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What Ozempic does to the gut-brain axis
411–420 of 555 posts
Re: What Ozempic does to the gut-brain axis
#412Earlier quoted context omitted.
Why does there have to be a downside? What was the downside of washing hands before surgery?
One argument would be that Ozempic doesn't give your body any additional resources. It just triggers your body to behave in a different way. But if the changes it causes are universally good, why didn't evolution already make your body work that way? I suppose the counterargument would be that modern life is different from the evolutionary environment, and so it's possible for a change to be beneficial now that wasn'…
There are people with more or less sensitive GLP-1 receptors today, who have lesser or greater impulsivity. If some event occurs where only those with lower impulsivity survive, then the future population will have more sensitive GLP-1 receptors.
This is the only way that happen - noticeable evolution is always driven by population bottlenecks or strong selective pressure. In the absence of those, mutation just keeps expanding the gene pool so more different candidates are available for the next bottleneck.
In case an event happens where only red-haired people survive, good thing some are available, otherwise there's no reason to think everyone will have red hair in the future.
Re: What Ozempic does to the gut-brain axis
#413What’s the downside to this magical drug. There has to be a downside…
the downside is it allows us to continue to avoid solving the real problem ideologues will tell you this is that all mankind suddenly lost their ability to exert self-discipline a few decades ago science points to a broad combination of things like corn syrup and seed oils simply making food too addictivly-rewarding and calorie rich for our nervous and endocrine systems to handle. so, do we reform the farm bill and f…
No one is steering the ship. You have the same right to try to fuck over Pepsi (which owns like half of all addictive food brands) by taking GLP1RAs as they do to try to fuck you over by putting who knows what in their food.
Some of that stuff they put in food is probably designed to antagonize your GLP-1 receptors, you know. They didn't know what those were, but they did know when they put it in food, you bought more! *cough* Pringles
Re: What Ozempic does to the gut-brain axis
#414What’s the downside to this magical drug. There has to be a downside…
The downside is that they make you eat less thereby taking away one of the few things that make life worth living.
You should get in touch with a therapist to help you find meaning in life that isn't just eating food. Or get a girlfriend - i heard that helps most people.
Re: What Ozempic does to the gut-brain axis
#415so, the whole mouse thing is a scam, and now they are openly testing on us, first, and publishing in psychology today to see if we notice.fiendish.
all of life is an experiment. If you're religious, you might consider evolution as a god. If not, just know there are so many random variables that everyone is a unique experiment with sample size of 1.
Re: What Ozempic does to the gut-brain axis
#416Earlier quoted context omitted.
The downside is that they make you eat less thereby taking away one of the few things that make life worth living.
You should get in touch with a therapist to help you find meaning in life that isn't just eating food. Or get a girlfriend - i heard that helps most people.
Ah yes, a therapist. One of those people who will try to gaslight you into thinking spending 40 hours a week in dayprison is a meaningful life.
Re: What Ozempic does to the gut-brain axis
#417Earlier quoted context omitted.
Even if there are zero effects other than the advertised weight reduction, one downside is obvious from the comments here - some people will stop exercising. While exercise has many positive effects, which I'd argue are more important than the weight loss, the latter is the primary reason many people exercise and likely to stop when given the weight loss by other means.
> one downside is obvious from the comments here - some people will stop exercising. Is there any source on this? The precise opposite has happened in my experience. I was an early evangelist for these drugs, and have many dozens of people who I talk to regularly who have since taken them over the years. I cannot think of a single person who went from regular exercise to reducing or eliminating it after taking the dr…
>> one downside is obvious from the comments here - some people will stop exercising.
>Is there any source on this?
Other than the people saying they hate exercise and are glad they can take a drug instead in the comments here? This https://sciencesources.eurekalert.org/news-releases/1130958 for example.
>You would be making an argument contrary to most established science on the topic. Exercise is important and quite beneficial to health. Obesity is far worse.
Is there any source on this?
Re: What Ozempic does to the gut-brain axis
#418Studies show almost all subjects regained the weight and reversed gains within 2 years. This means underlying issues (e.g., food addiction) aren't being addressed. Short of changing habits, the only maintenance solution is lifelong drug use and that doesn't sit well with me.
Why not? People take depression meds, blood pressure meds, all kinds of meds for their whole life. I'll be on omeprazole for reflux my whole life. It doesn't solve the underlying problem of my gut being prone to overpumping acid into my stomach. So omeprazole is problematic? The underlying issue is being treated, it's treated by taking the drug. It works. It's doing its job. I'd be curious as to how you came to this…
First, I agree with your comment.
But since you specifically bring up omeprazole: I backed off of pantoprazole by getting a prescription for half-dose pills (since they're time released, you can't just cut them in half), then decreasing frequency (alternating days, then tapering off) and retained the benefits.
There are plenty of confounding factors in my case, but checking occasionally if you can back out of a drug is worthwhile.
Re: What Ozempic does to the gut-brain axis
#419The more I hear about GLP-1 drugs, the more I think there is something to the joking suggestion of putting it in the water supply.
Thank god I have RO at home with people suggesting things like this.
Positive or negative, I don't want drugs in my water.
Re: What Ozempic does to the gut-brain axis
#420Earlier quoted context omitted.
You should get in touch with a therapist to help you find meaning in life that isn't just eating food. Or get a girlfriend - i heard that helps most people.
Ah yes, a therapist. One of those people who will try to gaslight you into thinking spending 40 hours a week in dayprison is a meaningful life.
So tell me more ;)