I see your point, but it seems to be overstated as having a promised $2B out there surely had a positive impact.
That's just normal pre-purchasing, though, which would have happened regardless of that particular program. They also have a few hundred million doses ordered by the EU.
Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection
#435I'm currently recovering from Covid-19 and hopefully won't need it, however this line sounds a bit strange:
"It uses a completely experimental approach - that involves injecting part of the virus's genetic code - in order to train the immune system."
I did my flu (not Covid) vaccine shot about 3 weeks ago, just before catching the nastier one, and according to the doctors it works exactly that way, although this one of course doesn't contain parts of SARS-Cov2 but rather various other winter flu virii (H1N1-pdm09,CNIC1909,H3N2,IVR-208, etc).
So if the approach is the usual one, testing is likely where the most time is spent; that should speed up production a lot.
Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection
#436Earlier quoted context omitted.
The latest data (preprint, not peer reviewed etc etc) mention memory B and T cells up to 8 months after recovery from the illness. This means that an immunity of one year is probably likely. This would be probably enough to quench the spread, but not to eradicate the virus.
This is incorrect. They tested SARS patients over 17 years later and they still exhibited an immune response. As long as SARS-CoV-2 doesn’t mutate dramatically the body probably has long term immunity.
There was some response. Was it sufficient or not - it has never been verified. Attempts to vaccinate animals with SARS vaccines ended with terrible outcomes of ADE.
Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection
#437Good: + ~90% of individuals achieve immunity. + no significant side-effects. Not so good: - two doses needed, 3 weeks apart, immunity after one month from first dose. Slow rollout. - -80C storage and transport needed. Challenging, but doable in developed countries, but still may slow down mass rollout. Not feasible in many developing countries. I still wonder about long-term immunity. Anyone can share any insight?
Also not so good: this is a corporate press release. The data will come later.
Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection
#438Earlier quoted context omitted.
>I'm feeling a deep-seated wave of relief that I never thought possible. Like waking up from a year-long nightmare. Thank God. Moderna is also only weeks behind Pfizer/Biontech here with a very similar technology and manufacturing capability of hundreds of millions of doses. We'll be seeing the first EUA's by December, and shots in the arm before the end of the year. Pretty incredible that we can just science our way…
This is great and all, and I'm not against vaccinations, but is this safe long term? Am I the only one here who doesn't want to get inoculated in basically the first batch?
Risk of COVID19 long term effects is far worse than mRNA side effects IMO.
Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection
#439Earlier quoted context omitted.
>I'm feeling a deep-seated wave of relief that I never thought possible. Like waking up from a year-long nightmare. Thank God. Moderna is also only weeks behind Pfizer/Biontech here with a very similar technology and manufacturing capability of hundreds of millions of doses. We'll be seeing the first EUA's by December, and shots in the arm before the end of the year. Pretty incredible that we can just science our way…
This is great and all, and I'm not against vaccinations, but is this safe long term? Am I the only one here who doesn't want to get inoculated in basically the first batch?
> but is this safe long term
Is getting COVID safe long term? There are plenty of viruses that cause issues in the long term. HIV causes AIDS, HPV and Hepatitis cause cancers years later. We have no clue on the long term effects of SARS-Cov-2, other than that it causes COVID-19 in the short term.
It's a choice between the pest and the cholera at this point.
Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection
#440Still plenty of challenges considering you need to store in -80C. Possible in developed countries, but I doubt if it’s doable in developing countries.
Definitely a step in the right direction though