Products I Wish Existed • Hacker News Board

Re: Products I Wish Existed

#431

Post by henryfjordan » Thu, Jan 09, 2020, 12:38 AM UTC

harrisreynolds wrote: post #355

henryfjordan wrote: post #251

Earlier quoted context omitted.

Airtable did some great work on the UX. Introducing people to table schemas with typed columns is pretty awesome, and the creative way they've leveraged that with the little tab that comes out of the side for either a nice view over the data (e.g. a map for an address column) or for showing Pivot Tables/Aggregations. They deserve some design awards for those ideas. But it's not a great alternative to a DB. It's reall…

Airtable has done a great job with their UX! I've started working on a similar platform where the goal is to make building CRUD apps wildly simple. The plan going forward will be to layer on more sophistication after the core foundation is extremely solid. The platform uses Mongo for the dynamic data tables which is a game changer for tools like this. Postgres jsonb data would also work, but Mongo just feels more nat…

Hey I made an account but only see

> You have not created any apps yet.

with no way to create an app that I can see

Re: Products I Wish Existed

#432

Post by mmckelvy » Thu, Jan 09, 2020, 1:03 AM UTC

davedx wrote: post #377

80386 wrote: post #336

Earlier quoted context omitted.

What about a spreadsheet program that can be scripted with Javascript? JS is nice because all you need to write it is a text editor and a web browser, both of which just about all computers have. I had an entry-level job that involved a computer once and automated a lot of the painful stuff with JS - I bet that if more people knew JS, more people would do the same. I don't know if that'd be a good business propositio…

Google Sheets uses JavaScript as its scripting language. The problems I've had there are related to how complicated it is to get data in and out of Sheets. If you want to update a sheet you own, you need to do a full blown OAuth2 implementation.

Excel has an JavaScript API now as well right? At least I heard rumblings to that effect. Not sure how hard / easy it is to get data into / out of though.

Re: Products I Wish Existed

#433

Post by aaavl2821 » Thu, Jan 09, 2020, 6:06 AM UTC

eladgil wrote: post #144

aaavl2821 wrote: post #64

There are biotech startups working on all of those already There are a couple interesting gene therapy companies workout on hearing (akuous and decibel among others). Lots of ophthalmology gene therapy companies also, as well as more traditional companies. Hair regeneration has been a popular area of research for a while Most companies work on biomarkers as part of the drug dev process. However building a business ar…

Which of these do you think are farthest along? Gene therapy seems to be working a little bit in ex-vivo approaches (you take cells out, modify them, and put them back in, largely in the immune system) but progress elsewhere is very limited.

Re akuous and decibel, I don't know too much about their programs

Re eye diseases / blindness, there is at least one approved gene therapy for a form of congenital blindness, luxturna: https://www.fda.gov/news-events/press-announcements/fda-appr...

the eye is one of the areas where gene therapy delivery is currently feasible. other areas include the CNS using AAV9. Perhaps the most impactful gene tx yet approved is Avexis' Zolgensma (Avexis was acq by Novartis for $8-9B in 2018). Zolgensma is a potential cure for spinal muscular atrophy, the leading genetic cause of infant death. Zolgensma did $160M in its first full quarter on the market

Other areas where we will likely see approved gene therapies soon include blood diseases like hemophilia, beta thalessemia. In addition to blood, eye and motor neurons, the liver is a popular target for gene therapy as all of these tissues are easier to deliver gene tx to with current technology

Delivering gene tx to other tissues is not really feasible as far as i know at this point

Re: Products I Wish Existed

#434

Post by twojacobtwo » Thu, Jan 09, 2020, 5:18 PM UTC

reportgunner wrote: post #427

gkfasdfasdf wrote: post #399

Earlier quoted context omitted.

> No VBA FWIW Google Sheets does have the ability to write macros in JavaScript. They even have an npm tool [0] that will let you edit offline via your preferred IDE and then push to your sheet. [0] https://developers.google.com/apps-script/guides/clasp

I'm not saying JS is better or VBA, but JS is definitely not VBA.

Gsuite uses 'Apps Script'[1], not pure JS, so it is quite similar in function to VBA.

[1]https://developers.google.com/apps-script