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South Africa’s omicron coronavirus outbreak subsides as fast as it grew

washingtonpost.com

411–420 of 515 posts

Re: South Africa’s omicron coronavirus outbreak subsides as fast as it grew

#411

I’ve been tanking some downvotes for the past few days for saying this. Disease spread is only exponential for a brief initial period. It is not a good mental or even general model for how disease spreads. We have two years of observational covid data that shows this to be true. Spread slows down rapidly long before reaching 100%. People hear “5x as infectious” and reason that due to the nature of exponential models,…

Thank you. It is mind boggling to me how politicians and scientists (well, mostly MDs) keep talking about exponential growth and make horrible predictions, without realizing that exponential growth is never sustainable - a logistic growth is what often happens in reality if resources are limited.

No post body was provided.

Re: South Africa’s omicron coronavirus outbreak subsides as fast as it grew

#412
post #274

Earlier quoted context omitted.

Its almost as if I live in and am registered to vote one of the few major counties and states that are prone to reintroduce restrictions, and am not currently physically there right now. The goal being that there would eventually be one less county and state that would consider restrictions.

From what you’ve said, you don’t live there any more. But this doesn’t seem constructive so we can let this go.

It confused me as well, but I think the “one of them” isn’t bound to the same specific one as “any of them”.

E.g. “I’m from New York. If any of New York, Chicago, LA, Atlanta [etc.] shut down, I’ll move back to New York and [etc.]”

Re: South Africa’s omicron coronavirus outbreak subsides as fast as it grew

#413

This is fantastic if it happens elsewhere as well. The only reason I am not super pumped is because SA is in Summer, and we’ve seen that sars-cov-2 is impacted my seasonality

In hot places with widespread air conditioning there is also usually a summer peak (people go indoors and close windows, just as they do in cooler places in winter). SA has had peaks in both winter and summer.

Air conditioning is rare in South African homes. They keep cool in the summer by opening their windows and doors, and with swimming pools.

South African businesses, however, almost all have air conditioning.

Re: South Africa’s omicron coronavirus outbreak subsides as fast as it grew

#414
post #42

Earlier quoted context omitted.

It has been discussed many times before - the issue with the SA data is that 80% of the population have been exposed to the virus (either had it or have been vaccinated) so the deaths not budging there can be very misleading for countries with lower vaccination rates.

Wait, natural immunity is real?

Yes, there's definitely some degree natural immunity. There's mixed evidence as to whether it's stronger[0] or weaker[1] than full vaccination, but it's definitely better than nothing.

[0] https://pubmed.ncbi.nlm.nih.gov/34735425/

[1] https://www.medrxiv.org/content/10.1101/2021.09.12.21263461v...

Re: South Africa’s omicron coronavirus outbreak subsides as fast as it grew

#415

Earlier quoted context omitted.

There is a lot to unpack but I doubt you are as right as you think you are. For instance in new variant outbreaks there ate usually harsher responses than for known variant outbreaks, so it is very difficult to identity the real infectivity. But more importantly it's well established that diseases that those diseases spread most widely that don't kill rapidly (or that more generally don't have severe symptoms) and th…

COVID isn't particularly deadly. The selection pressure that can cause a virus to become weaker is mediated by the virus dying off in the corpses it creates. People aren't dropping like flies from COVID, so that selection pressure isn't there, and the virus is free to mutate into more virulent forms. There's no reason to expect a relatively mild, yet still deadly, virus to become weaker, especially if our medical inf…

No post body was provided.

Re: South Africa’s omicron coronavirus outbreak subsides as fast as it grew

#416
post #388

Earlier quoted context omitted.

What you're saying is supported by the data, but do you (or does anyone) know why infections slow down when they do? I can't think of any intuitive reason for it, and haven't been able to find an explanation why the waves crash, so to speak.

My guess is the non-uniform nature of the graph of human contacts, which is probably made up of several densely-connected clusters each with relatively weaker links to other clusters. E.g. let’s say there is an office where everyone works in person and a bar with a group of regular customers. If someone in the office gets Covid, everyone in there has some decent chance of getting it. Similarly, if a bar regular gets…

Thank you for explaining, that sounds highly plausible!

