GLP-1 drugs: An economic disruptor? (2024)

Post by L-four » Sun, Mar 02, 2025, 3:29 AM UTC

j-bos wrote: post #403

cj wrote: post #19

I started Tirzepatide 3-4 weeks ago. (Mostly as an experiment to understand the hype around GLP's... I don't have diabetes and only very slightly overweight at 20% body fat). Even at the lowest 2.5mg starter dose which you're only allowed to stay on for 1 month: - Extreme appetite suppression to the point where I've started calorie counting specifically to make sure that I'm eating enough. It's incredibly easy to for…

This sounds like my whole life, I've always been trim and have never understood the joy people get from food. Facinating to see there's a drug that recreates that physiology.

Post by bobsmooth » Sun, Mar 02, 2025, 3:33 AM UTC

fonkyyack wrote: post #179

rsync wrote: post #28

The real trend is deflation. People are having fewer children. Fewer miles are driven to fewer offices for fewer trips in cars. Fewer impulse buys are being made and fewer dollars will be made by advertisements (according to the ops conjecture). This is not inflationary. It is the opposite. We live in a deeply deflationary world and we should not be confused by the local, transitory inflation that we may be experienc…

This! Consumption is made of impulse choices. (most of the times). Also we are having fewer children, does this drug reduce also the impulse of having sexual desires? In that case that would be even worst.

Post by toast0 » Sun, Mar 02, 2025, 3:33 AM UTC

MostlyStable wrote: post #71

willis936 wrote: post #59

Earlier quoted context omitted.

It isn't. 20% body fat is 6% below average. That isn't "merely overweight", it's likely underweight. No, I don't think underweight people should take appetite suppressants and I don't think that qualifies as a hot take. I think anyone who is medically overweight (which is a very modest BMI qualifier for anyone with any amount of muscle) should have the choice. Many US medical systems and insurers agree, which is a go…

>it's likely underweight. The only way this can possibly be correct is if you think that the "correct" weight is whatever the population average happens to be which is just...wild to me. If we assume commenter is male (a statistical likelihood), then 20% is the high end of normal, and could very safely be halved. In the less likely case that they are female, then it is right in the middle of the normal range, and cou…

Post by ValleZ » Sun, Mar 02, 2025, 3:39 AM UTC

valunord wrote: post #288

no_wizard wrote: post #279

Earlier quoted context omitted.

Ozempic has been in use for diabetic patients for at least a decade if you want to look at the research of its long term results in that population - which is fairly large to constitute a good sample sizing.

So that means we'll have a good twenty years of data to finally look at, which is what I was saying. I do not trust any medicine unless it has far more data than what we have in this regard at this point. I work in a related field and I can simply say most things we trust should not be trusted and should require far more testing.

Post by a_wild_dandan » Sun, Mar 02, 2025, 3:45 AM UTC

appleorchard46 wrote: post #334

Obesity causes many health problems, but it's also a symptom - of our poor relationship with food, of the way American society is set up around instant gratification, of the predatory nature of food manufacturers. Though treating the symptom is undeniably good, it also lets the deeper problems that lead to it go unchecked, and my fear is that it will lead to novel problems down the line. How recreational drugs are be…