Back in the day I used Linux for rendering my Blender animations because my tests had shown it was 10% faster than the same machine running Windows 10. With render times of more than 8 days this quickly paid off.
I noticed that AMD/Xilinx Vivado synthesis runs 20% faster on WSL2 than on Windows. After seeing such differences using it on plain Windows becomes unpleasant.
Yeah, when I was doing more of that sort of thing I'd generally use ISE or Vivado on a big Ubuntu server and VNC or X-forward it to my machine (the X forwarding could be a bit janky with Vivado but it was OK for getting things going in a pinch).