Re: South Africa’s omicron coronavirus outbreak subsides as fast as it grew

#417
post #416

Earlier quoted context omitted.

My guess is the non-uniform nature of the graph of human contacts, which is probably made up of several densely-connected clusters each with relatively weaker links to other clusters. E.g. let’s say there is an office where everyone works in person and a bar with a group of regular customers. If someone in the office gets Covid, everyone in there has some decent chance of getting it. Similarly, if a bar regular gets…

Thank you for explaining, that sounds highly plausible!

For what it’s worth, this is just my personal intuition — I’m not an expert in any of the relevant fields.

Re: South Africa’s omicron coronavirus outbreak subsides as fast as it grew

#418

The panic surrounding Omicron is absurd. Take a look at these two charts. Omicron cases spiked in SA. Deaths didn't budge. At all. https://i.imgur.com/TgRmz4F.png [1] Omicron is a good thing, if your baseline is Delta. But I'm still waiting for the US media stop hyperventilating about it. 1. https://graphics.reuters.com/world-coronavirus-tracker-and-m...

People come up with endless excuses to remain hysterical. There will never be enough evidence to show omicron is less severe. There is always some excuse as to why some data should be discarded or is not applicable. But when it comes to bad news, no evidence needed at all. Some people just want the world to continue burning.

People want to believe the headlines that confirm their prior beliefs, when if you read the actual research reports your will find that there is still just a lot of uncertainty on the question of intrinsic severity.

Those that want to report that omicron is milder focus on overall stats and average symptoms, and gloss over confounding factors.

Those that want to report that it’s just as severe as delta seem to be just picking up the status quo of poor science journalism, and equating “insufficient evidence” with “conclusive there’s no difference”.

This preprint from today out of SA lays out some prospective good news, but still with a lot of uncertainty over how much the lower severity is intrinsic vs mediated by prior infection/vaccination. And there are plenty of limitations, not least of which that their study only includes confirmed omicron infections up to the end of November (they study hospitalizations, and even had to prune their dataset because some patients are still in hospital).

There is just legitimately not enough data yet to answer the questions that most need answering.

https://doi.org/10.1101/2021.12.21.21268116

Re: South Africa’s omicron coronavirus outbreak subsides as fast as it grew

#419

I’ve been tanking some downvotes for the past few days for saying this. Disease spread is only exponential for a brief initial period. It is not a good mental or even general model for how disease spreads. We have two years of observational covid data that shows this to be true. Spread slows down rapidly long before reaching 100%. People hear “5x as infectious” and reason that due to the nature of exponential models,…

A place where it hit exponential levels with really bad results is here in NY at the beginning. We had no precautions, testing, or vaccines in place yet, and hospitals were overwhelmed. It was honestly a scary time. That was where we started "flattening the curve". Now with vaccines available if there are surges and they are not literally building hospitals on fields like they were near me that is something we have t…

> A place where it hit exponential levels with really bad results is here in NY at the beginning.

Or Italy where they had to call in the military to cart away corpses:

* https://www.cnbc.com/2020/03/19/italian-army-moves-coronavir...

Re: South Africa’s omicron coronavirus outbreak subsides as fast as it grew

#420
post #50
post #14

Am I the only one who reads these less than scientific articles as much more than wishful thinking? I mean, I hope this pandemic comes to a close as much as anyone but so many of the recent news articles about the omicron variant being our collective way out of this pandemic seem a bit premature. I understand the theory that viruses become more contagious and less deadly over time but is there an real, peer reviewed…

There is a recently released preprint that concludes that omicron-infected have an 80% reduced likelihood to be hospitalised compared to non-omicron infections. https://www.medrxiv.org/content/10.1101/2021.12.21.21268116v... Of course, it's not yet peer-reviewed, and doesn't model the possible outcomes based on the conclusions, but it certainly seems to be great news.

This paper is interesting and I agree seems like good news. It was posted yesterday BTW.

There is a wrinkle though: the 80% reduction in hospitalizations is compared to this summers delta infections, but they found no difference in hospitalizations compared to non-omicron infections this November (the time period of the study).

They have some discussion of maybe if that’s due to prior immunity or something, but it seems like things are still just not clear, and more data is coming down the pipe.

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